HIV latency in isolated patient CD4+ T cells may be due to blocks in HIV transcriptional elongation, completion, and splicing SA Yukl, P Kaiser, P Kim, S Telwatte, SK Joshi, M Vu, H Lampiris, ... Science Translational Medicine 10 (430), 2018 | 305 | 2018 |
Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1 S Telwatte, K Moore, A Johnson, D Tyssen, J Sterjovski, M Aldunate, ... Antiviral research 90 (3), 195-199, 2011 | 121 | 2011 |
Gut and blood differ in constitutive blocks to HIV transcription, suggesting tissue-specific differences in the mechanisms that govern HIV latency S Telwatte, S Lee, M Somsouk, H Hatano, C Baker, P Kaiser, P Kim, ... PLoS pathogens 14 (11), e1007357, 2018 | 111 | 2018 |
Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir J Neidleman, X Luo, J Frouard, G Xie, F Hsiao, T Ma, V Morcilla, A Lee, ... Elife 9, e60933, 2020 | 79 | 2020 |
The Atlas of the In Vivo HIV CD4 T Cell Reservoir J Neidleman, X Luo, J Frouard, G Xie, F Hsiao, T Ma, V Morcilla, A Lee, ... bioRxiv, 2020 | 79* | 2020 |
Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency S Telwatte, S Morón-López, D Aran, P Kim, C Hsieh, S Joshi, M Montano, ... Retrovirology 16 (1), 1-23, 2019 | 51 | 2019 |
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection F Hsiao, J Frouard, A Gramatica, G Xie, S Telwatte, GQ Lee, ... PLoS pathogens 16 (4), e1008450, 2020 | 39 | 2020 |
An optimized and validated method for isolation and characterization of lymphocytes from HIV+ human gut biopsies M Trapecar, S Khan, NR Roan, TH Chen, S Telwatte, M Deswal, M Pao, ... AIDS research and human retroviruses 33 (S1), S-31-S-39, 2017 | 37 | 2017 |
Novel RT-ddPCR assays for measuring the levels of subgenomic and genomic SARS-CoV-2 transcripts S Telwatte, HA Martin, R Marczak, P Fozouni, A Vallejo-Gracia, GR Kumar, ... Methods 201, 15-25, 2022 | 35 | 2022 |
Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals S Moron-Lopez, S Telwatte, I Sarabia, E Battivelli, M Montano, ... PLoS pathogens 16 (11), e1009060, 2020 | 31 | 2020 |
Differentiating immune cell targets in gut-associated lymphoid tissue for HIV cure S Khan, S Telwatte, M Trapecar, S Yukl, S Sanjabi AIDS research and human retroviruses 33 (S1), S-40-S-58, 2017 | 29 | 2017 |
Combination anti-HIV therapy via tandem release of prodrugs from macromolecular carriers M Danial, S Telwatte, D Tyssen, S Cosson, G Tachedjian, G Moad, ... Polymer Chemistry 7 (48), 7477-7487, 2016 | 27 | 2016 |
Antiretroviral Therapy Concentrations Differ in Gut vs. Lymph Node Tissues and Are Associated With HIV Viral Transcription by a Novel RT-ddPCR Assay SA Lee, S Telwatte, H Hatano, ADM Kashuba, ML Cottrell, R Hoh, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 83 (5), 530-537, 2020 | 26 | 2020 |
Novel RT-ddPCR assays for simultaneous quantification of multiple noncoding and coding regions of SARS-CoV-2 RNA S Telwatte, N Kumar, A Vallejo-Gracia, GR Kumar, CM Lu, M Ott, JK Wong, ... Journal of virological methods, 114115, 2021 | 21 | 2021 |
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import KM Wagstaff, S Headey, S Telwatte, D Tyssen, AC Hearps, DR Thomas, ... Cellular microbiology 21 (1), e12953, 2019 | 21 | 2019 |
Mechanistic differences underlying HIV latency in the gut and blood contribute to differential responses to latency-reversing agents S Telwatte, P Kim, TH Chen, JM Milush, M Somsouk, SG Deeks, PW Hunt, ... Aids 34 (14), 2013-2024, 2020 | 19 | 2020 |
New Assay Reveals Vast Excess of Defective over Intact HIV-1 Transcripts in Antiretroviral Therapy-Suppressed Individuals HA Martin, GN Kadiyala, S Telwatte, A Wedrychowski, TH Chen, ... Journal of Virology 96 (24), e01605-22, 2022 | 15 | 2022 |
Transcriptomic signatures of human immunodeficiency virus post-treatment control A Wedrychowski, HA Martin, Y Li, S Telwatte, GN Kadiyala, M Melberg, ... Journal of Virology 97 (1), e01254-22, 2023 | 13 | 2023 |
Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations S Telwatte, AC Hearps, A Johnson, CF Latham, K Moore, P Agius, ... Nucleic acids research 43 (6), 3256-3271, 2015 | 13 | 2015 |
Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103+ and Gut CD4+ T Cells SA Yukl, S Khan, TH Chen, M Trapecar, F Wu, G Xie, S Telwatte, D Fulop, ... Journal of Virology 95 (2), 2020 | 6 | 2020 |