עקוב אחר
Jon Clardy
Jon Clardy
Professor of Biological Chemistry, Harvard Medical School
כתובת אימייל מאומתת בדומיין hms.harvard.edu
כותרת
צוטט על ידי
צוטט על ידי
שנה
Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products
J Handelsman, MR Rondon, SF Brady, J Clardy, RM Goodman
Chemistry & biology 5 (10), R245-R249, 1998
29371998
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ...
Natural product reports 30 (1), 108-160, 2013
22132013
Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms
MR Rondon, PR August, AD Bettermann, SF Brady, TH Grossman, ...
Applied and environmental microbiology 66 (6), 2541-2547, 2000
17612000
Lessons from natural molecules
J Clardy, C Walsh
Nature 432 (7019), 829-837, 2004
16382004
Atomic structures of the human immunophilin FKBP-12 complexes with FK506 and rapamycin
GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy
Journal of molecular biology 229 (1), 105-124, 1993
14641993
Structure of the FKBP12-rapamycin complex interacting with binding domain of human FRAP
J Choi, J Chen, SL Schreiber, J Clardy
Science 273 (5272), 239-242, 1996
11661996
D-amino acids trigger biofilm disassembly
I Kolodkin-Gal, D Romero, S Cao, J Clardy, R Kolter, R Losick
Science 328 (5978), 627-629, 2010
10802010
Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria
K Tachibana, PJ Scheuer, Y Tsukitani, H Kikuchi, D Van Engen, J Clardy, ...
Journal of the American Chemical Society 103 (9), 2469-2471, 1981
10741981
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters
P Cimermancic, MH Medema, J Claesen, K Kurita, LCW Brown, ...
Cell 158 (2), 412-421, 2014
10462014
Target identification using drug affinity responsive target stability (DARTS)
B Lomenick, R Hao, N Jonai, RM Chin, M Aghajan, S Warburton, J Wang, ...
Proceedings of the National Academy of Sciences 106 (51), 21984-21989, 2009
10152009
Isolation and structure of bryostatin 1
GR Pettit, CL Herald, DL Doubek, DL Herald, E Arnold, J Clardy
Journal of the American Chemical Society 104 (24), 6846-6848, 1982
9751982
GABA-modulating bacteria of the human gut microbiota
P Strandwitz, KH Kim, D Terekhova, JK Liu, A Sharma, J Levering, ...
Nature microbiology 4 (3), 396-403, 2019
9712019
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
9342015
Diarrhetic shellfish toxins
T Yasumoto, M Murata, Y Oshima, M Sano, GK Matsumoto, J Clardy
Tetrahedron 41 (6), 1019-1025, 1985
8811985
New antibiotics from bacterial natural products
J Clardy, MA Fischbach, CT Walsh
Nature biotechnology 24 (12), 1541-1550, 2006
8042006
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex
GD Van Duyne, RF Standaert, PA Karplus, SL Schreiber, J Clardy
Science 252 (5007), 839-842, 1991
7871991
Isolation and structure of brevetoxin B from the" red tide" dinoflagellate Ptychodiscus brevis (Gymnodinium breve)
YY Lin, M Risk, SM Ray, D Van Engen, J Clardy, J Golik, JC James, ...
Journal of the American Chemical Society 103 (22), 6773-6775, 1981
7351981
A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics
MS Donia, P Cimermancic, CJ Schulze, LCW Brown, J Martin, M Mitreva, ...
Cell 158 (6), 1402-1414, 2014
7252014
Isolation of antibiotics turbomycin A and B from a metagenomic library of soil microbial DNA
DE Gillespie, SF Brady, AD Bettermann, NP Cianciotto, MR Liles, ...
Applied and environmental microbiology 68 (9), 4301-4306, 2002
7252002
Ruminococcus gnavus, a member of the human gut microbiome associated with Crohn’s disease, produces an inflammatory polysaccharide
MT Henke, DJ Kenny, CD Cassilly, H Vlamakis, RJ Xavier, J Clardy
Proceedings of the National Academy of Sciences 116 (26), 12672-12677, 2019
7082019
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מאמרים 1–20