Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine S Keipert, M Ost, K Johann, F Imber, M Jastroch, EM Van Schothorst, ... American Journal of Physiology-Endocrinology and Metabolism 306 (5), E469-E482, 2014 | 256 | 2014 |
Regulation of myokine expression: Role of exercise and cellular stress M Ost, V Coleman, J Kasch, S Klaus Free Radical Biology and Medicine 98, 78-89, 2016 | 168 | 2016 |
Long-term cold adaptation does not require FGF21 or UCP1 S Keipert, M Kutschke, M Ost, T Schwarzmayr, EM van Schothorst, ... Cell metabolism 26 (2), 437-446. e5, 2017 | 124 | 2017 |
Uncoupling protein-1 is not leaky IG Shabalina, M Ost, N Petrovic, M Vrbacky, J Nedergaard, B Cannon Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 773-784, 2010 | 112 | 2010 |
Muscle‐derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress M Ost, C Igual Gil, V Coleman, S Keipert, S Efstathiou, V Vidic, M Weyers, ... EMBO reports 21 (3), e48804, 2020 | 103 | 2020 |
Stress-induced FGF21 and GDF15 in obesity and obesity resistance S Keipert, M Ost Trends in Endocrinology & Metabolism 32 (11), 904-915, 2021 | 92 | 2021 |
Mitochondrial uncoupling and longevity–A role for mitokines? S Klaus, M Ost Experimental gerontology 130, 110796, 2020 | 85 | 2020 |
Sustainable food protein supply reconciling human and ecosystem health: A Leibniz Position I Weindl, M Ost, P Wiedmer, M Schreiner, S Neugart, R Klopsch, ... Global Food Security 25, 100367, 2020 | 84 | 2020 |
Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action M Ost, V Coleman, A Voigt, EM van Schothorst, S Keipert, I van der Stelt, ... Molecular metabolism 5 (2), 79-90, 2016 | 74 | 2016 |
Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux M Ost, S Keipert, EM van Schothorst, V Donner, I van der Stelt, AP Kipp, ... The FASEB Journal 29 (4), 1314-1328, 2015 | 73 | 2015 |
High‐protein diet more effectively reduces hepatic fat than low‐protein diet despite lower autophagy and FGF21 levels C Xu, M Markova, N Seebeck, A Loft, S Hornemann, T Gantert, S Kabisch, ... Liver International 40 (12), 2982-2997, 2020 | 70 | 2020 |
Targeted mitochondrial uncoupling beyond UCP1–the fine line between death and metabolic health M Ost, S Keipert, S Klaus Biochimie 134, 77-85, 2017 | 53 | 2017 |
Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity J Münzker, N Haase, A Till, R Sucher, SB Haange, L Nemetschke, T Gnad, ... Microbiome 10 (1), 96, 2022 | 48 | 2022 |
Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system S Keipert, M Ost, A Chadt, A Voigt, V Ayala, M Portero-Otín, R Pamplona, ... American Journal of Physiology-Endocrinology and Metabolism 304 (5), E495-E506, 2013 | 48 | 2013 |
Role of GDF15 in active lifestyle induced metabolic adaptations and acute exercise response in mice CI Gil, M Ost, J Kasch, S Schumann, S Heider, S Klaus Scientific reports 9 (1), 20120, 2019 | 41 | 2019 |
Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling V Coleman, P Sa-Nguanmoo, J Koenig, TJ Schulz, T Grune, S Klaus, ... Scientific reports 8 (1), 1-12, 2018 | 37 | 2018 |
Associations between serum GDF15 concentrations, muscle mass, and strength show sex-specific differences in older hospital patients C Herpich, K Franz, M Ost, L Otten, V Coleman, S Klaus, U Müller-Werdan, ... Rejuvenation Research 24 (1), 14-19, 2021 | 33 | 2021 |
Mitochondria-targeted dodecyltriphenylphosphonium (C12TPP) combats high-fat-diet-induced obesity in mice AV Kalinovich, CL Mattsson, MR Youssef, N Petrovic, M Ost, ... International Journal of Obesity 40 (12), 1864-1874, 2016 | 31 | 2016 |
Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity M Ost, F Werner, J Dokas, S Klaus, A Voigt PloS one 9 (4), e94689, 2014 | 31 | 2014 |
Assessing inflammageing U Müller-Werdan, S Nuding, M Ost Current Opinion in Clinical Nutrition & Metabolic Care 20 (5), 346-348, 2017 | 24 | 2017 |