Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson’s disease O Cooper, H Seo, S Andrabi, C Guardia-Laguarta, J Graziotto, ... Science translational medicine 4 (141), 141ra90-141ra90, 2012 | 567 | 2012 |
Personalized iPSC-derived dopamine progenitor cells for Parkinson’s disease JS Schweitzer, B Song, TM Herrington, TY Park, N Lee, S Ko, J Jeon, ... New England Journal of Medicine 382 (20), 1926-1932, 2020 | 451 | 2020 |
Cell type-specific gene expression of midbrain dopaminergic neurons reveals molecules involved in their vulnerability and protection CY Chung, H Seo, KC Sonntag, A Brooks, L Lin, O Isacson Human molecular genetics 14 (13), 1709-1725, 2005 | 450 | 2005 |
Orphan nuclear receptor Nurr1 directly transactivates the promoter activity of the tyrosine hydroxylase gene in a cell‐specific manner KS Kim, CH Kim, DY Hwang, H Seo, S Chung, SJ Hong, JK Lim, ... Journal of neurochemistry 85 (3), 622-634, 2003 | 241 | 2003 |
Alzheimer's disease and Down's syndrome: roles of APP, trophic factors and ACh O Isacson, H Seo, L Lin, D Albeck, AC Granholm TRENDS in Neurosciences 25 (2), 79-84, 2002 | 235 | 2002 |
Dual‐specificity tyrosine (Y)‐phosphorylation regulated kinase 1A‐mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome … SR Ryoo, HJ Cho, HW Lee, HK Jeong, C Radnaabazar, YS Kim, MJ Kim, ... Journal of neurochemistry 104 (5), 1333-1344, 2008 | 229 | 2008 |
Generalized brain and skin proteasome inhibition in Huntington's disease H Seo, KC Sonntag, O Isacson Annals of neurology 56 (3), 319-328, 2004 | 223 | 2004 |
Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain H Noh, J Jeon, H Seo Neurochemistry international 69, 35-40, 2014 | 218 | 2014 |
Efficient induction of oligodendrocytes from human embryonic stem cells SM Kang, MS Cho, H Seo, CJ Yoon, SK Oh, YM Choi, DW Kim Stem Cells 25 (2), 419-424, 2007 | 175 | 2007 |
Proteasome activator enhances survival of Huntington's disease neuronal model cells H Seo, KC Sonntag, W Kim, E Cattaneo, O Isacson PloS one 2 (2), e238, 2007 | 166 | 2007 |
Paired‐Like Homeodomain Proteins, Phox2a and Phox2b, Are Responsible for Noradrenergic Cell‐Specific Transcription of the Dopamine β‐Hydroxylase Gene C Yang, HS Kim, H Seo, CH Kim, JF Brunet, KS Kim Journal of neurochemistry 71 (5), 1813-1826, 1998 | 165 | 1998 |
miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling W Kim, Y Lee, ND McKenna, M Yi, F Simunovic, Y Wang, B Kong, ... Neurobiology of aging 35 (7), 1712-1721, 2014 | 161 | 2014 |
Human autologous iPSC–derived dopaminergic progenitors restore motor function in Parkinson’s disease models B Song, Y Cha, S Ko, J Jeon, N Lee, H Seo, KJ Park, IH Lee, C Lopes, ... The Journal of clinical investigation 130 (2), 904-920, 2020 | 157 | 2020 |
Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells J Park, Y Oh, L Yoo, MS Jung, WJ Song, SH Lee, H Seo, KC Chung Journal of Biological Chemistry 285 (41), 31895-31906, 2010 | 155 | 2010 |
Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice H Seo, O Isacson Experimental neurology 193 (2), 469-480, 2005 | 149 | 2005 |
Noradrenergic-Specific Transcription of the Dopamine β-Hydroxylase Gene Requires Synergy of MultipleCis-Acting Elements Including at Least Two Phox2a-Binding Sites HS Kim, H Seo, C Yang, JF Brunet, KS Kim Journal of Neuroscience 18 (20), 8247-8260, 1998 | 147 | 1998 |
Increased DJ‐1 in urine exosome of Korean males with Parkinson’s disease DH Ho, S Yi, H Seo, I Son, W Seol BioMed research international 2014 (1), 704678, 2014 | 116 | 2014 |
LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase I Choi, B Kim, JW Byun, SH Baik, YH Huh, JH Kim, I Mook-Jung, WK Song, ... Nature Communications 6 (1), 8255, 2015 | 112 | 2015 |
Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington’s disease C Hong, H Seo, M Kwak, J Jeon, J Jang, EM Jeong, J Myeong, YJ Hwang, ... Brain 138 (10), 3030-3047, 2015 | 107 | 2015 |
Structure/function relationship of the cAMP response element in tyrosine hydroxylase gene transcription C Tinti, C Yang, H Seo, B Conti, C Kim, TH Joh, KS Kim Journal of Biological Chemistry 272 (31), 19158-19164, 1997 | 98 | 1997 |