The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, A Revenko, ... Cancer research 73 (3), 1180-1189, 2013 | 1774 | 2013 |
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer D Hong, R Kurzrock, Y Kim, R Woessner, A Younes, J Nemunaitis, ... Science translational medicine 7 (314), 314ra185-314ra185, 2015 | 468 | 2015 |
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding AS Revenko, D Gao, JR Crosby, G Bhattacharjee, C Zhao, C May, ... Blood, The Journal of the American Society of Hematology 118 (19), 5302-5311, 2011 | 250 | 2011 |
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk H Zhang, EC Löwenberg, JR Crosby, AR MacLeod, C Zhao, D Gao, ... Blood, The Journal of the American Society of Hematology 116 (22), 4684-4692, 2010 | 231 | 2010 |
STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial MJ Reilley, P McCoon, C Cook, P Lyne, R Kurzrock, Y Kim, R Woessner, ... Journal for immunotherapy of cancer 6, 1-10, 2018 | 220 | 2018 |
Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS SJ Ross, AS Revenko, LL Hanson, R Ellston, A Staniszewska, N Whalley, ... Science translational medicine 9 (394), eaal5253, 2017 | 203 | 2017 |
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits JW Yau, P Liao, JC Fredenburgh, AR Stafford, AS Revenko, BP Monia, ... Blood, The Journal of the American Society of Hematology 123 (13), 2102-2107, 2014 | 189 | 2014 |
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb … EV Kalashnikova, AS Revenko, AT Gemo, NP Andrews, CG Tepper, ... Cancer research 70 (22), 9402-9412, 2010 | 183 | 2010 |
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERα, is required for coregulator occupancy and chromatin modification JX Zou, AS Revenko, LB Li, AT Gemo, HW Chen Proceedings of the National Academy of Sciences 104 (46), 18067-18072, 2007 | 180 | 2007 |
Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates JR Crosby, U Marzec, AS Revenko, C Zhao, D Gao, A Matafonov, ... Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1670-1678, 2013 | 166 | 2013 |
Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer JX Zou, L Guo, AS Revenko, CG Tepper, AT Gemo, HJ Kung, HW Chen Cancer research 69 (8), 3339-3346, 2009 | 166 | 2009 |
Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides … M Tanowitz, L Hettrick, A Revenko, GA Kinberger, TP Prakash, PP Seth Nucleic acids research 45 (21), 12388-12400, 2017 | 149 | 2017 |
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark AS Revenko, EV Kalashnikova, AT Gemo, JX Zou, HW Chen Molecular and cellular biology 30 (22), 5260-5272, 2010 | 138 | 2010 |
Colon cancer growth and dissemination relies upon thrombin, stromal PAR-1, and fibrinogen GN Adams, L Rosenfeldt, M Frederick, W Miller, D Waltz, K Kombrinck, ... Cancer research 75 (19), 4235-4243, 2015 | 132 | 2015 |
New developments in anticoagulants: past, present and future JI Weitz, J Harenberg Thrombosis and haemostasis 117 (07), 1283-1288, 2017 | 118 | 2017 |
Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines E Linnane, P Davey, P Zhang, S Puri, M Edbrooke, E Chiarparin, ... Nucleic acids research 47 (9), 4375-4392, 2019 | 106 | 2019 |
Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice ZL Chen, AS Revenko, P Singh, AR MacLeod, EH Norris, S Strickland Blood, The Journal of the American Society of Hematology 129 (18), 2547-2556, 2017 | 90 | 2017 |
Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity MC Louie, AS Revenko, JX Zou, J Yao, HW Chen Molecular and cellular biology 26 (10), 3810-3823, 2006 | 89 | 2006 |
Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides S Wang, N Allen, TA Vickers, AS Revenko, H Sun, X Liang, ST Crooke Nucleic acids research 46 (7), 3579-3594, 2018 | 82 | 2018 |
Modulation of tumor eIF4E by antisense inhibition: A phase I/II translational clinical trial of ISIS 183750—an antisense oligonucleotide against eIF4E—in combination with … AG Duffy, OV Makarova‐Rusher, SV Ulahannan, OE Rahma, S Fioravanti, ... International journal of cancer 139 (7), 1648-1657, 2016 | 80 | 2016 |