עקוב אחר
Siddharth Matikonda, Ph.D.
Siddharth Matikonda, Ph.D.
Senior Scientist, Biologics Engineering-Targeted Delivery, AstraZeneca
כתובת אימייל מאומתת בדומיין astrazeneca.com - דף הבית
כותרת
צוטט על ידי
צוטט על ידי
שנה
Bioorthogonal prodrug activation driven by a strain-promoted 1, 3-dipolar cycloaddition
SS Matikonda, DL Orsi, V Staudacher, IA Jenkins, F Fiedler, J Chen, ...
Chemical Science 6 (2), 1212-1218, 2015
1552015
Impact of cyanine conformational restraint in the near-infrared range
SS Matikonda, G Hammersley, N Kumari, L Grabenhorst, V Glembockyte, ...
The Journal of organic chemistry 85 (9), 5907-5915, 2020
772020
Photoblueing of organic dyes can cause artifacts in super-resolution microscopy
DA Helmerich, G Beliu, SS Matikonda, MJ Schnermann, M Sauer
Nature Methods 18 (3), 253-257, 2021
752021
Defining the basis of cyanine phototruncation enables a new approach to single-molecule localization microscopy
SS Matikonda, DA Helmerich, M Meub, G Beliu, P Kollmannsberger, ...
ACS Central Science 7 (7), 1144-1155, 2021
732021
Preparation of fluoroalkenes via the shapiro reaction: direct access to fluorinated peptidomimetics
MH Yang, SS Matikonda, RA Altman
Organic Letters 15 (15), 3894-3897, 2013
692013
Identification and structure–activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors
R Alokam, VU Jeankumar, JP Sridevi, SS Matikonda, S Peddi, M Alvala, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 29 (4), 547-554, 2014
512014
Hypoxia responsive drug delivery systems in tumor therapy
H Alimoradi, S S Matikonda, A B Gamble, G I Giles, K Greish
Current pharmaceutical design 22 (19), 2808-2820, 2016
482016
Core remodeling leads to long wavelength fluoro-coumarins
SS Matikonda, J Ivanic, M Gomez, G Hammersley, MJ Schnermann
Chemical Science 11 (28), 7302-7307, 2020
472020
Mechanistic Evaluation of Bioorthogonal Decaging with trans-Cyclooctene: The Effect of Fluorine Substituents on Aryl Azide Reactivity and Decaging from the 1,2,3 …
SS Matikonda, JM Fairhall, F Fiedler, S Sanhajariya, RAJ Tucker, S Hook, ...
Bioconjugate chemistry 29 (2), 324-334, 2018
452018
Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors
VU Jeankumar, R Alokam, JP Sridevi, P Suryadevara, SS Matikonda, ...
Chemical biology & drug design 83 (4), 498-506, 2014
402014
Targetable Conformationally Restricted Cyanines Enable Photon‐Count‐Limited Applications
P Eiring, R McLaughlin, SS Matikonda, Z Han, L Grabenhorst, ...
Angewandte Chemie International Edition 60 (51), 26685-26693, 2021
302021
Cyanine phototruncation enables spatiotemporal cell labeling
H Fukushima, SS Matikonda, SM Usama, A Furusawa, T Kato, ...
Journal of the American Chemical Society 144 (25), 11075-11080, 2022
262022
Ketone Incorporation Extends the Emission Properties of the Xanthene Scaffold Beyond 1000 nm
HC Daly, SS Matikonda, H Steffens, B Ruehle, U Resch‐Genger, J Ivanic, ...
Photochemistry and Photobiology, 2021
262021
Structure-Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold
S Matikonda, R Mclaughlin, P Shrestha, C Lipshultz, M Schnermann
Bioconjugate Chemistry, 2022
232022
Stability, kinetic, and mechanistic investigation of 1, 8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively …
SS Matikonda, JM Fairhall, JDA Tyndall, S Hook, AB Gamble
Organic letters 19 (3), 528-531, 2017
142017
Synthesis and Biological Evaluation of Aurachin D Analogues as Inhibitors of Mycobacterium tuberculosis Cytochrome bd Oxidase
A Lawer, C Tyler, K Hards, LM Keighley, CY Cheung, F Kierek, S Su, ...
ACS medicinal chemistry letters 13 (10), 1663-1669, 2022
82022
GABA derivatives for the treatment of epilepsy and neuropathic pain: a synthetic integration of GABA in 1, 2, 4–Triazolo–2H–one nucleus
P Yogeeswari, SK Patel, IV Reddy, A Semwal, M Sharma, M Gangadhar, ...
Biomedicine & Aging Pathology 2 (2), 31-40, 2012
72012
Phototruncation cell tracking with near-infrared photoimmunotherapy using heptamethine cyanine dye to visualise migratory dynamics of immune cells
H Fukushima, A Furusawa, S Takao, SS Matikonda, M Kano, S Okuyama, ...
EBioMedicine 102, 2024
62024
Conformationally restrained pentamethine cyanines and use in reductive single molecule localization microscopy
SS Matikonda, R McLaughlin, M Sauer, MJ Schnermann
Methods in Enzymology, 2020
52020
Bluer Phototruncation: Retro-Diels–Alder of Heptamethine Cyanine to Trimethine Cyanine through an Allene Hydroperoxide Intermediate
L Lapoot, C Wang, SS Matikonda, MJ Schnermann, A Greer
The Journal of Organic Chemistry 88 (24), 17430-17437, 2023
32023
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מאמרים 1–20