| Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... Nature communications 11 (1), 5370, 2020 | 271 | 2020 |
| Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ... Molecular neurodegeneration 16, 1-11, 2021 | 111 | 2021 |
| Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 105 | 2022 |
| Engineering an inhibitor-resistant human CSF1R variant for microglia replacement JP Chadarevian, SI Lombroso, GC Peet, J Hasselmann, C Tu, DE Marzan, ... Journal of Experimental Medicine 220 (3), e20220857, 2022 | 48 | 2022 |
| TREM2 regulates purinergic receptor-mediated calcium signaling and motility in human iPSC-derived microglia A Jairaman, A McQuade, A Granzotto, YJ Kang, JP Chadarevian, ... Elife 11, e73021, 2022 | 48 | 2022 |
| The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ... Alzheimer's & Dementia 18 (10), 1765-1778, 2022 | 38 | 2022 |
| A chemical-genetic approach reveals the distinct roles of GSK3α and GSK3β in regulating embryonic stem cell fate X Chen, R Wang, X Liu, Y Wu, T Zhou, Y Yang, A Perez, YC Chen, L Hu, ... Developmental cell 43 (5), 563-576. e4, 2017 | 36 | 2017 |
| Cytoplasmic and nuclear TAZ exert distinct functions in regulating primed pluripotency X Zhou, JP Chadarevian, B Ruiz, QL Ying Stem cell reports 9 (3), 732-741, 2017 | 30 | 2017 |
| The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C JV Pluvinage, J Sun, C Claes, RA Flynn, MS Haney, T Iram, X Meng, ... Science translational medicine 13 (622), eabg2919, 2021 | 29 | 2021 |
| Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... nature communications 14, 1194, 2023 | 27 | 2023 |
| Microglia protect against age-associated brain pathologies DAD Munro, N Bestard-Cuche, C McQuaid, A Chagnot, SK Shabestari, ... Neuron 112 (16), 2732-2748. e8, 2024 | 23 | 2024 |
| Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy JP Chadarevian, J Hasselmann, A Lahian, JK Capocchi, A Escobar, ... Neuron 112 (16), 2686-2707. e8, 2024 | 20 | 2024 |
| A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: Therapeutic efficacy in PS19 mice A Hovakimyan, T Antonyan, SK Shabestari, O Svystun, G Chailyan, ... Scientific reports 9 (1), 15455, 2019 | 20 | 2019 |
| Controlled release of stem cell secretome attenuates inflammatory response against implanted biomaterials M Mohammadi, JC Luong, SM Rodriguez, R Cao, AE Wheeler, H Lau, ... Advanced healthcare materials 9 (12), 1901874, 2020 | 14 | 2020 |
| Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease N Rosenzweig, KL Kleemann, T Rust, M Carpenter, M Grucci, M Aronchik, ... Nature Medicine 30 (10), 2990-3003, 2024 | 12 | 2024 |
| Autologous transplantation of skin-derived precursor cells in a porcine model AL Thomas, JS Taylor, N Huynh, G Dubrovsky, JP Chadarevian, A Chen, ... Journal of Pediatric Surgery 55 (1), 194-200, 2020 | 6 | 2020 |
| Novel vaccine against pathological pyroglutamate-modified amyloid beta for prevention of Alzheimer’s disease K Zagorski, O King, A Hovakimyan, I Petrushina, T Antonyan, G Chailyan, ... International journal of molecular sciences 24 (12), 9797, 2023 | 5 | 2023 |
| PILRA regulates microglial neuroinflammation and lipid metabolism as a candidate therapeutic target for Alzheimer’s disease K Monroe, T Weerakkody, H Sabelström, D Tatarakis, J Suh, M Chin, ... | 4 | 2024 |
| CRISPR generation of CSF1R-G795A human microglia for robust microglia replacement in a chimeric mouse model JP Chadarevian, H Davtyan, SI Lombroso, FC Bennett, M Blurton-Jones STAR protocols 4 (3), 102490, 2023 | 4 | 2023 |
| ER and SOCE Ca2+ signals are not required for directed cell migration in human iPSC-derived microglia A Granzotto, A McQuade, JP Chadarevian, H Davtyan, SL Sensi, I Parker, ... Cell Calcium 123, 102923, 2024 | 2 | 2024 |