| Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice ER Pereira, D Kedrin, G Seano, O Gautier, EFJ Meijer, D Jones, SM Chin, ... Science 359 (6382), 1403-1407, 2018 | 435 | 2018 |
| Normalizing function of tumor vessels: progress, opportunities, and challenges JD Martin, G Seano, RK Jain Annual review of physiology 81 (1), 505-534, 2019 | 426 | 2019 |
| Solid stress and elastic energy as measures of tumour mechanopathology HT Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, ... Nature biomedical engineering 1 (1), 0004, 2016 | 414 | 2016 |
| Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival J Kloepper, L Riedemann, Z Amoozgar, G Seano, K Susek, V Yu, ... Proceedings of the National Academy of Sciences 113 (16), 4476-4481, 2016 | 355 | 2016 |
| Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages TE Peterson, ND Kirkpatrick, Y Huang, CT Farrar, KA Marijt, J Kloepper, ... Proceedings of the National Academy of Sciences 113 (16), 4470-4475, 2016 | 308 | 2016 |
| Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models F Maione, F Molla, C Meda, R Latini, L Zentilin, M Giacca, G Seano, ... The Journal of clinical investigation 119 (11), 3356-3372, 2009 | 266 | 2009 |
| Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients SM Tolaney, Y Boucher, DG Duda, JD Martin, G Seano, M Ancukiewicz, ... Proceedings of the National Academy of Sciences 112 (46), 14325-14330, 2015 | 264 | 2015 |
| A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment A Griveau, G Seano, SJ Shelton, R Kupp, A Jahangiri, K Obernier, ... Cancer cell 33 (5), 874-889. e7, 2018 | 238 | 2018 |
| Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery M Datta, LE Via, WS Kamoun, C Liu, W Chen, G Seano, DM Weiner, ... Proceedings of the National Academy of Sciences 112 (6), 1827-1832, 2015 | 221 | 2015 |
| Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium G Seano, HT Nia, KE Emblem, M Datta, J Ren, S Krishnan, J Kloepper, ... Nature biomedical engineering 3 (3), 230-245, 2019 | 192 | 2019 |
| Challenges in glioblastoma research: focus on the tumor microenvironment A Bikfalvi, CA da Costa, T Avril, JV Barnier, L Bauchet, L Brisson, ... Trends in cancer 9 (1), 9-27, 2023 | 166 | 2023 |
| Vessel co-option in glioblastoma: emerging insights and opportunities G Seano, RK Jain Angiogenesis 23 (1), 9-16, 2020 | 142 | 2020 |
| Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, A Puliafito, C Bouvard, ... Nature cell biology 16 (10), 931-941, 2014 | 135 | 2014 |
| Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy EI Ager, SV Kozin, ND Kirkpatrick, G Seano, DP Kodack, V Askoxylakis, ... Journal of the National Cancer Institute 107 (4), djv017, 2015 | 128 | 2015 |
| The miR-126 regulates angiopoietin-1 signaling and vessel maturation by targeting p85β R Sessa, G Seano, L di Blasio, PA Gagliardi, C Isella, E Medico, F Cotelli, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (10), 1925-1935, 2012 | 112 | 2012 |
| Quantifying solid stress and elastic energy from excised or in situ tumors HT Nia, M Datta, G Seano, P Huang, LL Munn, RK Jain Nature protocols 13 (5), 1091-1105, 2018 | 94 | 2018 |
| Preclinical efficacy of ado-trastuzumab emtansine in the brain microenvironment V Askoxylakis, GB Ferraro, DP Kodack, M Badeaux, RC Shankaraiah, ... Journal of the National Cancer Institute 108 (2), djv313, 2016 | 89 | 2016 |
| Modeling human tumor angiogenesis in a three-dimensional culture system G Seano, G Chiaverina, PA Gagliardi, L Di Blasio, R Sessa, F Bussolino, ... Blood, The Journal of the American Society of Hematology 121 (21), e129-e137, 2013 | 85 | 2013 |
| Increased expression of α6 integrin in endothelial cells unveils a proangiogenic role for basement membrane L Primo, G Seano, C Roca, F Maione, PA Gagliardi, R Sessa, M Martinelli, ... Cancer research 70 (14), 5759-5769, 2010 | 82 | 2010 |
| 3-phosphoinositide-dependent kinase 1 controls breast tumor growth in a kinase-dependent but Akt-independent manner PA Gagliardi, L di Blasio, F Orso, G Seano, R Sessa, D Taverna, ... Neoplasia 14 (8), 719-IN19, 2012 | 79 | 2012 |
Rakesh K JainHarvard Medical School, Carnegie Mellon, Columbia, Delaware
