Isolates from Alpinia officinarum Hance attenuate LPS induced inflammation in HepG2: Evidence from In Silico and In Vitro Studies HMEH Abdullah A. Elgazar, Nabil M. Selim, Nabil M. Abdel-Hamid, Mohammed A ... Phytotherapy research, 2018 | 79 | 2018 |
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation MA Said, WM Eldehna, A Nocentini, SH Fahim, A Bonardi, AA Elgazar, ... European Journal of Medicinal Chemistry 189, 112019, 2020 | 59 | 2020 |
Chrysophanol, physcion, hesperidin and curcumin modulate the gene expression of pro-inflammatory mediators induced by LPS in HepG2: in silico and molecular studies NM Selim, AA Elgazar, NM Abdel-Hamid, MR Abu El-Magd, A Yasri, ... Antioxidants 8 (9), 371, 2019 | 51 | 2019 |
Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, in vitro and in silico studies DIA Othman, A Hamdi, SS Tawfik, AA Elgazar, AS Mostafa Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2166037, 2023 | 43 | 2023 |
Development of provesicular nanodelivery system of curcumin as a safe and effective antiviral agent: statistical optimization, in vitro characterization, and antiviral … FA Badria, AE Abdelaziz, AH Hassan, AA Elgazar, EA Mazyed Molecules 25 (23), 5668, 2020 | 37 | 2020 |
New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study MM Al-Sanea, A Hamdi, AAB Mohamed, HW El-Shafey, M Moustafa, ... Journal of enzyme inhibition and medicinal chemistry 38 (1), 2166036, 2023 | 32 | 2023 |
Chemical constituents from coconut waste and their in silico evaluation as potential antiviral agents against SARS-CoV-2 AAE Marwa Elsbaey, Mahmoud A A Ibrahim, Fatma Abdel Bar South African Journal of Botany, 2021 | 31 | 2021 |
Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation DM Elimam, AA Elgazar, A Bonardi, M Abdelfadil, A Nocentini, ... European journal of medicinal chemistry 225, 113800, 2021 | 29 | 2021 |
Natural inspired piperine-based ureas and amides as novel antitumor agents towards breast cancer DM Elimam, AA Elgazar, FF El-Senduny, RA El-Domany, FA Badria, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 39-50, 2022 | 28 | 2022 |
Construction of spirooxindole analogues engrafted with indole and pyrazole scaffolds as acetylcholinesterase inhibitors MS Islam, AM Al-Majid, M Azam, VP Verma, A Barakat, M Haukka, ... ACS omega 6 (47), 31539-31556, 2021 | 20 | 2021 |
Development of new thiazolidine-2, 4-dione hybrids as aldose reductase inhibitors endowed with antihyperglycaemic activity: Design, synthesis, biological investigations, and in … A Hamdi, M Yaseen, WA Ewes, MA Bhat, NI Ziedan, HW El-Shafey, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2231170, 2023 | 19 | 2023 |
Insights on the molecular mechanism of anti-inflammatory effect of formula from Islamic traditional medicine: An in-silico study AA Elgazar, HR Knany, MS Ali Journal of Traditional and Complementary Medicine 9 (4), 353-363, 2019 | 19 | 2019 |
Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease MH ElNaggar, AA Elgazar, G Gamal, SM Hamed, ZM Elsayed, ... Journal of enzyme inhibition and medicinal chemistry 38 (1), 2234665, 2023 | 16 | 2023 |
Synthesis of spirooxindole analogs tethered pyrazole scaffold as acetylcholinesterase inhibitors M Shahidul Islam, AM Al‐Majid, M Azam, V Prakash Verma, A Barakat, ... ChemistrySelect 6 (48), 14039-14053, 2021 | 16 | 2021 |
Novel quinazolin-2-yl 1, 2, 3-triazole hybrids as promising multi-target anticancer agents: Design, synthesis, and molecular docking study NFM El Hamaky, A Hamdi, WA Bayoumi, AA Elgazar, MNA Nasr Bioorganic Chemistry 148, 107437, 2024 | 13 | 2024 |
Theophylline-based hybrids as acetylcholinesterase inhibitors endowed with anti-inflammatory activity: synthesis, bioevaluation, in silico and preliminary kinetic studies AA Elgazar, RA El-Domany, WM Eldehna, FA Badria RSC advances 13 (36), 25616-25634, 2023 | 12 | 2023 |
Unraveling the nephroprotective potential of papaverine against cisplatin toxicity through mitigating oxidative stress and inflammation: insights from in silico, in vitro, and … SA Abass, AA Elgazar, SS El-Kholy, AI El-Refaiy, RA Nawaya, MA Bhat, ... Molecules 29 (9), 1927, 2024 | 11 | 2024 |
Bio-evaluation of untapped alkaloids from vinca minor enriched by methyl-jasmonate-induced stress: an integrated approach FF El-Senduny, AA Elgazar, HA Alwasify, A Abed, M Foda, S Abouzeid, ... Planta Medica 89 (10), 964-978, 2023 | 10 | 2023 |
3-Acetyl-11-keto-β-boswellic acid-based hybrids alleviate acetaminophen-induced hepatotoxicity in HepG2 by the regulation of inflammatory and oxidative stress pathways: an … AA Elgazar, RA El-Domany, WM Eldehna, FA Badria ACS omega 8 (42), 39490-39510, 2023 | 7 | 2023 |
Identification of benzothiazoles bearing 1, 3, 4-thiadiazole as antiproliferative hybrids targeting VEGFR-2 and BRAF kinase: design, synthesis, BIO evaluation and in silico study WA Ewes, SS Tawfik, AM Almatary, M Ahmad Bhat, HW El-Shafey, ... Molecules 29 (13), 3186, 2024 | 6 | 2024 |