| Specificity Determinants of Recruitment Peptides Bound to Phospho-CDK2/Cyclin A, ED Lowe, I Tews, KY Cheng, NR Brown, S Gul, MEM Noble, SJ Gamblin, ... Biochemistry 41 (52), 15625-15634, 2002 | 219 | 2002 |
| A classical enzyme active center motif lacks catalytic competence until modulated electrostatically S Pinitglang, AB Watts, M Patel, JD Reid, MA Noble, S Gul, A Bokth, ... Biochemistry 36 (33), 9968-9982, 1997 | 128 | 1997 |
| Identification of small-molecule frequent hitters from AlphaScreen high-throughput screens K Schorpp, I Rothenaigner, E Salmina, J Reinshagen, T Low, JK Brenke, ... Journal of biomolecular screening 19 (5), 715-726, 2014 | 105 | 2014 |
| Characteristics of the cancer stem cell niche and therapeutic strategies F Ju, MM Atyah, N Horstmann, S Gul, R Vago, CJ Bruns, Y Zhao, QZ Dong, ... Stem Cell Research & Therapy 13 (1), 233, 2022 | 83 | 2022 |
| Bone marrow mononuclear cells activate angiogenesis via gap junction–mediated cell-cell interaction A Kikuchi-Taura, Y Okinaka, Y Takeuchi, Y Ogawa, M Maeda, Y Kataoka, ... Stroke 51 (4), 1279-1289, 2020 | 74 | 2020 |
| Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs C Borsari, R Luciani, C Pozzi, I Poehner, S Henrich, M Trande, ... Journal of medicinal chemistry 59 (16), 7598-7616, 2016 | 57 | 2016 |
| Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity F Di Pisa, G Landi, L Dello Iacono, C Pozzi, C Borsari, S Ferrari, ... Molecules 22 (3), 426, 2017 | 55 | 2017 |
| A bioluminogenic HDAC activity assay: validation and screening F Halley, J Reinshagen, B Ellinger, M Wolf, AL Niles, NJ Evans, ... Journal of biomolecular screening 16 (10), 1227-1235, 2011 | 53 | 2011 |
| Protein–protein interaction modulator drug discovery: past efforts and future opportunities using a rich source of low-and high-throughput screening assays S Gul, K Hadian Expert Opinion on Drug Discovery 9 (12), 1393-1404, 2014 | 48 | 2014 |
| Aryl thiosemicarbazones for the treatment of trypanosomatidic infections P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ... European Journal of Medicinal Chemistry 146, 423-434, 2018 | 43 | 2018 |
| Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158 S Gul, S Hussain, MP Thomas, M Resmini, CS Verma, EW Thomas, ... Biochemistry 47 (7), 2025-2035, 2008 | 39 | 2008 |
| Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques … MA NOBLE, S GUL, CS VERMA, K BROCKLEHURST Biochemical Journal 351 (3), 723-733, 2000 | 38 | 2000 |
| Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display … E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ... European Journal of Medicinal Chemistry 141, 138-148, 2017 | 37 | 2017 |
| Gap junction-mediated cell-cell interaction between transplanted mesenchymal stem cells and vascular endothelium in stroke A Kikuchi-Taura, Y Okinaka, O Saino, Y Takeuchi, Y Ogawa, T Kimura, ... Stem Cells 39 (7), 904-912, 2021 | 36 | 2021 |
| Epigenetic assays for chemical biology and drug discovery S Gul Clinical epigenetics 9 (1), 41, 2017 | 36 | 2017 |
| Tegaserod mimics the neurostimulatory glycan polysialic acid and promotes nervous system repair J Bushman, B Mishra, M Ezra, S Gul, C Schulze, S Chaudhury, D Ripoll, ... Neuropharmacology 79, 456-466, 2014 | 36 | 2014 |
| Enhancement of benzothiazoles as pteridine reductase-1 inhibitors for the treatment of trypanosomatidic infections P Linciano, C Pozzi, LD Iacono, F di Pisa, G Landi, A Bonucci, S Gul, ... Journal of Medicinal Chemistry 62 (8), 3989-4012, 2019 | 34 | 2019 |
| The target residence time of antihistamines determines their antagonism of the G protein-coupled histamine H1 receptor R Bosma, G Witt, LAI Vaas, I Josimovic, P Gribbon, HF Vischer, S Gul, ... Frontiers in Pharmacology 8, 667, 2017 | 34 | 2017 |
| Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery P Linciano, A Dawson, I Pöhner, DM Costa, MS Sá, A Cordeiro-da-Silva, ... ACS omega 2 (9), 5666-5683, 2017 | 33 | 2017 |
| Exemplification of the challenges associated with utilising fluorescence intensity based assays in discovery S Gul, P Gribbon Expert Opinion on Drug Discovery 5 (7), 681-690, 2010 | 33 | 2010 |
