Fast and Flexible Protein Design Using Deep Graph Neural Networks A Strokach, D Becerra, C Corbi-Verge, A Perez-Riba, PM Kim Cell Systems 11 (4), 402-411. e4, 2020 | 259 | 2020 |
The tetratricopeptide-repeat motif is a versatile platform that enables diverse modes of molecular recognition A Perez-Riba, LS Itzhaki Current opinion in structural biology 54, 43-49, 2019 | 132 | 2019 |
Computational Design of Potent D-Peptide Inhibitors of SARS-CoV-2 PA Valiente, H Wen, S Nim, JA Lee, HJ Kim, J Kim, A Perez-Riba, ... Journal of Medicinal Chemistry 64 (20), 14955-14967, 2021 | 52 | 2021 |
Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease S Nim, DM O’Hara, C Corbi-Verge, A Perez-Riba, K Fujisawa, M Kapadia, ... Nature Communications 14 (1), 2150, 2023 | 35 | 2023 |
A method for rapid high-throughput biophysical analysis of proteins A Perez-Riba, LS Itzhaki Scientific reports 7 (1), 1-6, 2017 | 31 | 2017 |
Folding cooperativity and allosteric function in the tandem-repeat protein class A Perez-Riba, M Synakewicz, LS Itzhaki Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 25 | 2018 |
Fast and flexible design of novel proteins using graph neural networks A Strokach, D Becerra, C Corbi-Verge, A Perez-Riba, PM Kim BioRxiv, 868935, 2019 | 21 | 2019 |
Dissecting and reprogramming the folding and assembly of tandem-repeat proteins PJE Rowling, EM Sivertsson, A Perez-Riba, ERG Main, LS Itzhaki Biochemical Society Transactions 43 (5), 881-888, 2015 | 20 | 2015 |
Exploring new strategies for grafting binding peptides onto protein loops using a consensus‐designed tetratricopeptide repeat scaffold SK Madden, A Perez‐Riba, LS Itzhaki Protein Science 28 (4), 738-745, 2019 | 18 | 2019 |
Engineering mono-and multi-valent inhibitors on a modular scaffold A Diamante, PK Chaturbedy, PJE Rowling, JR Kumita, RS Eapen, ... Chemical science 12 (3), 880-895, 2021 | 14 | 2021 |
Context-dependent energetics of loop extensions in a family of tandem-repeat proteins A Perez-Riba, AR Lowe, ERG Main, LS Itzhaki Biophysical journal 114 (11), 2552-2562, 2018 | 14 | 2018 |
Testing the length limit of loop grafting in a helical repeat protein JF Ripka, A Perez-Riba, PK Chaturbedy, LS Itzhaki Current Research in Structural Biology 3, 30-40, 2021 | 11 | 2021 |
PyFolding: open-source graphing, simulation, and analysis of the biophysical properties of proteins AR Lowe, A Perez-Riba, LS Itzhaki, ERG Main Biophysical journal 114 (3), 516-521, 2018 | 11 | 2018 |
Unraveling the mechanics of a repeat-protein nanospring: From folding of individual repeats to fluctuations of the superhelix M Synakewicz, RS Eapen, A Perez-Riba, PJE Rowling, D Bauer, A Weißl, ... ACS nano 16 (3), 3895-3905, 2022 | 10 | 2022 |
Decoupling a tandem-repeat protein: Impact of multiple loop insertions on a modular scaffold A Perez-Riba, E Komives, ERG Main, LS Itzhaki Scientific Reports 9 (1), 15439, 2019 | 8 | 2019 |
Computational generation of proteins with predetermined three-dimensional shapes using ProteinSolver A Strokach, D Becerra, C Corbi-Verge, A Perez-Riba, PM Kim STAR Protocols 2 (2), 100505, 2021 | 5 | 2021 |
Consensus tetratricopeptide repeat proteins are complex superhelical nanosprings M Synakewicz, RS Eapen, A Perez-Riba, D Bauer, A Weißl, G Fischer, ... bioRxiv, 2021.03. 27.437344, 2021 | 2 | 2021 |
The Effect of Loop Insertions on the Folding of Tandem-Repeat Proteins A Perez-Riba, ER Main, LS Itzhaki Biophysical Journal 110 (3), 181a, 2016 | | 2016 |