עקוב אחר
Mark D Nelms
Mark D Nelms
כתובת אימייל מאומתת בדומיין rti.org
כותרת
צוטט על ידי
צוטט על ידי
שנה
Accelerating adverse outcome pathway development using publicly available data sources
NO Oki, MD Nelms, SM Bell, HM Mortensen, SW Edwards
Current environmental health reports 3, 53-63, 2016
652016
Differentiating pathway-specific from nonspecific effects in high-throughput toxicity data: A foundation for prioritizing adverse outcome pathway development
KA Fay, DL Villeneuve, J Swintek, SW Edwards, MD Nelms, BR Blackwell, ...
Toxicological Sciences 163 (2), 500-515, 2018
552018
Development of an in Silico Profiler for Mitochondrial Toxicity
MD Nelms, CL Mellor, MTD Cronin, JC Madden, SJ Enoch
Chemical Research in Toxicology 28 (10), 1891-1902, 2015
552015
Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes
MD Nelms, G Ates, JC Madden, M Vinken, MTD Cronin, V Rogiers, ...
Archives of Toxicology 89, 733-741, 2015
352015
Identification of novel activators of the metal responsive transcription factor (MTF-1) using a gene expression biomarker in a microarray compendium
AC Jackson, J Liu, B Vallanat, C Jones, MD Nelms, G Patlewicz, ...
Metallomics 12 (9), 1400-1415, 2020
242020
Evaluating potential refinements to existing Threshold of Toxicological Concern (TTC) values for environmentally-relevant compounds
MD Nelms, P Pradeep, G Patlewicz
Regulatory Toxicology and Pharmacology 109, 104505, 2019
202019
Methods for assigning confidence to toxicity data with multiple values—Identifying experimental outliers
FP Steinmetz, SJ Enoch, JC Madden, MD Nelms, N Rodriguez-Sanchez, ...
Science of The Total Environment 482, 358-365, 2014
202014
Experimental verification, and domain definition, of structural alerts for protein binding: epoxides, lactones, nitroso, nitros, aldehydes and ketones
MD Nelms, MTD Cronin, TW Schultz, SJ Enoch
SAR and QSAR in Environmental Research 24 (9), 695-709, 2013
202013
COSMOS next generation–A public knowledge base leveraging chemical and biological data to support the regulatory assessment of chemicals
C Yang, MTD Cronin, KB Arvidson, B Bienfait, SJ Enoch, B Heldreth, ...
Computational Toxicology 19, 100175, 2021
182021
Derivation of new threshold of toxicological concern values for exposure via inhalation for environmentally-relevant chemicals
MD Nelms, G Patlewicz
Frontiers in toxicology 2, 580347, 2020
162020
An evaluation of the performance of selected (Q) SARs/expert systems for predicting acute oral toxicity
MD Nelms, AL Karmaus, G Patlewicz
Computational Toxicology 16, 100135, 2020
152020
Editor’s highlight: Negative predictors of carcinogenicity for environmental chemicals
T Hill III, MD Nelms, SW Edwards, M Martin, R Judson, JC Corton, ...
Toxicological Sciences 155 (1), 157-169, 2017
152017
A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions
MD Nelms, CL Mellor, SJ Enoch, RS Judson, G Patlewicz, AM Richard, ...
Computational Toxicology 8, 1-12, 2018
142018
Adverse outcome pathways to support the assessment of chemical mixtures
MD Nelms, JE Simmons, SW Edwards
Chemical Mixtures and Combined Chemical and Nonchemical Stressors: Exposure …, 2018
132018
In silico guidance for in vitro androgen and glucocorticoid receptor ToxCast assays
TEH Allen, MD Nelms, SW Edwards, JM Goodman, S Gutsell, PJ Russell
Environmental Science & Technology 54 (12), 7461-7470, 2020
92020
Mapping Mechanistic Pathways of Acute Oral Systemic Toxicity Using Chemical Structure and Bioactivity Measurements
SW Edwards, M Nelms, VK Hench, J Ponder, K Sullivan
Frontiers in Toxicology 4, 824094, 2022
62022
A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: a case study with dinitroaniline pesticides
JA Leonard, M Nelms, E Craig, M Perron, H Pope-Varsalona, ...
Regulatory Toxicology and Pharmacology 107, 104419, 2019
62019
Linking complex disease and exposure data—insights from an environmental and occupational health study
C Ives, H Pan, SW Edwards, M Nelms, H Covert, MY Lichtveld, ...
Journal of exposure science & environmental epidemiology 33 (1), 12-16, 2023
52023
Structure–activity modeling of mitochondrial dysfunction
S Enoch, C Mellor, M Nelms
Mitochondrial dysfunction caused by drugs and environmental toxicants, 25-34, 2018
52018
Development of new COSMOS oRepeatDose and non-cancer Threshold of Toxicological Concern (TTC) databases to support alternative testing methods for cosmetics related chemicals
C Yang, M Ambrosio, K Arvidson, S Barlow, A Boobis, M Checheva, ...
Toxicology letters 221, S80-S80, 2013
52013
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מאמרים 1–20