Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate DAM van Dartel, JLA Pennings, PJM Hendriksen, FJ van Schooten, ... Reproductive toxicology 27 (2), 93-102, 2009 | 90 | 2009 |
Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes claudin 7 LM JanssenDuijghuijsen, S Grefte, VCJ De Boer, L Zeper, ... Frontiers in physiology 8, 794, 2017 | 78 | 2017 |
Evaluation of developmental toxicant identification using gene expression profiling in embryonic stem cell differentiation cultures DAM van Dartel, JLA Pennings, LJJ de la Fonteyne, KJJ Brauers, ... Toxicological Sciences 119 (1), 126-134, 2011 | 77 | 2011 |
Transcriptomics-based identification of developmental toxicants through their interference with cardiomyocyte differentiation of embryonic stem cells DAM van Dartel, JLA Pennings, FJ van Schooten, AH Piersma Toxicology and applied pharmacology 243 (3), 420-428, 2010 | 76 | 2010 |
An abbreviated protocol for multilineage neural differentiation of murine embryonic stem cells and its perturbation by methyl mercury PT Theunissen, SHW Schulpen, DAM Van Dartel, SAB Hermsen, ... Reproductive toxicology 29 (4), 383-392, 2010 | 74 | 2010 |
Monitoring developmental toxicity in the embryonic stem cell test using differential gene expression of differentiation-related genes DAM van Dartel, JLA Pennings, LJJ de la Fonteyne, MH van Herwijnen, ... Toxicological sciences 116 (1), 130-139, 2010 | 74 | 2010 |
Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet W Shi, MA Hegeman, DAM van Dartel, J Tang, M Suarez, H Swarts, ... Molecular nutrition & food research 61 (8), 1600878, 2017 | 65 | 2017 |
Proteome profiling of mouse embryonic stem cells to define markers for cell differentiation and embryotoxicity AM Osman, DAM van Dartel, E Zwart, M Blokland, JLA Pennings, ... Reproductive Toxicology 30 (2), 322-332, 2010 | 62 | 2010 |
The embryonic stem cell test combined with toxicogenomics as an alternative testing model for the assessment of developmental toxicity DAM van Dartel, AH Piersma Reproductive toxicology 32 (2), 235-244, 2011 | 61 | 2011 |
Complementary detection of embryotoxic properties of substances in the neural and cardiac embryonic stem cell tests PT Theunissen, JLA Pennings, DAM van Dartel, JF Robinson, ... toxicological sciences 132 (1), 118-130, 2013 | 56 | 2013 |
Discriminating classes of developmental toxicants using gene expression profiling in the embryonic stem cell test DAM van Dartel, JLA Pennings, JF Robinson, JCS Kleinjans, AH Piersma Toxicology Letters 201 (2), 143-151, 2011 | 53 | 2011 |
Concentration-dependent gene expression responses to flusilazole in embryonic stem cell differentiation cultures DAM van Dartel, JLA Pennings, LJJ de la Fonteyne, KJJ Brauers, ... Toxicology and applied pharmacology 251 (2), 110-118, 2011 | 53 | 2011 |
Gene set assembly for quantitative prediction of developmental toxicity in the embryonic stem cell test JLA Pennings, DAM van Dartel, JF Robinson, TE Pronk, AH Piersma Toxicology 284 (1-3), 63-71, 2011 | 47 | 2011 |
The effect of endurance exercise on intestinal integrity in well‐trained healthy men LM JanssenDuijghuijsen, M Mensink, K Lenaerts, E Fiedorowicz, ... Physiological Reports 4 (20), e12994, 2016 | 46 | 2016 |
Disentangling cellular proliferation and differentiation in the embryonic stem cell test, and its impact on the experimental protocol DAM van Dartel, NJL Zeijen, LJJ de la Fonteyne, FJ van Schooten, ... Reproductive Toxicology 28 (2), 254-261, 2009 | 43 | 2009 |
Comparison of MeHg-induced toxicogenomic responses across in vivo and in vitro models used in developmental toxicology JF Robinson, PT Theunissen, DAM van Dartel, JL Pennings, ... Reproductive toxicology 32 (2), 180-188, 2011 | 39 | 2011 |
Dose response analysis of monophthalates in the murine embryonic stem cell test assessed by cardiomyocyte differentiation and gene expression SHW Schulpen, JF Robinson, JLA Pennings, DAM van Dartel, ... Reproductive Toxicology 35, 81-88, 2013 | 30 | 2013 |
Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice M van Dijk, FJ Dijk, A Bunschoten, DAM van Dartel, K van Norren, ... Oncotarget 7 (14), 17338, 2016 | 29 | 2016 |
Next-generation text-mining mediated generation of chemical response-specific gene sets for interpretation of gene expression data KM Hettne, A Boorsma, DAM van Dartel, JJ Goeman, E de Jong, ... BMC Medical Genomics 6, 1-17, 2013 | 21 | 2013 |
Effects of flavonoid mixtures on the transport of 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) through Caco-2 monolayers: An in vitro and kinetic modeling approach … ME Schutte, MG Boersma, DAM Verhallen, JP Groten, IMCM Rietjens Food and Chemical Toxicology 46 (2), 557-566, 2008 | 17 | 2008 |