| Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase C Wang, W Li, J Ren, J Fang, H Ke, W Gong, W Feng, C Wang Antioxidants & redox signaling 19 (1), 36-45, 2013 | 245 | 2013 |
| Human protein-disulfide isomerase is a redox-regulated chaperone activated by oxidation of domain a′ C Wang, J Yu, L Huo, L Wang, W Feng, C Wang Journal of Biological Chemistry 287 (2), 1139-1149, 2012 | 156 | 2012 |
| Plasticity of human protein disulfide isomerase: evidence for mobility around the X-linker region and its functional significance C Wang, S Chen, X Wang, L Wang, AK Wallis, RB Freedman, C Wang Journal of Biological Chemistry 285 (35), 26788-26797, 2010 | 78 | 2010 |
| Compact conformations of human protein disulfide isomerase S Yang, X Wang, L Cui, X Ding, L Niu, F Yang, C Wang, C Wang, J Lou PLoS One 9 (8), e103472, 2014 | 44 | 2014 |
| Bridging Genomics to Phenomics at Atomic Resolution through Variation Spatial Profiling C Wang, WE Balch Cell reports 24 (8), 2013-2028. e6, 2018 | 39 | 2018 |
| Quantitating the epigenetic transformation contributing to cholesterol homeostasis using Gaussian process C Wang, SM Scott, K Subramanian, S Loguercio, P Zhao, H Darren M., ... Nature Communications 10, 5052, 2019 | 28 | 2019 |
| Individualized Management of Genetic Diversity in Niemann-Pick C1 through Modulation of the Hsp70 Chaperone System C Wang, SM Scott, S Sun, P Zhao, DM Hutt, H Shao, JE Gestwicki, ... Human Molecular Genetics, 2020 | 23 | 2020 |
| Spatial covariance analysis reveals the residue-by-residue thermodynamic contribution of variation to the CFTR fold F Anglès, C Wang, WE Balch Communications Biology 5 (1), 356, 2022 | 15 | 2022 |
| Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis S Sun, C Wang, P Zhao, GM Kline, JMD Grandjean, X Jiang, ... Cell chemical biology 30 (1), 22-42. e5, 2023 | 11 | 2023 |
| Leveraging Population Genomics for Individualized Correction of the Hallmarks of Alpha-1 Antitrypsin Deficiency C Wang, P Zhao, S Sun, J Teckman, WE Balch Chronic Obstr Pulm Dis. 7 (3), 224-246, 2020 | 9 | 2020 |
| Triangulating variation in the population to define mechanisms for precision management of genetic disease C Wang, F Anglès, WE Balch Structure 30 (8), 1190-1207. e5, 2022 | 8 | 2022 |
| Measuring the effect of histone deacetylase inhibitors (HDACi) on the secretion and activity of alpha-1 antitrypsin C Wang, M Bouchecareilh, WE Balch Methods in Molecular Biology (Alpha-1 Antitrypsin Deficiency), 185-193, 2017 | 7 | 2017 |
| Covariant fitness clusters reveal structural evolution of SARS-CoV-2 polymerase across the human population C Wang, N Elghobashi-Meinhardt, WE Balch bioRxiv, 2022.01. 07.475295, 2022 | 6 | 2022 |
| Structural basis for the transport and substrate selection of human urate transporter 1 J He, G Liu, F Kong, Q Tan, Z Wang, M Yang, Y He, X Jia, C Yan, C Wang, ... Cell Reports 43 (8), 2024 | 5 | 2024 |
| Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiency C Wang, WE Balch Respiratory Medicine (Alpha-1 Antitrypsin Role in Health and Disease), 53-83, 2016 | 5 | 2016 |
| Profiling Genetic Diversity Reveals the Molecular Basis for Balancing Function with Misfolding in Alpha-1 Antitrypsin C Wang, Z Pei, S Sun, X Wang, WE Balch bioRxiv, 2022 | 4 | 2022 |
| Tracing genetic diversity captures the molecular basis of misfolding disease P Zhao, C Wang, S Sun, X Wang, WE Balch Nature Communications 15 (1), 3333, 2024 | 3 | 2024 |
| Understanding the host-pathogen evolutionary balance through Gaussian process modeling of SARS-CoV-2 S Loguercio, BC Calverley, C Wang, D Shak, P Zhao, S Sun, ... Patterns 4 (8), 2023 | 2 | 2023 |
| COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation F Anglès, V Gupta, C Wang, WE Balch Scientific Reports 14 (1), 10160, 2024 | | 2024 |
| Spatial covariance analysis reveals the residue-by-residue thermodynamic contribution of variation to the CFTR fold A Frédéric, C Wang, WE Balch Communications Biology 5 (1), 2022 | | 2022 |
