Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelles ER Kuechler, PM Budzyńska, JP Bernardini, J Gsponer, T Mayor Journal of Molecular Biology 432 (7), 2349-2368, 2020 | 76 | 2020 |
A variational linear-scaling framework to build practical, efficient next-generation orbital-based quantum force fields TJ Giese, H Chen, T Dissanayake, GM Giambasu, H Heldenbrand, ... Journal of chemical theory and computation 9 (3), 1417-1427, 2013 | 69 | 2013 |
Protein–Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations ETC Wong, V So, M Guron, ER Kuechler, N Malhis, JM Bui, J Gsponer Biomolecules 10 (8), 1097, 2020 | 33 | 2020 |
Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules M Zhu, ER Kuechler, J Zhang, O Matalon, B Dubreuil, A Hofmann, ... Journal of Cell Science 133 (13), 244657, 2020 | 30 | 2020 |
Charge-dependent many-body exchange and dispersion interactions in combined QM/MM simulations ER Kuechler, TJ Giese, DM York The Journal of Chemical Physics 143 (23), 2015 | 29 | 2015 |
Multiscale methods for computational RNA enzymology MT Panteva, T Dissanayake, H Chen, BK Radak, ER Kuechler, ... Methods in enzymology 553, 335-374, 2015 | 29 | 2015 |
Quantum mechanical study of solvent effects in a prototype SN2 reaction in solution: Cl− attack on CH3Cl ER Kuechler, DM York The Journal of Chemical Physics 140 (5), 2014 | 24 | 2014 |
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ... Cell reports 42 (5), 2023 | 21 | 2023 |
GraPES: The Granule Protein Enrichment Server for prediction of biological condensate constituents ER Kuechler, M Jacobson, T Mayor, J Gsponer Nucleic Acids Research 50 (W1), W384-W391, 2022 | 14 | 2022 |
A multidimensional B-spline correction for accurate modeling sugar puckering in QM/MM simulations M Huang, T Dissanayake, E Kuechler, BK Radak, TS Lee, TJ Giese, ... Journal of chemical theory and computation 13 (9), 3975-3984, 2017 | 13 | 2017 |
Pulse labeling reveals the tail end of protein folding by proteome profiling M Zhu, ER Kuechler, RWK Wong, G Calabrese, IM Sitarik, V Rana, ... Cell reports 40 (3), 2022 | 11 | 2022 |
Shift of the insoluble content of the proteome in the aging mouse brain C Molzahn, ER Kuechler, I Zemlyankina, L Nierves, T Ali, G Cole, J Wang, ... Proceedings of the National Academy of Sciences 120 (45), e2310057120, 2023 | 9 | 2023 |
Comparison of biomolecular condensate localization and protein phase separation predictors ER Kuechler, A Huang, JM Bui, T Mayor, J Gsponer Biomolecules 13 (3), 527, 2023 | 7 | 2023 |
VR-SCOSMO: A smooth conductor-like screening model with charge-dependent radii for modeling chemical reactions ER Kuechler, TJ Giese, DM York The Journal of Chemical Physics 144 (16), 2016 | 5 | 2016 |
Protein feature analysis of heat shock induced ubiquitination sites reveals preferential modification site localization ER Kuechler, A Rose, M Bolten, A Madero, S Kammoonah, S Colborne, ... Journal of Proteomics 239, 104182, 2021 | 4 | 2021 |
Proteomic analysis reveals the recruitment of intrinsically disordered regions to stress granules M Zhu, ER Kuechler, J Zhang, O Matalon, B Dubreuil, A Hofmann, ... BioRxiv, 758599, 2019 | 2 | 2019 |
Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by aging C Molzahn, E Kuechler, L Nierves, G Cole, J Wang, N Cashman, ... bioRxiv, 2024.02. 28.582597, 2024 | | 2024 |
Stress Granule Protein Features Allow for Accurate Prediction of Biological Condensate Localization with GraPES E Kuechler, J Gsponer, T Mayor The FASEB Journal 35, 2021 | | 2021 |
Self-consistent charge-dependent interaction models for use in condensed phase molecular simulation E Kuechler, T Giese, D York ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Charge-dependent non-bonded interaction methods for use in quantum mechanical modeling of condensed phase reactions ER Kuechler University of Minnesota, 2015 | | 2015 |