microRNAs: a newly described class of encoded molecules that play a role in health and disease K Felekkis, E Touvana, C Stefanou, C Deltas Hippokratia 14 (4), 236, 2010 | 544 | 2010 |
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter D Cai, A Iyer, KN Felekkis, RI Near, Z Luo, J Chernoff, C Albanese, ... Cancer research 63 (20), 6802-6808, 2003 | 103 | 2003 |
Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis S Tiwari, K Felekkis, EY Moon, A Flies, DH Sherr, A Lerner Blood 103 (7), 2661-2667, 2004 | 93 | 2004 |
Evidence for activation of the unfolded protein response in collagen IV nephropathies M Pieri, C Stefanou, A Zaravinos, K Erguler, K Stylianou, G Lapathitis, ... Journal of the American Society of Nephrology 25 (2), 260-275, 2014 | 92 | 2014 |
Challenges in using circulating micro-RNAs as biomarkers for cardiovascular diseases K Felekkis, C Papaneophytou International Journal of Molecular Sciences 21 (2), 561, 2020 | 81 | 2020 |
AND-34 Activates Phosphatidylinositol 3-Kinase and Induces Anti-Estrogen Resistance in a SH2 and GDP Exchange Factor–Like Domain-Dependent Manner KN Felekkis, RP Narsimhan, R Near, AF Castro, Y Zheng, LA Quilliam, ... Molecular Cancer Research 3 (1), 32-41, 2005 | 75 | 2005 |
The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42 D Cai, KN Felekkis, RI Near, GM O’Neill, JM Van Seventer, EA Golemis, ... The Journal of Immunology 170 (2), 969-978, 2003 | 72 | 2003 |
A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy G Papagregoriou, K Erguler, H Dweep, K Voskarides, P Koupepidou, ... Plos one 7 (2), e31021, 2012 | 55 | 2012 |
Increased number of microRNA target sites in genes encoded in CNV regions. Evidence for an evolutionary genomic interaction K Felekkis, K Voskarides, H Dweep, C Sticht, N Gretz, C Deltas Molecular biology and evolution 28 (9), 2421-2424, 2011 | 34 | 2011 |
A functional variant in NEPH3 gene confers high risk of renal failure in primary hematuric glomerulopathies. Evidence for predisposition to microalbuminuria in the … K Voskarides, C Stefanou, M Pieri, P Demosthenous, K Felekkis, M Arsali, ... PLoS One 12 (3), e0174274, 2017 | 28 | 2017 |
Catalyzing transcriptomics research in cardiovascular disease: the CardioRNA COST Action CA17129 CPC Gomes, B Ágg, A Andova, S Arslan, A Baker, M Barteková, D Beis, ... Non-coding RNA 5 (2), 31, 2019 | 25 | 2019 |
Survival of vaccine-induced human milk SARS-CoV-2 IgG, IgA and SIgA immunoglobulins across simulated human infant gastrointestinal digestion M Pieri, MA Maniori, L Shahabian, E Kanaan, I Paphiti-Demetriou, S Pipis, ... Nutrients 14 (16), 3368, 2022 | 24 | 2022 |
Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57 … KN Felekkis, P Koupepidou, E Kastanos, R Witzgall, CX Bai, L Li, ... BMC nephrology 9, 1-13, 2008 | 22 | 2008 |
Associations between serum biomarkers of cartilage metabolism and serum hyaluronic acid, with risk factors, pain categories, and disease severity in knee osteoarthritis: a … C Papaneophytou, A Alabajos-Cea, E Viosca-Herrero, C Calvis, M Costa, ... BMC Musculoskeletal Disorders 23 (1), 195, 2022 | 18 | 2022 |
CNVs-microRNAs interactions demonstrate unique characteristics in the human genome. An interspecies in silico analysis H Dweep, GD Georgiou, N Gretz, C Deltas, K Voskarides, K Felekkis PLoS One 8 (12), e81204, 2013 | 18 | 2013 |
Detection of SARS-CoV-2–Specific Antibodies in Human Breast Milk and Their Neutralizing Capacity after COVID-19 Vaccination: A Systematic Review V Nicolaidou, R Georgiou, M Christofidou, K Felekkis, M Pieri, ... International Journal of Molecular Sciences 24 (3), 2957, 2023 | 16 | 2023 |
The circulating biomarkers league: combining miRNAs with cell-free DNAs and proteins K Felekkis, C Papaneophytou International Journal of Molecular Sciences 25 (6), 3403, 2024 | 13 | 2024 |
Cyst formation in the PKD2 (1-703) transgenic rat precedes deregulation of proliferation-related pathways P Koupepidou, KN Felekkis, B Kränzlin, C Sticht, N Gretz, C Deltas BMC nephrology 11, 1-15, 2010 | 13 | 2010 |
RNA intereference: a powerful laboratory tool and its therapeutic implications K Felekkis, C Deltas Hippokratia 10 (3), 112, 2006 | 13 | 2006 |
Exploring the feasibility of circulating miRNAs as diagnostic and prognostic biomarkers in osteoarthritis: challenges and opportunities K Felekkis, M Pieri, C Papaneophytou International Journal of Molecular Sciences 24 (17), 13144, 2023 | 12 | 2023 |