Comparison of [11C]-(R)-PK 11195 and [11C] PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging … WC Kreisl, M Fujita, Y Fujimura, N Kimura, KJ Jenko, P Kannan, J Hong, ... Neuroimage 49 (4), 2924-2932, 2010 | 308 | 2010 |
Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications P Kannan, C John, SS Zoghbi, C Halldin, MM Gottesman, RB Innis, ... Clinical Pharmacology & Therapeutics 86 (4), 368-377, 2009 | 227 | 2009 |
The “specific” P-glycoprotein inhibitor tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2) P Kannan, S Telu, S Shukla, SV Ambudkar, VW Pike, C Halldin, ... ACS Chemical Neuroscience 2 (2), 82-89, 2010 | 201 | 2010 |
Tariquidar is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein LD Weidner, KL Fung, P Kannan, JK Moen, JS Kumar, J Mulder, RB Innis, ... Drug Metabolism and Disposition 44 (2), 275-282, 2016 | 86 | 2016 |
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, B Gilmour, ... Journal of natural products 69 (1), 107-112, 2006 | 81 | 2006 |
Synthesis of salvinorin A analogues as opioid receptor probes K Tidgewell, WW Harding, A Lozama, H Cobb, K Shah, P Kannan, ... Journal of natural products 69 (6), 914-918, 2006 | 73 | 2006 |
Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl) ethynyl) benzonitrile ([18F] SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 … HU Shetty, SS Zoghbi, FG Siméon, JS Liow, AK Brown, P Kannan, ... Journal of Pharmacology and Experimental Therapeutics 327 (3), 727-735, 2008 | 69 | 2008 |
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: Selective modification of the furan ring WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, CM Dersch, ... Bioorganic & medicinal chemistry letters 16 (12), 3170-3174, 2006 | 68 | 2006 |
The Role of Oxygen in Avascular Tumor Growth DR Grimes, P Kannan, A McIntyre, A Kavanagh, A Siddiky, S Wigfield, ... PLoS ONE 11 (4), e0153692, 2016 | 66 | 2016 |
Estimating oxygen distribution from vasculature in three-dimensional tumour tissue DR Grimes, P Kannan, DR Warren, B Markelc, R Bates, R Muschel, ... Journal of The Royal Society Interface 13 (116), 20160070, 2016 | 65 | 2016 |
The expression of inflammatory markers and their potential influence on efflux transporters in drug‐resistant mesial temporal lobe epilepsy tissue LD Weidner, P Kannan, N Mitsios, SJ Kang, MD Hall, WH Theodore, ... Epilepsia 59 (8), 1507-1517, 2018 | 60 | 2018 |
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET P Kannan, KR Brimacombe, WC Kreisl, JS Liow, SS Zoghbi, S Telu, ... Proceedings of the National Academy of Sciences 108 (6), 2593-2598, 2011 | 59 | 2011 |
Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia CJ Kelly, K Hussien, E Fokas, P Kannan, RJ Shipley, TM Ashton, ... Radiotherapy and Oncology, 2014 | 57 | 2014 |
Bayesian calibration, validation and uncertainty quantification for predictive modelling of tumour growth: a tutorial J Collis, AJ Connor, M Paczkowski, P Kannan, J Pitt-Francis, HM Byrne, ... Bulletin of mathematical biology 79 (4), 939-974, 2017 | 56 | 2017 |
N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier P Kannan, KR Brimacombe, SS Zoghbi, JS Liow, C Morse, AK Taku, ... Drug Metabolism and Disposition 38 (6), 917-922, 2010 | 53 | 2010 |
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin AS Goldsborough, MD Handley, AE Dulcey, KM Pluchino, P Kannan, ... Journal of medicinal chemistry 54 (14), 4987-4997, 2011 | 50 | 2011 |
maskSLIC: Regional Superpixel Generation with Application to Local Pathology Characterisation in Medical Images B Irving, IA Popescu, R Bates, PD Allen, AL Gomes, P Kannan, ... | 42* | |
Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer M Paczkowski, WW Kretzschmar, B Markelc, SK Liu, LA Kunz-Schughart, ... Communications Biology 4 (6), 1-13, 2021 | 38 | 2021 |
Factors that limit PET imaging of P-glycoprotein density at the blood-brain barrier P Kannan, VW Pike, C Halldin, O Langer, MM Gottesman, RB Innis, ... Molecular pharmaceutics, 2013 | 26 | 2013 |
An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter P Kannan, M Schain, WW Kretzschmar, L Weidner, N Mitsios, B Gulyás, ... Journal of Cerebral Blood Flow & Metabolism 37 (6), 2062-2075, 2017 | 24 | 2017 |