Mitochondrial heterogeneity J Aryaman, IG Johnston, NS Jones Frontiers in Genetics 9, 718, 2019 | 117 | 2019 |
High prevalence of focal and multi-focal somatic genetic variants in the human brain MJ Keogh, W Wei, J Aryaman, L Walker, J van den Ameele, J Coxhead, ... Nature communications 9 (1), 4257, 2018 | 69 | 2018 |
Mitochondrial Network State Scales mtDNA Genetic Dynamics J Aryaman, C Bowles, NS Jones, IG Johnston Genetics 212 (4), 1429-1443, 2019 | 42 | 2019 |
Mitochondrial DNA heteroplasmy is modulated during oocyte development propagating mutation transmission H Zhang, M Esposito, MG Pezet, J Aryaman, W Wei, F Klimm, ... Science Advances 7 (50), eabi5657, 2021 | 31 | 2021 |
Frequency and signature of somatic variants in 1461 human brain exomes W Wei, MJ Keogh, J Aryaman, Z Golder, PJ Kullar, I Wilson, K Talbot, ... Genetics in Medicine 21 (4), 904-912, 2019 | 30 | 2019 |
Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains MJ Keogh, W Wei, J Aryaman, I Wilson, K Talbot, MR Turner, ... Journal of Neurology, Neurosurgery & Psychiatry 89 (8), 813-816, 2018 | 29 | 2018 |
Mitochondrial heterogeneity, metabolic scaling and cell death J Aryaman, H Hoitzing, JP Burgstaller, IG Johnston, NS Jones Bioessays 39 (7), 1700001, 2017 | 28 | 2017 |
Mitochondrial DNA density homeostasis accounts for a threshold effect in a cybrid model of a human mitochondrial disease J Aryaman, IG Johnston, NS Jones Biochemical Journal 474 (23), 4019-4034, 2017 | 16 | 2017 |
Stochastic survival of the densest and mitochondrial DNA clonal expansion in aging F Insalata, H Hoitzing, J Aryaman, NS Jones Proceedings of the National Academy of Sciences 119 (49), e2122073119, 2022 | 9 | 2022 |
Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro MG Pezet, A Gomez-Duran, F Klimm, J Aryaman, S Burr, W Wei, M Saitou, ... Communications Biology 4 (1), 584, 2021 | 9 | 2021 |
Stochastic survival of the densest and mitochondrial DNA clonal expansion in ageing F Insalata, H Hoitzing, J Aryaman, NS Jones bioRxiv, 2020.09. 01.277137, 2020 | 1 | 2020 |
Cryptic mitochondrial ageing coincides with mid-late life and is pathophysiologically informative in single cells across tissues and species AP Green, F Klimm, AS Marshall, R Leetmaa, J Aryaman, A Gómez-Durán, ... bioRxiv, 2023.07. 04.547509, 2023 | | 2023 |
Understanding the mechanism underpinning the transmission of mtDNA mutations M Pezet, A Gomez-Duran, J Aryaman, NS Jones, PF Chinnery Neuromuscular Disorders 28, S35, 2018 | | 2018 |
Stochastic modelling and inference for mitochondria in health and disease J Aryaman Imperial College London, 2018 | | 2018 |