עקוב אחר
Pierre De Meyts, MD, PhD
Pierre De Meyts, MD, PhD
Visiting professor, de Duve Institute
כתובת אימייל מאומתת בדומיין novonordisk.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture
JR Gavin III, J Roth, DM Neville Jr, P De Meyts, DN Buell
Proceedings of the National Academy of Sciences 71 (1), 84-88, 1974
14301974
Insulin interactions with its receptors: experimental evidence for negative cooperativity
P De Meyts, J Roth, DM Neville Jr, JR Gavin III, MA Lesniak
Biochemical and biophysical research communications 55 (1), 154-161, 1973
8551973
Structural biology of insulin and IGF1 receptors: implications for drug design
P De Meyts, J Whittaker
Nature reviews Drug discovery 1 (10), 769-783, 2002
7832002
Site-site interactions among insulin receptors: characterization of the negative cooperativity.
DE Meyts P, B AR, R J
Journal of Biological Chemistry 251, 1877-1888, 1976
7741976
Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting.
RS Bar, P Gorden, J Roth, CR Kahn, P De Meyts
The Journal of clinical investigation 58 (5), 1123-1135, 1976
5861976
Cooperativity in ligand binding: a new graphic analysis
P De Meyts, J Roth
Biochemical and biophysical research communications 66 (4), 1118-1126, 1975
4871975
Insulin and its receptor: structure, function and evolution
P De Meyts
Bioessays 26 (12), 1351-1362, 2004
4612004
The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling
P De Meyts
Diabetologia 37 (Suppl 2), S135-S148, 1994
3491994
The insulin receptor and its signal transduction network
P De Meyts
Endotext [Internet], 2016
3122016
The insulin-like growth factor-I receptor: structure, ligand-binding mechanism and signal transduction
P De Meyts, B Wallach, CT Christoffersen, B Ursø, K Grønskov, LJ Latus, ...
Hormone Research in Paediatrics 42 (4-5), 152-169, 1994
3111994
Alterations in insulin binding induced by changes in vivo in the levels of glucocorticoids and growth hormone
C RONALD KAHN, IRAD GOLDFINE, DM NEVILLE JR, P DE MEYTS
Endocrinology 103 (4), 1054-1066, 1978
3101978
Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin
PD Meyts, E Van Obberghen, J Roth, A Wollmer, D Brandenburg
Nature 273 (5663), 504-509, 1978
2611978
Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man
J ROTH, CR KAHN, MA LESNIAK, P GORDEN, P DE MEYTS, ...
Proceedings of the 1974 Laurentian Hormone Conference, 95-139, 1975
2531975
Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor
D Ish-Shalom, CT Christoffersen, P Vorwerk, N Sacerdoti-Sierra, ...
Diabetologia 40, S25-S31, 1997
2511997
β-Adrenergic receptors: evidence for negative cooperativity
LE Limbird, P De Meyts, RJ Lefkowitz
Biochemical and biophysical research communications 64 (4), 1160-1168, 1975
2421975
Cooperative properties of hormone receptors in cell membranes
PD Meyts
Journal of Supramolecular Structure 4 (2), 241-258, 1976
2221976
The insulin receptor: a prototype for dimeric, allosteric membrane receptors?
P De Meyts
Trends in biochemical sciences 33 (8), 376-384, 2008
2152008
The insulin receptor in vertebrates is functionally more conserved during evolution than insulin itself
M MUGGEO, BH GINSBERG, J ROTH, DM NEVILLE JR, PDE MEYTS, ...
Endocrinology 104 (5), 1393-1402, 1979
2101979
Harmonic oscillator model of the insulin and IGF1 receptors’ allosteric binding and activation
VV Kiselyov, S Versteyhe, L Gauguin, P De Meyts
Molecular systems biology 5 (1), 243, 2009
2062009
A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum
JW Chen, T Ledet, H Ørskov, N Jessen, S Lund, J Whittaker, P De Meyts, ...
American Journal of Physiology-Endocrinology and Metabolism 284 (6), E1149-E1155, 2003
1852003
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מאמרים 1–20