| Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis JY Guo, HY Chen, R Mathew, J Fan, AM Strohecker, G Karsli-Uzunbas, ... Genes & development 25 (5), 460-470, 2011 | 1508 | 2011 |
| Quantitative flux analysis reveals folate-dependent NADPH production J Fan, J Ye, JJ Kamphorst, T Shlomi, CB Thompson, JD Rabinowitz Nature 510 (7504), 298-302, 2014 | 1135 | 2014 |
| Gut microbial metabolites as multi-kingdom intermediates KA Krautkramer, J Fan, F Bäckhed Nature Reviews Microbiology 19 (2), 77-94, 2021 | 929 | 2021 |
| Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids JJ Kamphorst, JR Cross, J Fan, E De Stanchina, R Mathew, EP White, ... Proceedings of the National Academy of Sciences 110 (22), 8882-8887, 2013 | 756 | 2013 |
| Glutamine‐driven oxidative phosphorylation is a major ATP source in transformed mammalian cells in both normoxia and hypoxia J Fan, JJ Kamphorst, R Mathew, MK Chung, E White, T Shlomi, ... Molecular systems biology 9 (1), 712, 2013 | 490 | 2013 |
| Serine catabolism regulates mitochondrial redox control during hypoxia J Ye, J Fan, S Venneti, YW Wan, BR Pawel, J Zhang, LWS Finley, C Lu, ... Cancer discovery 4 (12), 1406-1417, 2014 | 459 | 2014 |
| Metabolite concentrations, fluxes and free energies imply efficient enzyme usage JO Park, SA Rubin, YF Xu, D Amador-Noguez, J Fan, T Shlomi, ... Nature chemical biology 12 (7), 482-489, 2016 | 439 | 2016 |
| Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion J Zhang, J Fan, S Venneti, JR Cross, T Takagi, B Bhinder, H Djaballah, ... Molecular cell 56 (2), 205-218, 2014 | 434 | 2014 |
| Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation J Ye, A Mancuso, X Tong, PS Ward, J Fan, JD Rabinowitz, CB Thompson Proceedings of the National Academy of Sciences 109 (18), 6904-6909, 2012 | 428 | 2012 |
| Metabolic regulation of histone post-translational modifications J Fan, KA Krautkramer, JL Feldman, JM Denu ACS chemical biology 10 (1), 95-108, 2015 | 352 | 2015 |
| As extracellular glutamine levels decline, asparagine becomes an essential amino acid NN Pavlova, S Hui, JM Ghergurovich, J Fan, AM Intlekofer, RM White, ... Cell metabolism 27 (2), 428-438. e5, 2018 | 330 | 2018 |
| Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate JJ Kamphorst, MK Chung, J Fan, JD Rabinowitz Cancer & metabolism 2, 1-8, 2014 | 256 | 2014 |
| Human Phosphoglycerate Dehydrogenase Produces the Oncometabolite d-2-Hydroxyglutarate J Fan, X Teng, L Liu, KR Mattaini, RE Looper, MG Vander Heiden, ... ACS chemical biology 10 (2), 510-516, 2015 | 204 | 2015 |
| SIRT3 mediates multi-tissue coupling for metabolic fuel switching KE Dittenhafer-Reed, AL Richards, J Fan, MJ Smallegan, AF Siahpirani, ... Cell metabolism 21 (4), 637-646, 2015 | 194 | 2015 |
| Autophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibition K Bray, R Mathew, A Lau, JJ Kamphorst, J Fan, J Chen, HY Chen, ... PloS one 7 (7), e41831, 2012 | 178 | 2012 |
| Stoichiometry of Site-specific Lysine Acetylation in an Entire Proteome*♦ J Baeza, JA Dowell, MJ Smallegan, J Fan, D Amador-Noguez, Z Khan, ... Journal of Biological Chemistry 289 (31), 21326-21338, 2014 | 175 | 2014 |
| The pentose phosphate pathway in health and disease T TeSlaa, M Ralser, J Fan, JD Rabinowitz Nature metabolism 5 (8), 1275-1289, 2023 | 166 | 2023 |
| Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in Clostridium acetobutylicum D Amador-Noguez, XJ Feng, J Fan, N Roquet, H Rabitz, JD Rabinowitz Journal of bacteriology 192 (17), 4452-4461, 2010 | 160 | 2010 |
| A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway JM Ghergurovich, JC García-Cañaveras, J Wang, E Schmidt, Z Zhang, ... Nature chemical biology 16 (7), 731-739, 2020 | 149 | 2020 |
| Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage L Liu, S Shah, J Fan, JO Park, KE Wellen, JD Rabinowitz Nature chemical biology 12 (5), 345-352, 2016 | 143 | 2016 |
