Local inflammation and hypoxia abolish the protective anticontractile properties of perivascular fat in obese patients AS Greenstein, K Khavandi, SB Withers, K Sonoyama, O Clancy, ... Circulation 119 (12), 1661-1670, 2009 | 724 | 2009 |
Diabetic cardiomyopathy O Asghar, A Al-Sunni, K Khavandi, A Khavandi, S Withers, A Greenstein, ... Clinical science 116 (10), 741-760, 2009 | 293 | 2009 |
Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue SN Saxton, BJ Clark, SB Withers, EC Eringa, AM Heagerty Physiological reviews 99 (4), 1701-1763, 2019 | 239 | 2019 |
Perivascular adipose tissue-derived adiponectin activates BKCa channels to induce anticontractile responses FM Lynch, SB Withers, Z Yao, ME Werner, G Edwards, AH Weston, ... American Journal of Physiology-Heart and Circulatory Physiology 304 (6 …, 2013 | 164 | 2013 |
Macrophage activation is responsible for loss of anticontractile function in inflamed perivascular fat SB Withers, C Agabiti-Rosei, DM Livingstone, MC Little, R Aslam, ... Arteriosclerosis, thrombosis, and vascular biology 31 (4), 908-913, 2011 | 124 | 2011 |
Perivascular adipose tissue from human systemic and coronary vessels: the emergence of a new pharmacotherapeutic target R Aghamohammadzadeh, S Withers, F Lynch, A Greenstein, R Malik, ... British journal of pharmacology 165 (3), 670-682, 2012 | 123 | 2012 |
Diabetic cardiomyopathy–a distinct disease? K Khavandi, A Khavandi, O Asghar, A Greenstein, S Withers, ... Best practice & research Clinical endocrinology & metabolism 23 (3), 347-360, 2009 | 118 | 2009 |
Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat CE Bussey, SB Withers, RG Aldous, G Edwards, AM Heagerty Arteriosclerosis, thrombosis, and vascular biology 36 (7), 1377-1385, 2016 | 108 | 2016 |
Eosinophils are key regulators of perivascular adipose tissue and vascular functionality SB Withers, R Forman, S Meza-Perez, D Sorobetea, K Sitnik, T Hopwood, ... Scientific Reports 7 (1), 44571, 2017 | 96 | 2017 |
Mechanisms of adiponectin-associated perivascular function in vascular disease SB Withers, CE Bussey, SN Saxton, HM Melrose, AE Watkins, ... Arteriosclerosis, thrombosis, and vascular biology 34 (8), 1637-1642, 2014 | 81 | 2014 |
Role of sympathetic nerves and adipocyte catecholamine uptake in the vasorelaxant function of perivascular adipose tissue SN Saxton, KE Ryding, RG Aldous, SB Withers, J Ohanian, AM Heagerty Arteriosclerosis, thrombosis, and vascular biology 38 (4), 880-891, 2018 | 73 | 2018 |
Myogenic tone and small artery remodelling: insight into diabetic nephropathy K Khavandi, AS Greenstein, K Sonoyama, S Withers, A Price, RA Malik, ... Nephrology Dialysis Transplantation 24 (2), 361-369, 2009 | 63 | 2009 |
Anticontractile activity of perivascular fat in obese mice and the effect of long-term treatment with melatonin C Agabiti-Rosei, C De Ciuceis, C Rossini, E Porteri, LF Rodella, ... Journal of hypertension 32 (6), 1264-1274, 2014 | 61 | 2014 |
cGMP-dependent protein kinase (PKG) mediates the anticontractile capacity of perivascular adipose tissue SB Withers, L Simpson, S Fattah, ME Werner, AM Heagerty Cardiovascular research 101 (1), 130-137, 2014 | 61 | 2014 |
Modulation of vascular reactivity by perivascular adipose tissue (PVAT) C Agabiti-Rosei, A Paini, C De Ciuceis, S Withers, A Greenstein, ... Current hypertension reports 20, 1-11, 2018 | 57 | 2018 |
Emerging roles of sympathetic nerves and inflammation in perivascular adipose tissue SN Saxton, SB Withers, AM Heagerty Cardiovascular drugs and therapy 33, 245-259, 2019 | 43 | 2019 |
β3‐Adrenoceptor stimulation of perivascular adipocytes leads to increased fat cell‐derived NO and vascular relaxation in small arteries CE Bussey, SB Withers, SN Saxton, N Bodagh, RG Aldous, AM Heagerty British journal of pharmacology 175 (18), 3685-3698, 2018 | 37 | 2018 |
Blockade of the renin–angiotensin system in small arteries and anticontractile function of perivascular adipose tissue CA Rosei, SB Withers, L Belcaid, C De Ciuceis, D Rizzoni, AM Heagerty Journal of hypertension 33 (5), 1039-1045, 2015 | 35 | 2015 |
Controlled delivery of antisense oligodeoxynucleotide from cationically modified phosphorylcholine polymer films ZQ Zhang, XC Cao, XB Zhao, SB Withers, CM Holt, AL Lewis, JR Lu Biomacromolecules 7 (3), 784-791, 2006 | 35 | 2006 |
Restoring perivascular adipose tissue function in obesity using exercise SN Saxton, LK Toms, RG Aldous, SB Withers, J Ohanian, AM Heagerty Cardiovascular drugs and therapy, 1-14, 2021 | 33 | 2021 |