גישה ציבורית

C9ORF72 protein function and immune dysregulation in amyotrophic lateral sclerosis‏

JD Lai, JK Ichida‏

Neuroscience Letters 713, 134523, 2019‏

הרשאות: US National Institutes of Health‏

Repairing the blood-brain barrier‏

AP McMahon, JK Ichida‏

Science 375 (6582), 715-716, 2022‏

הרשאות: US National Science Foundation, US National Institutes of Health‏

[P3–167]: DEVELOPMENT OF AN IPSC‐BASED BIOMARKER STRATEGY TO IDENTIFY NEUROREGENERATIVE RESPONDERS TO ALLOPREGNANOLONE‏

CM Solinsky, JA Park, HC Chui, M Blurton‐Jones, JK Ichida, ...‏

Alzheimer's & Dementia 13 (7S_Part_20), P998-P998, 2017‏

הרשאות: US National Institutes of Health‏

P3‐039: Early‐stage development of ips‐based biomarkers to identify patient population with a regenerative profile responsive to allopregnanolone‏

CM Solinsky, MK Desai, J Yao, V Hennes, H Chang Chui, JK Ichida, ...‏

Alzheimer's & Dementia 11 (7S_Part_13), P633-P634, 2015‏

הרשאות: US National Institutes of Health‏

P3‐138: Development of IPSC‐Based Biomarkers to Identify the Patient Population Responsive to Allopregnanolone‏

CM Solinsky, V Hennes, M Blurton-Jones, JA Park, HC Chui, JK Ichida, ...‏

Alzheimer's & Dementia 12, P871-P871, 2016‏

הרשאות: US National Institutes of Health‏

זמינים באתר כלשהו: 61

A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog‏

JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ...‏

Cell stem cell 5 (5), 491-503, 2009‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute, John D …‏

Conversion of mouse and human fibroblasts into functional spinal motor neurons‏

EY Son, JK Ichida, BJ Wainger, JS Toma, VF Rafuse, CJ Woolf, K Eggan‏

Cell stem cell 9 (3), 205-218, 2011‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute‏

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons‏

Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ...‏

Nature medicine 24 (3), 313-325, 2018‏

הרשאות: US Department of Defense, US National Institutes of Health, Netherlands …‏

Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death‏

X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ...‏

Neuron 84 (6), 1213-1225, 2014‏

הרשאות: US National Institutes of Health‏

[PDF] cell.com

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1‏

E Kiskinis, J Sandoe, LA Williams, GL Boulting, R Moccia, BJ Wainger, ...‏

Cell stem cell 14 (6), 781-795, 2014‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute‏

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance‏

Z Zhao, AP Sagare, Q Ma, MR Halliday, P Kong, K Kisler, EA Winkler, ...‏

Nature neuroscience 18 (7), 978-987, 2015‏

הרשאות: US National Institutes of Health‏

CLP1 links tRNA metabolism to progressive motor-neuron loss‏

T Hanada, S Weitzer, B Mair, C Bernreuther, BJ Wainger, J Ichida, ...‏

Nature 495 (7442), 474-480, 2013‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute, Austrian …‏

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity‏

NJ Kramer, MS Haney, DW Morgens, A Jovičić, J Couthouis, A Li, J Ousey, ...‏

Nature genetics 50 (4), 603-612, 2018‏

הרשאות: US National Science Foundation, US Department of Defense, US National …‏

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts‏

BJ Wainger, ED Buttermore, JT Oliveira, C Mellin, S Lee, WA Saber, ...‏

Nature neuroscience 18 (1), 17-24, 2015‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute‏

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR)‏

M Maor-Nof, Z Shipony, R Lopez-Gonzalez, L Nakayama, YJ Zhang, ...‏

Cell 184 (3), 689-708. e20, 2021‏

הרשאות: US Department of Defense, US National Institutes of Health, Chan Zuckerberg …‏

[HTML] nature.com

A CRISPRi/a platform in human iPSC-derived microglia uncovers regulators of disease states‏

NM Dräger, SM Sattler, CTL Huang, OM Teter, K Leng, SH Hashemi, ...‏

Nature neuroscience 25 (9), 1149-1162, 2022‏

הרשאות: US National Science Foundation, US National Institutes of Health, Chan …‏

[PDF] acs.org

Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication‏

S Rajamani, JK Ichida, T Antal, DA Treco, K Leu, MA Nowak, JW Szostak, ...‏

Journal of the American Chemical Society 132 (16), 5880-5885, 2010‏

הרשאות: US National Institutes of Health, Howard Hughes Medical Institute‏

[PDF] cell.com

ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids‏

KR Bowles, MC Silva, K Whitney, T Bertucci, JE Berlind, JD Lai, JC Garza, ...‏

Cell 184 (17), 4547-4563. e17, 2021‏

הרשאות: US Department of Defense, US National Institutes of Health‏

[PDF] nih.gov

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis‏

SA Patten, D Aggad, J Martinez, E Tremblay, J Petrillo, GAB Armstrong, ...‏

JCI insight 2 (22), e97152, 2017‏

הרשאות: US Department of Defense, US National Institutes of Health, Canadian …‏