Synthesis of novel 1, 2, 3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation D Kumar, G Khare, S Kidwai, AK Tyagi, R Singh, DS Rawat European journal of medicinal chemistry 81, 301-313, 2014 | 114 | 2014 |
Functional Studies of Multiple Thioredoxins from Mycobacterium tuberculosis M Akif, G Khare, AK Tyagi, SC Mande, AA Sardesai Journal of bacteriology 190 (21), 7087-7095, 2008 | 84 | 2008 |
Ferritin Structure from Mycobacterium tuberculosis: Comparative Study with Homologues Identifies Extended C-Terminus Involved in Ferroxidase Activity G Khare, V Gupta, P Nangpal, RK Gupta, NK Sauter, AK Tyagi PloS one 6 (4), e18570, 2011 | 71 | 2011 |
A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL D Basu, G Khare, S Singh, A Tyagi, S Khosla, SC Mande Nucleic acids research 37 (15), 4944-4954, 2009 | 70 | 2009 |
Differential Roles of Iron Storage Proteins in Maintaining the Iron Homeostasis in Mycobacterium tuberculosis G Khare, P Nangpal, AK Tyagi PLoS One 12 (1), e0169545, 2017 | 60 | 2017 |
Facilitated oligomerization of mycobacterial GroEL: evidence for phosphorylation-mediated oligomerization CMS Kumar, G Khare, CV Srikanth, AK Tyagi, AA Sardesai, SC Mande Journal of bacteriology 191 (21), 6525-6538, 2009 | 55 | 2009 |
Necrosis Driven Triglyceride Synthesis Primes Macrophages for Inflammation During Mycobacterium tuberculosis Infection N Jaisinghani, S Dawa, K Singh, A Nandy, D Menon, PD Bhandari, ... Frontiers in Immunology 9, 1490, 2018 | 53 | 2018 |
Crystal Structure of Bfr A from Mycobacterium tuberculosis: Incorporation of Selenomethionine Results in Cleavage and Demetallation of Haem V Gupta, RK Gupta, G Khare, DM Salunke, AK Tyagi PloS one 4 (11), e8028, 2009 | 47 | 2009 |
Virtual Screening, pharmacophore development and structure based similarity search to identify inhibitors against IdeR, a transcription factor of Mycobacterium tuberculosis A Rohilla, G Khare, AK Tyagi Scientific reports 7 (1), 4653, 2017 | 44 | 2017 |
Identification of Inhibitors against Mycobacterium tuberculosis Thiamin Phosphate Synthase, an Important Target for the Development of Anti-TB Drugs G Khare, R Kar, AK Tyagi PLoS One 6 (7), e22441, 2011 | 42 | 2011 |
Novel isoniazid–amidoether derivatives: synthesis, characterization and antimycobacterial activity evaluation D Kumar, G Khare, S Kidwai, AK Tyagi, R Singh, DS Rawat MedChemComm 6 (1), 131-137, 2015 | 38 | 2015 |
Dissecting the Role of Critical Residues and Substrate Preference of a Fatty Acyl-CoA Synthetase (FadD13) of Mycobacterium tuberculosis G Khare, V Gupta, RK Gupta, R Gupta, R Bhat, AK Tyagi PLoS One 4 (12), e8387, 2009 | 35 | 2009 |
Structural ordering of disordered ligand-binding loops of biotin protein ligase into active conformations as a consequence of dehydration V Gupta, RK Gupta, G Khare, DM Salunke, A Surolia, AK Tyagi PLoS One 5 (2), e9222, 2010 | 31 | 2010 |
Molecular modeling studies of Fatty acyl-CoA synthetase (FadD13) from Mycobacterium tuberculosis—a potential target for the development of antitubercular drugs N Jatana, S Jangid, G Khare, AK Tyagi, N Latha Journal of molecular modeling 17, 301-313, 2011 | 28 | 2011 |
Unraveling the role of the transcriptional regulator VirS in low pH–induced responses of Mycobacterium tuberculosis and identification of VirS inhibitors S Singh, N Goswami, AK Tyagi, G Khare Journal of Biological Chemistry 294 (26), 10055-10075, 2019 | 19 | 2019 |
Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening S Singh, G Khare, RK Bahal, PC Ghosh, AK Tyagi Drug design, development and therapy, 1065-1079, 2018 | 18 | 2018 |
Whole-cell screening-based identification of inhibitors against the intraphagosomal survival of Mycobacterium tuberculosis G Khare, P Kumar, AK Tyagi Antimicrobial agents and chemotherapy 57 (12), 6372-6377, 2013 | 15 | 2013 |
A combination of docking and cheminformatics approaches for the identification of inhibitors against 4′ phosphopantetheinyl transferase of Mycobacterium tuberculosis A Rohilla, G Khare, AK Tyagi RSC Advances 8 (1), 328-341, 2018 | 14 | 2018 |
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of bacterioferritin A from Mycobacterium tuberculosis V Gupta, RK Gupta, G Khare, DM Salunke, AK Tyagi Structural Biology and Crystallization Communications 64 (5), 398-401, 2008 | 14 | 2008 |
Antisense oligonucleotide based therapeutics and its applications against bacterial infections N Angrish, G Khare Medicine in Drug Discovery 20, 100166, 2023 | 13 | 2023 |