| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy, 1-382, 2021 | 9822 | 2021 |
| Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1, 2021 | 2457 | 2021 |
| Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease C Venegas, S Kumar, BS Franklin, T Dierkes, R Brinkschulte, D Tejera, ... Nature 552 (7685), 355-361, 2017 | 917 | 2017 |
| Constitutive phosphorylation of the Parkinson's disease associated α-synuclein M Okochi, J Walter, A Koyama, S Nakajo, M Baba, T Iwatsubo, L Meijer, ... Journal of Biological Chemistry 275 (1), 390-397, 2000 | 737 | 2000 |
| Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent L Meijer, AMWH Thunnissen, AW White, M Garnier, M Nikolic, LH Tsai, ... Chemistry & biology 7 (1), 51-63, 2000 | 601 | 2000 |
| Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine MT Heneka, F Nadrigny, T Regen, A Martinez-Hernandez, ... Proceedings of the National Academy of Sciences 107 (13), 6058-6063, 2010 | 581 | 2010 |
| The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid β protein ending at the 42nd (or 43rd) residue T Tomita, K Maruyama, TC Saido, H Kume, K Shinozaki, S Tokuhiro, ... Proceedings of the National Academy of Sciences 94 (5), 2025-2030, 1997 | 519 | 1997 |
| Nonsteroidal anti-inflammatory drugs repress β-secretase gene promoter activity by the activation of PPARγ M Sastre, I Dewachter, S Rossner, N Bogdanovic, E Rosen, P Borghgraef, ... Proceedings of the National Academy of Sciences 103 (2), 443-448, 2006 | 491 | 2006 |
| TLR2 is a primary receptor for Alzheimer’s amyloid β peptide to trigger neuroinflammatory activation S Liu, Y Liu, W Hao, L Wolf, AJ Kiliaan, B Penke, CE Rübe, J Walter, ... The Journal of Immunology 188 (3), 1098-1107, 2012 | 479 | 2012 |
| Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP [V717I] transgenic mice MT Heneka, M Sastre, L Dumitrescu-Ozimek, I Dewachter, J Walter, ... Journal of neuroinflammation 2, 1-12, 2005 | 418 | 2005 |
| Phosphorylation regulates intracellular trafficking of β-secretase J Walter, R Fluhrer, B Hartung, M Willem, C Kaether, A Capell, S Lammich, ... Journal of Biological Chemistry 276 (18), 14634-14641, 2001 | 390 | 2001 |
| Presenilin-dependent intramembrane proteolysis of CD44 leads to the liberation of its intracellular domain and the secretion of an Aβ-like peptide S Lammich, M Okochi, M Takeda, C Kaether, A Capell, AK Zimmer, ... Journal of Biological Chemistry 277 (47), 44754-44759, 2002 | 389 | 2002 |
| Maturation and pro-peptide cleavage of β-secretase A Capell, H Steiner, M Willem, H Kaiser, C Meyer, J Walter, S Lammich, ... Journal of Biological Chemistry 275 (40), 30849-30854, 2000 | 378 | 2000 |
| Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation MP Kummer, M Hermes, A Delekarte, T Hammerschmidt, S Kumar, ... Neuron 71 (5), 833-844, 2011 | 363 | 2011 |
| Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease DR Thal, J Walter, TC Saido, M Fändrich Acta neuropathologica 129, 167-182, 2015 | 361 | 2015 |
| Sequential proteolytic processing of the triggering receptor expressed on myeloid cells-2 (TREM2) protein by ectodomain shedding and γ-secretase-dependent intramembranous cleavage P Wunderlich, K Glebov, N Kemmerling, NT Tien, H Neumann, J Walter Journal of Biological Chemistry 288 (46), 33027-33036, 2013 | 304 | 2013 |
| The Alzheimer’s disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum J Walter, A Capell, J Grünberg, B Pesold, A Schindzielorz, R Prior, ... Molecular medicine 2, 673-691, 1996 | 288 | 1996 |
| Phosphorylation of amyloid beta (Aβ) peptides–A trigger for formation of toxic aggregates in Alzheimer's disease S Kumar, J Walter Aging (Albany NY) 3 (8), 803, 2011 | 275 | 2011 |
| Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease S Kumar, N Rezaei‐Ghaleh, D Terwel, DR Thal, M Richard, M Hoch, ... The EMBO journal 30 (11), 2255-2265, 2011 | 252 | 2011 |
| Statins promote the degradation of extracellular amyloid β-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion IY Tamboli, E Barth, L Christian, M Siepmann, S Kumar, S Singh, ... Journal of biological chemistry 285 (48), 37405-37414, 2010 | 248 | 2010 |
