| A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms JD Moreno, ZI Zhu, PC Yang, JR Bankston, MT Jeng, C Kang, L Wang, ... Science translational medicine 3 (98), 98ra83-98ra83, 2011 | 241 | 2011 |
| Ranolazine for Congenital and Acquired Late INa-Linked Arrhythmias: In Silico Pharmacological Screening JD Moreno, PC Yang, JR Bankston, E Grandi, DM Bers, RS Kass, ... Circulation research 113 (7), e50-e61, 2013 | 98 | 2013 |
| Computational approaches to understand cardiac electrophysiology and arrhythmias BN Roberts, PC Yang, SB Behrens, JD Moreno, CE Clancy American Journal of Physiology-Heart and Circulatory Physiology 303 (7 …, 2012 | 91 | 2012 |
| NFAT and NFκB activation in T lymphocytes: a model of differential activation of gene expression WG Fisher, PC Yang, RK Medikonduri, MS Jafri Annals of biomedical engineering 34, 1712-1728, 2006 | 86 | 2006 |
| Role of membrane microdomains in compartmentation of cAMP signaling SR Agarwal, PC Yang, M Rice, CA Singer, VO Nikolaev, MJ Lohse, ... PloS one 9 (4), e95835, 2014 | 85 | 2014 |
| Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study PC Yang, J Kurokawa, T Furukawa, CE Clancy PLoS computational biology 6 (1), e1000658, 2010 | 79 | 2010 |
| A computational pipeline to predict cardiotoxicity: from the atom to the rhythm PC Yang, KR DeMarco, P Aghasafari, MT Jeng, JRD Dawson, S Bekker, ... Circulation research 126 (8), 947-964, 2020 | 78 | 2020 |
| A novel heterozygous mutation in cardiac calsequestrin causes autosomal dominant catecholaminergic polymorphic ventricular tachycardia B Gray, RD Bagnall, L Lam, J Ingles, C Turner, E Haan, A Davis, PC Yang, ... Heart Rhythm 13 (8), 1652-1660, 2016 | 76 | 2016 |
| In silico Prediction of Sex-Based Differences in Human Susceptibility to Cardiac Ventricular Tachyarrhythmias PC Yang, CE Clancy Frontiers in physiology 3, 360, 2012 | 74 | 2012 |
| In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome L Romero, B Trenor, PC Yang, J Saiz, CE Clancy Journal of molecular and cellular cardiology 72, 126-137, 2014 | 69 | 2014 |
| Effects of sex hormones on cardiac repolarization PC Yang, CE Clancy Journal of cardiovascular pharmacology 56 (2), 123-129, 2010 | 60 | 2010 |
| A computational modeling and simulation approach to investigate mechanisms of subcellular cAMP compartmentation PC Yang, BW Boras, MT Jeng, SS Docken, TJ Lewis, AD McCulloch, ... PLoS Computational Biology 12 (7), e1005005, 2016 | 57 | 2016 |
| When Does the IC50 Accurately Assess the Blocking Potency of a Drug? J Gomis-Tena, BM Brown, J Cano, B Trenor, PC Yang, J Saiz, CE Clancy, ... Journal of chemical information and modeling 60 (3), 1779-1790, 2020 | 52 | 2020 |
| A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal‐induced arrhythmias PC Yang, LL Perissinotti, F López‐Redondo, Y Wang, KR DeMarco, ... The Journal of physiology 595 (14), 4695-4723, 2017 | 47 | 2017 |
| Compartmentalized cAMP signaling associated with lipid raft and non-raft membrane domains in adult ventricular myocytes SR Agarwal, J Gratwohl, M Cozad, PC Yang, CE Clancy, RD Harvey Frontiers in pharmacology 9, 332, 2018 | 45 | 2018 |
| In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia PC Yang, JD Moreno, CY Miyake, SB Vaughn‐Behrens, MT Jeng, ... The Journal of physiology 594 (3), 567-593, 2016 | 42 | 2016 |
| Sex‐specific classification of drug‐induced torsade de pointes susceptibility using cardiac simulations and machine learning A Fogli Iseppe, H Ni, S Zhu, X Zhang, R Coppini, PC Yang, U Srivatsa, ... Clinical Pharmacology & Therapeutics 110 (2), 380-391, 2021 | 39 | 2021 |
| Determinants of isoform-specific gating kinetics of hERG1 channel: combined experimental and simulation study LL Perissinotti, PM De Biase, J Guo, PC Yang, MC Lee, CE Clancy, ... Frontiers in physiology 9, 207, 2018 | 35 | 2018 |
| A computational modelling approach combined with cellular electrophysiology data provides insights into the therapeutic benefit of targeting the late Na+ current PC Yang, Y Song, WR Giles, B Horvath, Y Chen‐Izu, L Belardinelli, ... The Journal of physiology 593 (6), 1429-1442, 2015 | 32 | 2015 |
| A computational model of induced pluripotent stem-cell derived cardiomyocytes for high throughput risk stratification of KCNQ1 genetic variants DC Kernik, PC Yang, J Kurokawa, JC Wu, CE Clancy PLoS computational biology 16 (8), e1008109, 2020 | 26 | 2020 |
colleen e. clancyUniversity of California Davisכתובת אימייל מאומתת בדומיין ucdavis.edu