| Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis SC Manolagas Endocrine reviews 21 (2), 115-137, 2000 | 3768 | 2000 |
| Bone marrow, cytokines, and bone remodeling—emerging insights into the pathophysiology of osteoporosis SC Manolagas, RL Jilka New England journal of medicine 332 (5), 305-311, 1995 | 2476 | 1995 |
| Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone. RS Weinstein, RL Jilka, AM Parfitt, SC Manolagas The Journal of clinical investigation 102 (2), 274-282, 1998 | 2223 | 1998 |
| Increased osteoclast development after estrogen loss: mediation by interleukin-6 RL Jilka, G Hangoc, G Girasole, G Passeri, DC Williams, JS Abrams, ... Science 257 (5066), 88-91, 1992 | 1880 | 1992 |
| The pathophysiologic roles of interleukin-6 in human disease DA Papanicolaou, RL Wilder, SC Manolagas, GP Chrousos Annals of internal medicine 128 (2), 127-137, 1998 | 1671 | 1998 |
| Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity S Kousteni, T Bellido, LI Plotkin, CA O'brien, DL Bodenner, L Han, K Han, ... Cell 104 (5), 719-730, 2001 | 1581 | 2001 |
| Matrix-embedded cells control osteoclast formation J Xiong, M Onal, RL Jilka, RS Weinstein, SC Manolagas, CA O'brien Nature medicine 17 (10), 1235-1241, 2011 | 1480 | 2011 |
| 1, 25-dihydroxyvitamin D3 receptors in human leukocytes DM Provvedini, CD Tsoukas, LJ Deftos, SC Manolagas Science 221 (4616), 1181-1183, 1983 | 1466 | 1983 |
| From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis SC Manolagas Endocrine reviews 31 (3), 266-300, 2010 | 1322 | 2010 |
| Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone RL Jilka, RS Weinstein, T Bellido, P Roberson, AM Parfitt, SC Manolagas The Journal of clinical investigation 104 (4), 439-446, 1999 | 1287 | 1999 |
| Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin LI Plotkin, RS Weinstein, AM Parfitt, PK Roberson, SC Manolagas, ... The Journal of clinical investigation 104 (10), 1363-1374, 1999 | 1155 | 1999 |
| Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength CA O’brien, D Jia, LI Plotkin, T Bellido, CC Powers, SA Stewart, ... Endocrinology 145 (4), 1835-1841, 2004 | 956 | 2004 |
| 17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of … G Girasole, RL Jilka, G Passeri, S Boswell, G Boder, DC Williams, ... The Journal of clinical investigation 89 (3), 883-891, 1992 | 874 | 1992 |
| Osteoblast programmed cell death (apoptosis): modulation by growth factors and cytokines RL Jilka, RS Weinstein, T Bellido, AM Parfitt, SC Manolagas Journal of bone and mineral research 13 (5), 793-802, 1998 | 851 | 1998 |
| Estrogens and androgens in skeletal physiology and pathophysiology M Almeida, MR Laurent, V Dubois, F Claessens, CA O'Brien, R Bouillon, ... Physiological reviews 97 (1), 135-187, 2017 | 838 | 2017 |
| Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids M Almeida, LI Han, M Martin-Millan, LI Plotkin, SA Stewart, PK Roberson, ... Journal of Biological Chemistry 282 (37), 27285-27297, 2007 | 796 | 2007 |
| 1, 25-dihydroxyvitamin D3: a novel immunoregulatory hormone CD Tsoukas, DM Provvedini, SC Manolagas Science 224 (4656), 1438-1440, 1984 | 752 | 1984 |
| Sex steroids and bone SC Manolagas, S Kousteni, RL Jilka Recent progress in hormone research 57, 385-410, 2002 | 741 | 2002 |
| Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis T Bellido, AA Ali, I Gubrij, LI Plotkin, Q Fu, CA O’brien, SC Manolagas, ... Endocrinology 146 (11), 4577-4583, 2005 | 725 | 2005 |
| The role of estrogen and androgen receptors in bone health and disease SC Manolagas, CA O'brien, M Almeida Nature Reviews Endocrinology 9 (12), 699, 2013 | 687 | 2013 |