| Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy R Ravi, KA Noonan, V Pham, R Bedi, A Zhavoronkov, IV Ozerov, ... Nature communications 9 (1), 741, 2018 | 314 | 2018 |
| Machine learning on human muscle transcriptomic data for biomarker discovery and tissue-specific drug target identification P Mamoshina, M Volosnikova, IV Ozerov, E Putin, E Skibina, F Cortese, ... Frontiers in genetics 9, 242, 2018 | 208 | 2018 |
| AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ... Chemical Science 14 (6), 1443-1452, 2023 | 192 | 2023 |
| AI-powered therapeutic target discovery FW Pun, IV Ozerov, A Zhavoronkov Trends in pharmacological sciences 44 (9), 561-572, 2023 | 169 | 2023 |
| In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development IV Ozerov, KV Lezhnina, E Izumchenko, AV Artemov, S Medintsev, ... Nature communications 7 (1), 13427, 2016 | 161 | 2016 |
| Design of efficient computational workflows for in silico drug repurposing Q Vanhaelen, P Mamoshina, AM Aliper, A Artemov, K Lezhnina, I Ozerov, ... Drug Discovery Today 22 (2), 210-222, 2017 | 157 | 2017 |
| Vive la radiorésistance!: converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization F Cortese, D Klokov, A Osipov, J Stefaniak, A Moskalev, J Schastnaya, ... Oncotarget 9 (18), 14692, 2018 | 104 | 2018 |
| Immune profiles in primary squamous cell carcinoma of the head and neck V Saloura, E Izumchenko, Z Zuo, R Bao, M Korzinkin, I Ozerov, ... Oral Oncology 96, 77-88, 2019 | 76 | 2019 |
| A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe, IV Ozerov, M Zhang, ... Nature Biotechnology, 1-13, 2024 | 75 | 2024 |
| Identification of therapeutic targets for amyotrophic lateral sclerosis using PandaOmics–an AI-enabled biological target discovery platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in aging neuroscience 14, 914017, 2022 | 75 | 2022 |
| Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 68 | 2022 |
| Activation of homologous recombination DNA repair in human skin fibroblasts continuously exposed to X-ray radiation AN Osipov, A Grekhova, M Pustovalova, IV Ozerov, P Eremin, ... Oncotarget 6 (29), 26876, 2015 | 54 | 2015 |
| Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells M Pustovalova, ТA Astrelina, A Grekhova, N Vorobyeva, A Tsvetkova, ... Aging (Albany NY) 9 (11), 2397, 2017 | 53 | 2017 |
| γH2AX, 53BP1 and Rad51 protein foci changes in mesenchymal stem cells during prolonged X-ray irradiation A Tsvetkova, IV Ozerov, M Pustovalova, A Grekhova, P Eremin, ... Oncotarget 8 (38), 64317, 2017 | 51 | 2017 |
| Changes in the number of double-strand DNA breaks in Chinese hamster V79 cells exposed to γ-radiation with different dose rates KV Kotenko, AY Bushmanov, IV Ozerov, DV Guryev, NA Anchishkina, ... International journal of molecular sciences 14 (7), 13719-13726, 2013 | 50 | 2013 |
| Diffuse colonies of human skin fibroblasts in relation to cellular senescence and proliferation V Zorin, A Zorina, N Smetanina, P Kopnin, IV Ozerov, S Leonov, A Isaev, ... Aging (albany NY) 9 (5), 1404, 2017 | 45 | 2017 |
| In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia E Makarev, AD Schubert, RR Kanherkar, N London, M Teka, I Ozerov, ... Cell death discovery 3 (1), 1-7, 2017 | 37 | 2017 |
| Accumulation of spontaneous γH2AX foci in long-term cultured mesenchymal stromal cells M Pustovalova, A Grekhova, T Astrelina, V Nikitina, E Dobrovolskaya, ... Aging (Albany NY) 8 (12), 3498, 2016 | 37 | 2016 |
| New function of the myostatin/activin type I receptor (ALK4) as a mediator of muscle atrophy and muscle regeneration S Pasteuning-Vuhman, JW Boertje-van der Meulen, M Van Putten, ... The FASEB Journal 31 (1), 238, 2016 | 37 | 2016 |
| PandaOmics: an AI-driven platform for therapeutic target and biomarker discovery P Kamya, IV Ozerov, FW Pun, K Tretina, T Fokina, S Chen, V Naumov, ... Journal of chemical information and modeling 64 (10), 3961-3969, 2024 | 35 | 2024 |
Alex Zhavoronkov (Aleksandrs Zavoro...Insilico Medicineכתובת אימייל מאומתת בדומיין insilico.com