sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance A Kaur, MR Webster, K Marchbank, R Behera, A Ndoye, CH Kugel, ... Nature 532 (7598), 250-254, 2016 | 398 | 2016 |
Remodeling of the collagen matrix in aging skin promotes melanoma metastasis and affects immune cell motility A Kaur, BL Ecker, SM Douglass, CH Kugel III, MR Webster, FV Almeida, ... Cancer discovery 9 (1), 64-81, 2019 | 364 | 2019 |
Age correlates with response to anti-PD1, reflecting age-related differences in intratumoral effector and regulatory T-cell populations CH Kugel III, SM Douglass, MR Webster, A Kaur, Q Liu, X Yin, SA Weiss, ... Clinical Cancer Research 24 (21), 5347-5356, 2018 | 344 | 2018 |
Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2 MP O'Connell, K Marchbank, MR Webster, AA Valiga, A Kaur, A Vultur, ... Cancer discovery 3 (12), 1378-1393, 2013 | 260 | 2013 |
Plasma markers of disrupted gut permeability in severe COVID-19 patients LB Giron, H Dweep, X Yin, H Wang, M Damra, AR Goldman, N Gorman, ... Frontiers in immunology 12, 686240, 2021 | 172 | 2021 |
BET inhibitors suppress ALDH activity by targeting ALDH1A1 super-enhancer in ovarian cancer Y Yokoyama, H Zhu, JH Lee, AV Kossenkov, SY Wu, JM Wickramasinghe, ... Cancer research 76 (21), 6320-6330, 2016 | 150 | 2016 |
A comprehensive patient-derived xenograft collection representing the heterogeneity of melanoma C Krepler, K Sproesser, P Brafford, M Beqiri, B Garman, M Xiao, ... Cell reports 21 (7), 1953-1967, 2017 | 140 | 2017 |
Evaluation of drug combination effect using a bliss independence dose–response surface model Q Liu, X Yin, LR Languino, DC Altieri Statistics in biopharmaceutical research 10 (2), 112-122, 2018 | 138 | 2018 |
Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma IM Echevarría‐Vargas, PI Reyes‐Uribe, AN Guterres, X Yin, ... EMBO molecular medicine 10 (5), e8446, 2018 | 96 | 2018 |
Genetic and genomic characterization of 462 melanoma patient-derived xenografts, tumor biopsies, and cell lines B Garman, IN Anastopoulos, C Krepler, P Brafford, K Sproesser, Y Jiang, ... Cell reports 21 (7), 1936-1952, 2017 | 78 | 2017 |
Paradoxical role for wild-type p53 in driving therapy resistance in melanoma MR Webster, ME Fane, GM Alicea, S Basu, AV Kossenkov, GE Marino, ... Molecular cell 77 (3), 633-644. e5, 2020 | 70 | 2020 |
Natural Killer Cell Activation Distinguishes Mycobacterium tuberculosis–Mediated Immune Reconstitution Syndrome From Chronic HIV and HIV/MTB Coinfection F Conradie, AS Foulkes, P Ive, X Yin, K Roussos, DK Glencross, D Lawrie, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 58 (3), 309-318, 2011 | 70 | 2011 |
Anti–CTLA-4 activates intratumoral NK cells and combined with IL15/IL15Rα complexes enhances tumor control E Sanseviero, EM O’Brien, JR Karras, TB Shabaneh, BA Aksoy, W Xu, ... Cancer immunology research 7 (8), 1371-1380, 2019 | 67 | 2019 |
High-risk oncogenic HPV genotype infection associates with increased immune activation and T cell exhaustion in ART-suppressed HIV-1-infected women E Papasavvas, LF Surrey, DK Glencross, L Azzoni, J Joseph, T Omar, ... Oncoimmunology 5 (5), e1128612, 2016 | 46 | 2016 |
Increased microbial translocation in≤ 180 days old perinatally human immunodeficiency virus-positive infants as compared with human immunodeficiency virus-exposed uninfected … E Papasavvas, L Azzoni, A Foulkes, A Violari, MF Cotton, M Pistilli, ... The Pediatric infectious disease journal 30 (10), 877-882, 2011 | 46 | 2011 |
Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV LB Giron, CS Palmer, Q Liu, X Yin, E Papasavvas, R Sharaf, B Etemad, ... Nature communications 12 (1), 3922, 2021 | 44 | 2021 |
Induction of telomere dysfunction prolongs disease control of therapy-resistant melanoma G Zhang, LW Wu, I Mender, M Barzily-Rokni, MR Hammond, O Ope, ... Clinical Cancer Research 24 (19), 4771-4784, 2018 | 41 | 2018 |
The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged RK Kurupati, A Kossenkoff, S Kannan, LH Haut, S Doyle, X Yin, ... Vaccine 35 (30), 3700-3708, 2017 | 39 | 2017 |
HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes SA Abdulhaqq, C Zorrilla, G Kang, X Yin, V Tamayo, KE Seaton, J Joseph, ... Mucosal immunology 9 (4), 1027-1038, 2016 | 39 | 2016 |
HSP70 inhibition limits FAK-dependent invasion and enhances the response to melanoma treatment with BRAF inhibitors A Budina-Kolomets, MR Webster, JIJ Leu, M Jennis, C Krepler, A Guerrini, ... Cancer research 76 (9), 2720-2730, 2016 | 39 | 2016 |