Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development F Baenke, B Peck, H Miess, A Schulze Disease models & mechanisms 6 (6), 1353-1363, 2013 | 879 | 2013 |
Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ... Cancer cell 27 (1), 57-71, 2015 | 800 | 2015 |
Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation K Bensaad, E Favaro, CA Lewis, B Peck, S Lord, JM Collins, KE Pinnick, ... Cell reports 9 (1), 349-365, 2014 | 681 | 2014 |
SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2 B Peck, CY Chen, KK Ho, P Di Fruscia, SS Myatt, RC Coombes, ... Molecular cancer therapeutics 9 (4), 844-855, 2010 | 521 | 2010 |
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma H Miess, B Dankworth, AM Gouw, M Rosenfeldt, W Schmitz, M Jiang, ... Oncogene 37 (40), 5435-5450, 2018 | 319 | 2018 |
FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression EC Ferber, B Peck, O Delpuech, GP Bell, P East, A Schulze Cell Death & Differentiation 19 (6), 968-979, 2012 | 317 | 2012 |
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth B Griffiths, CA Lewis, K Bensaad, S Ros, Q Zhang, EC Ferber, S Konisti, ... Cancer & metabolism 1, 1-21, 2013 | 284 | 2013 |
SREBP maintains lipid biosynthesis and viability of cancer cells under lipid-and oxygen-deprived conditions and defines a gene signature associated with poor survival in … CA Lewis, C Brault, B Peck, K Bensaad, B Griffiths, R Mitter, ... Oncogene 34 (40), 5128-5140, 2015 | 256 | 2015 |
FOXM1 confers acquired cisplatin resistance in breast cancer cells JMM Kwok, B Peck, LJ Monteiro, HDC Schwenen, J Millour, RC Coombes, ... Molecular cancer research 8 (1), 24-34, 2010 | 248 | 2010 |
Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments B Peck, ZT Schug, Q Zhang, B Dankworth, DT Jones, E Smethurst, ... Cancer & metabolism 4, 1-18, 2016 | 244 | 2016 |
Lipid desaturation–the next step in targeting lipogenesis in cancer? B Peck, A Schulze The FEBS journal 283 (15), 2767-2778, 2016 | 197 | 2016 |
Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer UB McGovern, RE Francis, B Peck, SK Guest, J Wang, SS Myatt, J Krol, ... Molecular cancer therapeutics 8 (3), 582-591, 2009 | 154 | 2009 |
FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer RE Francis, SS Myatt, J Krol, J Hartman, B Peck, UB McGovern, J Wang, ... International journal of oncology 35 (1), 57-68, 2009 | 153 | 2009 |
Lipid metabolism at the nexus of diet and tumor microenvironment B Peck, A Schulze Trends in cancer 5 (11), 693-703, 2019 | 116 | 2019 |
Antagonism between FOXO and MYC regulates cellular powerhouse B Peck, EC Ferber, A Schulze Frontiers in oncology 3, 96, 2013 | 91 | 2013 |
Three‐dimensional modelling identifies novel genetic dependencies associated with breast cancer progression in the isogenic MCF10 model SL Maguire, B Peck, PT Wai, J Campbell, H Barker, A Gulati, F Daley, ... The Journal of Pathology 240 (3), 315-328, 2016 | 46 | 2016 |
Cholesteryl esters: fueling the fury of prostate cancer B Peck, A Schulze Cell metabolism 19 (3), 350-352, 2014 | 36 | 2014 |
Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence Q Heydt, C Xintaropoulou, A Clear, M Austin, I Pislariu, F Miraki-Moud, ... Nature communications 12 (1), 5507, 2021 | 27 | 2021 |
3D growth of cancer cells elicits sensitivity to kinase inhibitors but not lipid metabolism modifiers DT Jones, A Valli, S Haider, Q Zhang, EA Smethurst, ZT Schug, B Peck, ... Molecular cancer therapeutics 18 (2), 376-388, 2019 | 25 | 2019 |
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response P Bland, H Saville, PT Wai, L Curnow, G Muirhead, J Nieminuszczy, ... Nature Genetics 55 (8), 1311-1323, 2023 | 22 | 2023 |