Accelerating adverse outcome pathway development using publicly available data sources NO Oki, MD Nelms, SM Bell, HM Mortensen, SW Edwards Current environmental health reports 3, 53-63, 2016 | 65 | 2016 |
Differentiating pathway-specific from nonspecific effects in high-throughput toxicity data: A foundation for prioritizing adverse outcome pathway development KA Fay, DL Villeneuve, J Swintek, SW Edwards, MD Nelms, BR Blackwell, ... Toxicological Sciences 163 (2), 500-515, 2018 | 55 | 2018 |
Development of an in Silico Profiler for Mitochondrial Toxicity MD Nelms, CL Mellor, MTD Cronin, JC Madden, SJ Enoch Chemical Research in Toxicology 28 (10), 1891-1902, 2015 | 55 | 2015 |
Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes MD Nelms, G Ates, JC Madden, M Vinken, MTD Cronin, V Rogiers, ... Archives of Toxicology 89, 733-741, 2015 | 35 | 2015 |
Identification of novel activators of the metal responsive transcription factor (MTF-1) using a gene expression biomarker in a microarray compendium AC Jackson, J Liu, B Vallanat, C Jones, MD Nelms, G Patlewicz, ... Metallomics 12 (9), 1400-1415, 2020 | 24 | 2020 |
Evaluating potential refinements to existing Threshold of Toxicological Concern (TTC) values for environmentally-relevant compounds MD Nelms, P Pradeep, G Patlewicz Regulatory Toxicology and Pharmacology 109, 104505, 2019 | 20 | 2019 |
Methods for assigning confidence to toxicity data with multiple values—Identifying experimental outliers FP Steinmetz, SJ Enoch, JC Madden, MD Nelms, N Rodriguez-Sanchez, ... Science of The Total Environment 482, 358-365, 2014 | 20 | 2014 |
Experimental verification, and domain definition, of structural alerts for protein binding: epoxides, lactones, nitroso, nitros, aldehydes and ketones MD Nelms, MTD Cronin, TW Schultz, SJ Enoch SAR and QSAR in Environmental Research 24 (9), 695-709, 2013 | 20 | 2013 |
COSMOS next generation–A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals C Yang, MTD Cronin, KB Arvidson, B Bienfait, SJ Enoch, B Heldreth, ... Computational Toxicology 19, 100175, 2021 | 18 | 2021 |
Derivation of new threshold of toxicological concern values for exposure via inhalation for environmentally-relevant chemicals MD Nelms, G Patlewicz Frontiers in toxicology 2, 580347, 2020 | 16 | 2020 |
An evaluation of the performance of selected (Q) SARs/expert systems for predicting acute oral toxicity MD Nelms, AL Karmaus, G Patlewicz Computational Toxicology 16, 100135, 2020 | 15 | 2020 |
Editor’s highlight: Negative predictors of carcinogenicity for environmental chemicals T Hill III, MD Nelms, SW Edwards, M Martin, R Judson, JC Corton, ... Toxicological Sciences 155 (1), 157-169, 2017 | 15 | 2017 |
A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions MD Nelms, CL Mellor, SJ Enoch, RS Judson, G Patlewicz, AM Richard, ... Computational Toxicology 8, 1-12, 2018 | 14 | 2018 |
Adverse outcome pathways to support the assessment of chemical mixtures MD Nelms, JE Simmons, SW Edwards Chemical Mixtures and Combined Chemical and Nonchemical Stressors: Exposure …, 2018 | 13 | 2018 |
In silico guidance for in vitro androgen and glucocorticoid receptor ToxCast assays TEH Allen, MD Nelms, SW Edwards, JM Goodman, S Gutsell, PJ Russell Environmental Science & Technology 54 (12), 7461-7470, 2020 | 9 | 2020 |
Mapping Mechanistic Pathways of Acute Oral Systemic Toxicity Using Chemical Structure and Bioactivity Measurements SW Edwards, M Nelms, VK Hench, J Ponder, K Sullivan Frontiers in Toxicology 4, 824094, 2022 | 6 | 2022 |
A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: a case study with dinitroaniline pesticides JA Leonard, M Nelms, E Craig, M Perron, H Pope-Varsalona, ... Regulatory Toxicology and Pharmacology 107, 104419, 2019 | 6 | 2019 |
Linking complex disease and exposure data—insights from an environmental and occupational health study C Ives, H Pan, SW Edwards, M Nelms, H Covert, MY Lichtveld, ... Journal of exposure science & environmental epidemiology 33 (1), 12-16, 2023 | 5 | 2023 |
Structure–activity modeling of mitochondrial dysfunction S Enoch, C Mellor, M Nelms Mitochondrial dysfunction caused by drugs and environmental toxicants, 25-34, 2018 | 5 | 2018 |
Development of new COSMOS oRepeatDose and non-cancer Threshold of Toxicological Concern (TTC) databases to support alternative testing methods for cosmetics related chemicals C Yang, M Ambrosio, K Arvidson, S Barlow, A Boobis, M Checheva, ... Toxicology letters 221, S80-S80, 2013 | 5 | 2013 |