TRIM proteins and their roles in antiviral host defenses M van Gent, KMJ Sparrer, MU Gack Annual review of virology 5 (1), 385-405, 2018 | 317 | 2018 |
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ... Nature microbiology 6 (4), 467-478, 2021 | 274 | 2021 |
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity JJ Chiang, KMJ Sparrer, M van Gent, C Lässig, T Huang, N Osterrieder, ... Nature immunology 19 (1), 53-62, 2018 | 247 | 2018 |
Topology and membrane anchoring of the coronavirus replication complex: not all hydrophobic domains of nsp3 and nsp6 are membrane spanning M Oostra, MC Hagemeijer, M van Gent, CPJ Bekker, EG te Lintelo, ... Journal of virology 82 (24), 12392-12405, 2008 | 205 | 2008 |
Immune evasion by Epstein-Barr virus ME Ressing, M van Gent, AM Gram, MJG Hooykaas, SJ Piersma, ... Epstein Barr Virus Volume 2: One Herpes Virus: Many Diseases, 355-381, 2015 | 175 | 2015 |
Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling M van Gent, SGE Braem, A de Jong, N Delagic, JGC Peeters, IGJ Boer, ... PLoS pathogens 10 (2), e1003960, 2014 | 170 | 2014 |
EBV lytic-phase protein BGLF5 contributes to TLR9 downregulation during productive infection M van Gent, BD Griffin, EG Berkhoff, D van Leeuwen, IGJ Boer, M Buisson, ... The Journal of Immunology 186 (3), 1694-1702, 2011 | 118 | 2011 |
EBV microrna BART16 suppresses type I ifn signaling MJG Hooykaas, M Van Gent, JA Soppe, E Kruse, IGJ Boer, D Van Leenen, ... The Journal of Immunology 198 (10), 4062-4073, 2017 | 100 | 2017 |
Human CD45 is an F-component-specific receptor for the staphylococcal toxin Panton–Valentine leukocidin AT Tromp, M Van Gent, P Abrial, A Martin, JP Jansen, CJC De Haas, ... Nature microbiology 3 (6), 708-717, 2018 | 94 | 2018 |
A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase KD Buchan, TK Prajsnar, NV Ogryzko, NWM De Jong, M Van Gent, ... PLoS One 14 (4), e0215592, 2019 | 63 | 2019 |
Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity F Full, M van Gent, KMJ Sparrer, C Chiang, MA Zurenski, M Scherer, ... Nature microbiology 4 (1), 164-176, 2019 | 51 | 2019 |
High-throughput RNA sequencing of paraformaldehyde-fixed single cells HV Phan, M van Gent, N Drayman, A Basu, MU Gack, S Tay Nature Communications 12 (1), 5636, 2021 | 48 | 2021 |
Silencing the shutoff protein of Epstein–Barr virus in productively infected B cells points to (innate) targets for immune evasion M Van Gent, AM Gram, IGJ Boer, RJ Geerdink, MFS Lindenbergh, ... Journal of General Virology 96 (4), 858-865, 2015 | 39 | 2015 |
ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease GQ Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ... Biorxiv, 2020 | 25 | 2020 |
The US3 kinase of herpes simplex virus phosphorylates the RNA sensor RIG-I to suppress innate immunity M van Gent, JJ Chiang, S Muppala, C Chiang, W Azab, L Kattenhorn, ... Journal of Virology 96 (4), e01510-21, 2022 | 24 | 2022 |
GTF3A mutations predispose to herpes simplex encephalitis by disrupting biogenesis of the host-derived RIG-I ligand RNA5SP141 L Naesens, S Muppala, D Acharya, J Nemegeer, D Bogaert, JH Lee, ... Science immunology 7 (77), eabq4531, 2022 | 23 | 2022 |
The herpesvirus accessory protein γ134.5 facilitates viral replication by disabling mitochondrial translocation of RIG-I X Liu, Y Ma, K Voss, M van Gent, YK Chan, MU Gack, M Gale Jr, B He PLoS pathogens 17 (3), e1009446, 2021 | 23 | 2021 |
ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity. Nat Microbiol 6: 467–478 G Liu, JH Lee, ZM Parker, D Acharya, JJ Chiang, M van Gent, W Riedl, ... | 23 | 2021 |
Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV M van Gent, A Reich, SE Velu, MU Gack PLoS Biology 19 (2), e3001097, 2021 | 13 | 2021 |
Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity AT Tromp, M Van Gent, JP Jansen, LM Scheepmaker, A Velthuizen, ... Toxins 12 (2), 106, 2020 | 11 | 2020 |