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Optimization of ligands using focused DNA-encoded libraries to develop a selective, cell-permeable CBX8 chromodomain inhibitor S Wang, KE Denton, KF Hobbs, T Weaver, JMB McFarlane, KE Connelly, ... ACS chemical biology 15 (1), 112-131, 2019 | 68 | 2019 |
Robustness of in vitro selection assays of DNA-encoded peptidomimetic ligands to CBX7 and CBX8 KE Denton, S Wang, MC Gignac, N Milosevich, F Hof, EC Dykhuizen, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 23 (5), 417-428, 2018 | 56 | 2018 |
A potent, selective CBX2 chromodomain ligand and its cellular activity during prostate cancer neuroendocrine differentiation S Wang, A Alpsoy, S Sood, SC Ordonez‐Rubiano, A Dhiman, Y Sun, ... Chembiochem 22 (13), 2335-2344, 2021 | 36 | 2021 |
Polycomb group proteins in cancer: multifaceted functions and strategies for modulation S Wang, S C. Ordonez-Rubiano, A Dhiman, G Jiao, BP Strohmier, ... NAR cancer 3 (4), zcab039, 2021 | 14 | 2021 |
Polycomb paralog chromodomain inhibitors active against both CBX6 and CBX8 N Milosevich, CR Wilson, TM Brown, A Alpsoy, S Wang, KE Connelly, ... ChemMedChem 16 (19), 3027-3034, 2021 | 10 | 2021 |
Rational design and development of selective BRD7 bromodomain inhibitors and their activity in prostate cancer SC Ordonez-Rubiano, CA Maschinot, S Wang, S Sood, ... Journal of medicinal chemistry 66 (16), 11250-11270, 2023 | 7 | 2023 |
Development of Oxadiazolone Activity-Based Probes Targeting FphE for Specific Detection of Staphylococcus aureus Infections J Jo, T Upadhyay, EC Woods, KW Park, NJ Pedowitz, ... Journal of the American Chemical Society 146 (10), 6880-6892, 2024 | 6 | 2024 |
Covalent protein inhibitors via tyrosine conjugation with cyclic imine mannich electrophiles S Wang, M Hadisurya, WA Tao, E Dykhuizen, C Krusemark | 4 | 2022 |
Discovery of Thioether-Cyclized Macrocyclic Covalent Inhibitors by mRNA Display T Lan, C Peng, X Yao, RST Chan, T Wei, A Rupanya, A Radakovic, ... Journal of the American Chemical Society 146 (34), 24053-24060, 2024 | 3 | 2024 |
Identification of covalent cyclic peptide inhibitors targeting protein-protein interactions using phage display S Wang, FF Faucher, M Bertolini, H Kim, B Yu, L Cao, K Roeltgen, ... bioRxiv, 2024.11. 08.622749, 2024 | 1 | 2024 |
An mRNA Display Approach for Covalent Targeting of a Staphylococcus aureus Virulence Factor S Wang, EC Woods, J Jo, J Zhu, A Hansel-Harris, M Holcomb, ... bioRxiv, 2024 | | 2024 |
New approaches and applications with DNA-encoded chemicals: Ligand discovery and activity-based probes C Krusemark, B Peters, B Cai, Y Sun, S Wang American Chemical Society SciMeetings 1 (2), 2020 | | 2020 |
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