Mixed‐polarization phenotype of ascites‐associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse S Reinartz, T Schumann, F Finkernagel, A Wortmann, JM Jansen, ... International journal of cancer 134 (1), 32-42, 2014 | 285 | 2014 |
The Transcription Factor Rbf1 Is the Master Regulator for b-Mating Type Controlled Pathogenic Development in Ustilago maydis K Heimel, M Scherer, M Vranes, R Wahl, C Pothiratana, D Schuler, ... PLoS pathogens 6 (8), e1001035, 2010 | 129 | 2010 |
Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C AM Steitz, A Steffes, F Finkernagel, A Unger, L Sommerfeld, JM Jansen, ... Cell death & disease 11 (4), 249, 2020 | 120 | 2020 |
MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1. 6 B Stielow, F Finkernagel, T Stiewe, A Nist, G Suske PLoS genetics 14 (1), e1007193, 2018 | 118 | 2018 |
A transcriptome-based global map of signaling pathways in the ovarian cancer microenvironment associated with clinical outcome S Reinartz, F Finkernagel, T Adhikary, V Rohnalter, T Schumann, ... Genome biology 17, 1-22, 2016 | 110 | 2016 |
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) T Adhikary, K Kaddatz, F Finkernagel, A Schönbauer, W Meissner, ... PloS one 6 (1), e16344, 2011 | 109 | 2011 |
The transcriptional PPARβ/δ network in human macrophages defines a unique agonist-induced activation state T Adhikary, A Wortmann, T Schumann, F Finkernagel, S Lieber, K Roth, ... Nucleic acids research 43 (10), 5033-5051, 2015 | 101 | 2015 |
Inverse PPARβ/δ agonists suppress oncogenic signaling to the ANGPTL4 gene and inhibit cancer cell invasion T Adhikary, DT Brandt, K Kaddatz, J Stockert, S Naruhn, W Meissner, ... Oncogene 32 (44), 5241-5252, 2013 | 101 | 2013 |
Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML (vol 32, pg 829, 2017) C Schutz, S Inselmann, S Saussele, CT Dietz, MC Muller, E Eigendorff, ... LEUKEMIA 32 (4), 1053-1053, 2018 | 100* | 2018 |
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization F Finkernagel, S Reinartz, S Lieber, T Adhikary, A Wortmann, N Hoffmann, ... Oncotarget 7 (46), 75339, 2016 | 100 | 2016 |
Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment T Schumann, T Adhikary, A Wortmann, F Finkernagel, S Lieber, ... Oncotarget 6 (15), 13416, 2015 | 100 | 2015 |
Characterization of the p53 cistrome–DNA binding cooperativity dissects p53's tumor suppressor functions K Schlereth, C Heyl, AM Krampitz, M Mernberger, F Finkernagel, ... PLoS genetics 9 (8), e1003726, 2013 | 99 | 2013 |
A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory … V Rohnalter, K Roth, F Finkernagel, T Adhikary, J Obert, K Dorzweiler, ... Oncotarget 6 (37), 40005, 2015 | 96 | 2015 |
Transcriptional profiling identifies functional interactions of TGFβ and PPARβ/δ signaling: synergistic induction of ANGPTL4 transcription K Kaddatz, T Adhikary, F Finkernagel, W Meissner, S MÜller-BrÜsselbach, ... Journal of Biological Chemistry 285 (38), 29469-29479, 2010 | 93 | 2010 |
Prognosis of ovarian cancer is associated with effector memory CD8+ T cell accumulation in ascites, CXCL9 levels and activation-triggered signal transduction in T … S Lieber, S Reinartz, H Raifer, F Finkernagel, T Dreyer, H Bronger, ... Oncoimmunology 7 (5), e1424672, 2018 | 86 | 2018 |
Rhythmic U2af26 alternative splicing controls PERIOD1 stability and the circadian clock in mice M Preußner, I Wilhelmi, AS Schultz, F Finkernagel, M Michel, T Möröy, ... Molecular cell 54 (4), 651-662, 2014 | 82 | 2014 |
Proteotranscriptomics reveal signaling networks in the ovarian cancer microenvironment T Worzfeld, F Finkernagel, S Reinartz, A Konzer, T Adhikary, A Nist, ... Molecular & Cellular Proteomics 17 (2), 270-289, 2018 | 68 | 2018 |
Multi-platform affinity proteomics identify proteins linked to metastasis and immune suppression in ovarian cancer plasma J Graumann, F Finkernagel, S Reinartz, T Stief, D Brödje, H Renz, ... Frontiers in oncology 9, 1150, 2019 | 67 | 2019 |
Cell type‐selective pathways and clinical associations of lysophosphatidic acid biosynthesis and signaling in the ovarian cancer microenvironment S Reinartz, S Lieber, J Pesek, DT Brandt, A Asafova, F Finkernagel, ... Molecular oncology 13 (2), 185-201, 2019 | 67 | 2019 |
Zinc finger independent genome-wide binding of Sp2 potentiates recruitment of histone-fold protein Nf-y distinguishing it from Sp1 and Sp3 S Völkel, B Stielow, F Finkernagel, T Stiewe, A Nist, G Suske PLoS genetics 11 (3), e1005102, 2015 | 65 | 2015 |