עקוב אחר
Philip J.Y. Leung
Philip J.Y. Leung
Xaira Therapeutics
כתובת אימייל מאומתת בדומיין xaira.com - דף הבית
כותרת
צוטט על ידי
צוטט על ידי
שנה
Robust deep learning–based protein sequence design using ProteinMPNN‏
J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ...‏
Science 378 (6615), 49-56, 2022‏
10582022
De novo design of high-affinity binders of bioactive helical peptides‏
S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ...‏
Nature 626 (7998), 435-442, 2024‏
872024
Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics‏
EA Nalefski, N Patel, PJY Leung, Z Islam, RM Kooistra, I Parikh, E Marion, ...‏
Iscience 24 (9), 2021‏
732021
Atomically accurate de novo design of single-domain antibodies‏
NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ...‏
bioRxiv, 2024‏
602024
Design of stimulus-responsive two-state hinge proteins‏
F Praetorius, PJY Leung, MH Tessmer, A Broerman, C Demakis, ...‏
Science 381 (6659), 754-760, 2023‏
352023
Blueprinting extendable nanomaterials with standardized protein blocks‏
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...‏
Nature 627 (8005), 898-904, 2024‏
302024
De novo design of allosterically switchable protein assemblies‏
A Pillai, A Idris, A Philomin, C Weidle, R Skotheim, PJY Leung, ...‏
Nature 632 (8026), 911-920, 2024‏
292024
De novo design of high-affinity protein binders to bioactive helical peptides‏
SV Torres, PJY Leung, ID Lutz, P Venkatesh, JL Watson, F Hink, ...‏
bioRxiv, 2022.12. 10.519862, 2022‏
212022
Blueprinting expandable nanomaterials with standardized protein building blocks‏
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...‏
bioRxiv, 2023.06. 09.544258, 2023‏
22023
LEARNING LIGHTWEIGHT STRUCTURE-AWARE EMBEDDINGS FOR PROTEIN SEQUENCES‏
S Lakshmanan, PJY Leung, J Nivala‏
2023
De design de novo de mudanças conformacionais proteicas e interações proteicas-peptídeos‏
PJY Leung‏
2023
De Novo Design of Protein Conformational Changes and Protein-Peptide Interactions‏
P Leung‏
University of Washington, 2023‏
2023
De Novo Design of Conformationally Dynamic Proteins‏
A Broerman, F Praetorius, P Leung, C Demakis, D Juergens, M Tessmer, ...‏
PROTEIN SCIENCE 32, 2023‏
2023
De novo design of protein binders for peptide recognition‏
SV Torres, I Lutz, P Leung, J Watson, M MacCoss, D Baker‏
PROTEIN SCIENCE 32, 2023‏
2023
Solution-phase, trans-activated reporter systems for use in crispr-based nucleic acid sequence detections‏
T Baughman, ALM Le Ny, P Leung, D Madan, E Nalefski‏
US Patent App. 17/430,235, 2022‏
2022
A GENERATIVE ALGORITHM FOR PROTEINS FROM THE NTF2-LIKE SUPERFAMILY‏
B Basanta, M Bick, T Baughman, P Leung, E Nalefski, D Baker‏
PROTEIN SCIENCE 28, 64-65, 2019‏
2019
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מאמרים 1–16