A biobank of small cell lung cancer CDX models elucidates inter-and intratumoral phenotypic heterogeneity KL Simpson, R Stoney, KK Frese, N Simms, W Rowe, SP Pearce, ... Nature Cancer 1 (4), 437-451, 2020 | 160 | 2020 |
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape CG Knight, M Platt, W Rowe, DC Wedge, F Khan, PJR Day, A McShea, ... Nucleic acids research 37 (1), e6-e6, 2009 | 141 | 2009 |
Global mRNA selection mechanisms for translation initiation J Costello, LM Castelli, W Rowe, CJ Kershaw, D Talavera, ... Genome biology 16, 1-21, 2015 | 121 | 2015 |
Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up … LM Castelli, J Lui, SG Campbell, W Rowe, LAH Zeef, LEA Holmes, ... Molecular biology of the cell 22 (18), 3379-3393, 2011 | 106 | 2011 |
Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states A Adamson, C Boddington, P Downton, W Rowe, J Bagnall, C Lam, ... Nature communications 7 (1), 12057, 2016 | 84 | 2016 |
Analysis of a complete DNA–protein affinity landscape W Rowe, M Platt, DC Wedge, PJ Day, DB Kell, J Knowles Journal of The Royal Society Interface 7 (44), 397-408, 2010 | 76 | 2010 |
Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells R Brignall, P Cauchy, SL Bevington, B Gorman, AO Pisco, J Bagnall, ... The Journal of Immunology 199 (8), 2652-2667, 2017 | 70 | 2017 |
Temperature regulates NF-κB dynamics and function through timing of A20 transcription CV Harper, DJ Woodcock, C Lam, M Garcia-Albornoz, A Adamson, ... Proceedings of the National Academy of Sciences 115 (22), E5243-E5249, 2018 | 69 | 2018 |
Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins AG Cridge, LM Castelli, JB Smirnova, JN Selley, W Rowe, SJ Hubbard, ... Nucleic acids research 38 (22), 8039-8050, 2010 | 65 | 2010 |
Aptamer evolution for array-based diagnostics M Platt, W Rowe, DC Wedge, DB Kell, J Knowles, PJR Day Analytical biochemistry 390 (2), 203-205, 2009 | 60 | 2009 |
Integrated multi-omics analyses reveal the pleiotropic nature of the control of gene expression by Puf3p CJ Kershaw, JL Costello, D Talavera, W Rowe, LM Castelli, PFG Sims, ... Scientific reports 5 (1), 15518, 2015 | 59 | 2015 |
Rapid prototyping of microbial production strains for the biomanufacture of potential materials monomers CJ Robinson, P Carbonell, AJ Jervis, C Yan, KA Hollywood, MS Dunstan, ... Metabolic Engineering 60, 168-182, 2020 | 58 | 2020 |
Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation J Bagnall, C Boddington, H England, R Brignall, P Downton, Z Alsoufi, ... Science signaling 11 (540), eaaf3998, 2018 | 57 | 2018 |
3D printed microfluidic device with integrated optical sensing for particle analysis SM Hampson, W Rowe, SDR Christie, M Platt Sensors and Actuators B: Chemical 256, 1030-1037, 2018 | 56 | 2018 |
The 4E-BP Caf20p mediates both eIF4E-dependent and independent repression of translation LM Castelli, D Talavera, CJ Kershaw, SS Mohammad-Qureshi, ... PLoS genetics 11 (5), e1005233, 2015 | 49 | 2015 |
The yeast La related protein Slf1p is a key activator of translation during the oxidative stress response CJ Kershaw, JL Costello, LM Castelli, D Talavera, W Rowe, PFG Sims, ... PLoS genetics 11 (1), e1004903, 2015 | 46 | 2015 |
Quantitative dynamic imaging of immune cell signalling using lentiviral gene transfer J Bagnall, C Boddington, J Boyd, R Brignall, W Rowe, NA Jones, ... Integrative Biology 7 (6), 713-725, 2015 | 43 | 2015 |
Dynamic changes in eIF4F-mRNA interactions revealed by global analyses of environmental stress responses JL Costello, CJ Kershaw, LM Castelli, D Talavera, W Rowe, PFG Sims, ... Genome Biology 18, 1-18, 2017 | 42 | 2017 |
Puf3p induces translational repression of genes linked to oxidative stress W Rowe, CJ Kershaw, LM Castelli, JL Costello, MP Ashe, CM Grant, ... Nucleic acids research 42 (2), 1026-1041, 2013 | 41 | 2013 |
In silico modelling of directed evolution: Implications for experimental design and stepwise evolution DC Wedge, W Rowe, DB Kell, J Knowles Journal of Theoretical Biology 257 (1), 131-141, 2009 | 39 | 2009 |