Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth JB Baell, DJ Leaver, SJ Hermans, GL Kelly, MS Brennan, NL Downer, ... Nature 560 (7717), 253-257, 2018 | 249 | 2018 |
The many lives of KATs—detectors, integrators and modulators of the cellular environment BN Sheikh, A Akhtar Nature Reviews Genetics 20 (1), 7-23, 2019 | 154 | 2019 |
Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome–like phenotype and hyperactivated MAPK signaling in humans and mice M Kraft, IC Cirstea, AK Voss, T Thomas, I Goehring, BN Sheikh, L Gordon, ... The Journal of clinical investigation 121 (9), 2011 | 137 | 2011 |
MOZ regulates the Tbx1 locus, and Moz mutation partially phenocopies DiGeorge syndrome AK Voss, HK Vanyai, C Collin, MP Dixon, TJ McLennan, BN Sheikh, ... Developmental cell 23 (3), 652-663, 2012 | 105 | 2012 |
C3G regulates cortical neuron migration, preplate splitting and radial glial cell attachment AK Voss, JM Britto, MP Dixon, BN Sheikh, C Collin, SS Tan, T Thomas Oxford University Press for The Company of Biologists Limited 135 (12), 2139 …, 2008 | 105 | 2008 |
MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells BN Sheikh, Y Yang, J Schreuder, SK Nilsson, R Bilardi, S Carotta, ... Blood, The Journal of the American Society of Hematology 128 (19), 2307-2318, 2016 | 99 | 2016 |
The non‐specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis BN Sheikh, S Guhathakurta, A Akhtar EMBO reports 20 (7), e47630, 2019 | 94 | 2019 |
MOZ (MYST3, KAT6A) inhibits senescence via the INK4A-ARF pathway BN Sheikh, B Phipson, F El-Saafin, HK Vanyai, NL Downer, MJ Bird, ... Oncogene 34 (47), 5807-5820, 2015 | 88 | 2015 |
MOF maintains transcriptional programs regulating cellular stress response BN Sheikh, W Bechtel-Walz, J Lucci, O Karpiuk, I Hild, B Hartleben, ... Oncogene 35 (21), 2698-2710, 2016 | 69 | 2016 |
MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development BN Sheikh, SCW Lee, F El-Saafin, HK Vanyai, Y Hu, SHM Pang, ... Blood, The Journal of the American Society of Hematology 125 (12), 1910-1921, 2015 | 63 | 2015 |
Crafting the brain–role of histone acetyltransferases in neural development and disease BN Sheikh Cell and Tissue Research 356 (3), 553-573, 2014 | 61 | 2014 |
Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity O Bondareva, JR Rodríguez-Aguilera, F Oliveira, L Liao, A Rose, A Gupta, ... Nature Metabolism 4 (11), 1591-1610, 2022 | 51 | 2022 |
Querkopf is a key marker of self-renewal and multipotency of adult neural stem cells BN Sheikh, MP Dixon, T Thomas, AK Voss Journal of cell science 125 (2), 295-309, 2012 | 51 | 2012 |
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity I AlZaim, LPMH de Rooij, BN Sheikh, E Börgeson, J Kalucka Nature Reviews Endocrinology 19 (12), 691-707, 2023 | 45 | 2023 |
PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia HM McRae, AL Garnham, Y Hu, MT Witkowski, MA Corbett, MP Dixon, ... Blood, The Journal of the American Society of Hematology 133 (16), 1729-1741, 2019 | 45 | 2019 |
Systematic identification of cell-cell communication networks in the developing brain BN Sheikh, O Bondareva, S Guhathakurta, TH Tsang, K Sikora, ... IScience 21, 273-287, 2019 | 41 | 2019 |
Subtle changes in the levels of BCL-2 proteins cause severe craniofacial abnormalities S Grabow, AJ Kueh, F Ke, HK Vanyai, BN Sheikh, MA Dengler, W Chiang, ... Cell Reports 24 (12), 3285-3295. e4, 2018 | 41 | 2018 |
Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature BN Sheikh, S Guhathakurta, TH Tsang, M Schwabenland, G Renschler, ... Nature cell biology 22 (7), 828-841, 2020 | 36 | 2020 |
MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo BN Sheikh, NL Downer, B Phipson, HK Vanyai, AJ Kueh, DJ McCarthy, ... Proceedings of the National Academy of Sciences 112 (17), 5437-5442, 2015 | 35 | 2015 |
Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs KE Kokot, JM Kneuer, D John, S Rebs, MN Möbius-Winkler, S Erbe, ... Basic Research in Cardiology 117 (1), 32, 2022 | 30 | 2022 |