| Advances and challenges in small‐molecule DNA aptamer isolation, characterization, and sensor development H Yu, O Alkhamis, J Canoura, Y Liu, Y Xiao Angewandte Chemie International Edition 60 (31), 16800-16823, 2021 | 332 | 2021 |
| Innovative engineering and sensing strategies for aptamer-based small-molecule detection O Alkhamis, J Canoura, H Yu, Y Liu, Y Xiao TrAC Trends in Analytical Chemistry 121, 115699, 2019 | 136 | 2019 |
| Immobilization strategies for enhancing sensitivity of electrochemical aptamer-based sensors Y Liu, J Canoura, O Alkhamis, Y Xiao ACS applied materials & interfaces 13 (8), 9491-9499, 2021 | 91 | 2021 |
| No structure-switching required: a generalizable exonuclease-mediated aptamer-based assay for small-molecule detection J Canoura, Z Wang, H Yu, O Alkhamis, F Fu, Y Xiao Journal of the American Chemical Society 140 (31), 9961-9971, 2018 | 80 | 2018 |
| Accelerating post-SELEX aptamer engineering using exonuclease digestion J Canoura, H Yu, O Alkhamis, D Roncancio, R Farhana, Y Xiao Journal of the American Chemical Society 143 (2), 805-816, 2020 | 75 | 2020 |
| Label-free, visual detection of small molecules using highly target-responsive multimodule split aptamer constructs Y Luo, H Yu, O Alkhamis, Y Liu, X Lou, B Yu, Y Xiao Analytical chemistry 91 (11), 7199-7207, 2019 | 72 | 2019 |
| Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation Z Wang, H Yu, J Canoura, Y Liu, O Alkhamis, F Fu, Y Xiao Nucleic acids research 46 (13), e81-e81, 2018 | 72 | 2018 |
| In vitro isolation of class-specific oligonucleotide-based small-molecule receptors W Yang, H Yu, O Alkhamis, Y Liu, J Canoura, F Fu, Y Xiao Nucleic acids research 47 (12), e71-e71, 2019 | 63 | 2019 |
| Fabrication of Aptamer‐modified paper electrochemical devices for on‐site biosensing H Yu, Z Chen, Y Liu, O Alkhamis, Z Song, Y Xiao Angewandte Chemie 133 (6), 3030-3037, 2021 | 62 | 2021 |
| Isolation of natural DNA aptamers for challenging small-molecule targets, cannabinoids H Yu, Y Luo, O Alkhamis, J Canoura, B Yu, Y Xiao Analytical chemistry 93 (6), 3172-3180, 2021 | 56 | 2021 |
| In vitro isolation of small-molecule-binding aptamers with intrinsic dye-displacement functionality H Yu, W Yang, O Alkhamis, J Canoura, KA Yang, Y Xiao Nucleic Acids Research 46 (8), e43-e43, 2018 | 49 | 2018 |
| Tuning biosensor cross-reactivity using aptamer mixtures Y Liu, H Yu, O Alkhamis, J Moliver, Y Xiao Analytical chemistry 92 (7), 5041-5047, 2020 | 42 | 2020 |
| Sensitive detection of small-molecule targets using cooperative binding split aptamers and enzyme-assisted target recycling H Yu, J Canoura, B Guntupalli, O Alkhamis, Y Xiao Analytical chemistry 90 (3), 1748-1758, 2018 | 42 | 2018 |
| DNA Aptamer–Cyanine Complexes as Generic Colorimetric Small‐Molecule Sensors O Alkhamis, J Canoura, KV Bukhryakov, A Tarifa, AP DeCaprio, Y Xiao Angewandte Chemie 134 (3), e202112305, 2022 | 36 | 2022 |
| Label-free profiling of DNA aptamer-small molecule binding using T5 exonuclease O Alkhamis, W Yang, R Farhana, H Yu, Y Xiao Nucleic Acids Research 48 (20), e120-e120, 2020 | 32 | 2020 |
| Dithiothreitol-regulated coverage of oligonucleotide-modified gold nanoparticles to achieve optimized biosensor performance P Liang, J Canoura, H Yu, O Alkhamis, Y Xiao ACS applied materials & interfaces 10 (4), 4233-4242, 2018 | 32 | 2018 |
| Systematic Study of in Vitro Selection Stringency Reveals How To Enrich High-Affinity Aptamers O Alkhamis, Y Xiao Journal of the American Chemical Society 145 (1), 194-206, 2022 | 29 | 2022 |
| Using exonucleases for aptamer characterization, engineering, and sensing O Alkhamis, J Canoura, PT Ly, Y Xiao Accounts of Chemical Research 56 (13), 1731-1743, 2023 | 23 | 2023 |
| High-Affinity Aptamers for In Vitro and In Vivo Cocaine Sensing O Alkhamis, J Canoura, Y Wu, NA Emmons, Y Wang, KM Honeywell, ... Journal of the American Chemical Society 146 (5), 3230-3240, 2024 | 19 | 2024 |
| Comparison of aptamer signaling mechanisms reveals disparities in sensor response and strategies to eliminate false signals O Alkhamis, J Canoura, C Willis, L Wang, J Perry, Y Xiao Journal of the American Chemical Society 145 (22), 12407-12422, 2023 | 19 | 2023 |
