| Structures of α-synuclein filaments from human brains with Lewy pathology Y Yang, Y Shi, M Schweighauser, X Zhang, A Kotecha, AG Murzin, ... Nature 610 (7933), 791-795, 2022 | 275 | 2022 |
| Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand X Zhang, F Zhao, Y Wu, J Yang, GW Han, S Zhao, A Ishchenko, L Ye, ... Nature communications 8 (1), 15383, 2017 | 121 | 2017 |
| The importance of ligands for G protein-coupled receptor stability X Zhang, RC Stevens, F Xu Trends in biochemical sciences 40 (2), 79-87, 2015 | 93 | 2015 |
| Structural and druggability landscape of frizzled G protein-coupled receptors X Zhang, S Dong, F Xu Trends in Biochemical Sciences 43 (12), 1033-1046, 2018 | 53 | 2018 |
| New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy Y Yang, HJ Garringer, Y Shi, S Lövestam, S Peak-Chew, X Zhang, ... Acta Neuropathologica 145 (5), 561-572, 2023 | 43 | 2023 |
| Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography KL White, J Singla, V Loconte, JH Chen, A Ekman, L Sun, X Zhang, ... Science advances 6 (50), eabc8262, 2020 | 40 | 2020 |
| Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs L Xu, B Chen, H Schihada, SC Wright, A Turku, Y Wu, GW Han, ... Cell Research 31 (12), 1311-1314, 2021 | 37 | 2021 |
| Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography X Zhang, SD Carter, J Singla, KL White, PC Butler, RC Stevens, ... Science Advances 6 (50), eabc8258, 2020 | 28 | 2020 |
| The structure-based traceless specific fluorescence labeling of the smoothened receptor D Xue, L Ye, J Zheng, Y Wu, X Zhang, Y Xu, T Li, RC Stevens, F Xu, ... Organic & Biomolecular Chemistry 17 (25), 6136-6142, 2019 | 13 | 2019 |
| A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor L Ye, K Ding, F Zhao, X Liu, Y Wu, Y Liu, D Xue, F Zhou, X Zhang, ... MedChemComm 8 (6), 1332-1336, 2017 | 12 | 2017 |
| Colocalization strategy unveils an underside binding site in the transmembrane domain of smoothened receptor F Zhou, K Ding, Y Zhou, Y Liu, X Liu, F Zhao, Y Wu, X Zhang, Q Tan, F Xu, ... Journal of Medicinal Chemistry 62 (21), 9983-9989, 2019 | 6 | 2019 |
