The pathogenesis of sepsis DJ Stearns-Kurosawa, MF Osuchowski, C Valentine, S Kurosawa, ... Annual review of pathology: mechanisms of disease 6 (1), 19-48, 2011 | 824 | 2011 |
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality MF Osuchowski, K Welch, J Siddiqui, DG Remick The Journal of Immunology 177 (3), 1967-1974, 2006 | 758 | 2006 |
Sepsis: multiple abnormalities, heterogeneous responses, and evolving understanding KN Iskander, MF Osuchowski, DJ Stearns-Kurosawa, S Kurosawa, ... Physiological reviews 93 (3), 1247-1288, 2013 | 567 | 2013 |
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity MF Osuchowski, MS Winkler, T Skirecki, S Cajander, M Shankar-Hari, ... The Lancet Respiratory Medicine 9 (6), 622-642, 2021 | 560 | 2021 |
Current gaps in sepsis immunology: new opportunities for translational research I Rubio, MF Osuchowski, M Shankar-Hari, T Skirecki, MS Winkler, ... The Lancet infectious diseases 19 (12), e422-e436, 2019 | 328 | 2019 |
Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): An International Expert Consensus Initiative for Improvement of Animal Modeling in Sepsis FM Osuchowski, A Ayala, S Bahrami, M Bauer, M Boros, JM Cavaillon, ... SHOCK 50 (4), 377-380, 2018 | 288 | 2018 |
The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APPsw mice J Wegiel, KC Wang, H Imaki, R Rubenstein, A Wronska, M Osuchowski, ... Neurobiology of aging 22 (1), 49-61, 2001 | 200 | 2001 |
Abandon the mouse research ship? Not just yet! MF Osuchowski, DG Remick, JA Lederer, CH Lang, AO Aasen, M Aibiki, ... Shock 41 (6), 463-475, 2014 | 181 | 2014 |
Stratification is the key: inflammatory biomarkers accurately direct immunomodulatory therapy in experimental sepsis MF Osuchowski, J Connett, K Welch, J Granger, DG Remick Critical care medicine 37 (5), 1567-1573, 2009 | 172 | 2009 |
Sepsis chronically in MARS: systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis MF Osuchowski, F Craciun, KM Weixelbaumer, ER Duffy, DG Remick The Journal of Immunology 189 (9), 4648-4656, 2012 | 134 | 2012 |
Chronic sepsis mortality characterized by an individualized inflammatory response MF Osuchowski, K Welch, H Yang, J Siddiqui, DG Remick The Journal of Immunology 179 (1), 623-630, 2007 | 107 | 2007 |
Protective role of peroxisome proliferator–activated receptor-β/δ in septic shock A Kapoor, Y Shintani, M Collino, MF Osuchowski, D Busch, NSA Patel, ... American journal of respiratory and critical care medicine 182 (12), 1506-1515, 2010 | 102 | 2010 |
Cecal ligation and puncture-induced murine sepsis does not cause lung injury KN Iskander, FL Craciun, DM Stepien, ER Duffy, J Kim, R Moitra, ... Critical care medicine 41 (1), 159-170, 2013 | 87 | 2013 |
Origin and turnover of microglial cells in fibrillar plaques of APPsw transgenic mice J Wegiel, H Imaki, KC Wang, J Wegiel, A Wronska, M Osuchowski, ... Acta neuropathologica 105, 393-402, 2003 | 79 | 2003 |
Part I: minimum quality threshold in preclinical sepsis studies (MQTiPSS) for study design and humane modeling endpoints B Zingarelli, CM Coopersmith, S Drechsler, P Efron, JC Marshall, ... Shock 51 (1), 10-22, 2019 | 77 | 2019 |
Physiological responses of a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice VJ Johnson, Q He, MF Osuchowski, RP Sharma Planta medica 69 (01), 44-49, 2003 | 73 | 2003 |
SARS-CoV-2/COVID-19: evolving reality, global response, knowledge gaps, and opportunities MF Osuchowski, F Aletti, JM Cavaillon, SB Flohe, ... Shock 54 (4), 416-437, 2020 | 69 | 2020 |
Part II: minimum quality threshold in preclinical sepsis studies (MQTiPSS) for types of infections and organ dysfunction endpoints C Libert, A Ayala, M Bauer, JM Cavaillon, C Deutschman, C Frostell, ... Shock 51 (1), 23-32, 2019 | 66 | 2019 |
Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis S Drechsler, K Weixelbaumer, P Raeven, M Jafarmadar, A Khadem, ... PloS one 7 (12), e51457, 2012 | 62 | 2012 |
Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis S Drechsler, J Zipperle, P Rademann, M Jafarmadar, A Klotz, S Bahrami, ... Scientific reports 8 (1), 14890, 2018 | 60 | 2018 |