| Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ... Nature neuroscience 22 (3), 401-412, 2019 | 1383 | 2019 |
| NAD+ in brain aging and neurodegenerative disorders S Lautrup, DA Sinclair, MP Mattson, EF Fang Cell metabolism 30 (4), 630-655, 2019 | 601 | 2019 |
| NAD+ in aging: molecular mechanisms and translational implications EF Fang, S Lautrup, Y Hou, TG Demarest, DL Croteau, MP Mattson, ... Trends in molecular medicine 23 (10), 899-916, 2017 | 515 | 2017 |
| NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, ... Proceedings of the National Academy of Sciences 115 (8), E1876-E1885, 2018 | 457 | 2018 |
| Mitophagy in neurodegeneration and aging EM Fivenson, S Lautrup, N Sun, M Scheibye-Knudsen, T Stevnsner, ... Neurochemistry international 109, 202-209, 2017 | 370 | 2017 |
| Mitophagy and neuroprotection G Lou, K Palikaras, S Lautrup, M Scheibye-Knudsen, N Tavernarakis, ... Trends in molecular medicine 26 (1), 8-20, 2020 | 362 | 2020 |
| NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING Y Hou, Y Wei, S Lautrup, B Yang, Y Wang, S Cordonnier, MP Mattson, ... Proceedings of the National Academy of Sciences 118 (37), e2011226118, 2021 | 329 | 2021 |
| New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary T Schmauck-Medina, A Molière, S Lautrup, J Zhang, S Chlopicki, ... Aging (Albany NY) 14 (16), 6829, 2022 | 269 | 2022 |
| NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ... Nature communications 10 (1), 5284, 2019 | 226 | 2019 |
| Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow C Xie, XX Zhuang, Z Niu, R Ai, S Lautrup, S Zheng, Y Jiang, R Han, ... Nature Biomedical Engineering 6 (1), 76-93, 2022 | 200 | 2022 |
| Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease S Lautrup, G Lou, Y Aman, H Nilsen, J Tao, EF Fang Neurochemistry International 129, 104469, 2019 | 98 | 2019 |
| DNA damage-induced neurodegeneration in accelerated ageing and Alzheimer’s disease H Wang, S Lautrup, D Caponio, J Zhang, EF Fang International Journal of Molecular Sciences 22 (13), 6748, 2021 | 47 | 2021 |
| Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing BC Gilmour, R Gudmundsrud, J Frank, A Hov, S Lautrup, Y Aman, ... Mechanisms of Ageing and Development 186, 111208, 2020 | 46 | 2020 |
| The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications Y Aman, J Frank, SH Lautrup, A Matysek, Z Niu, G Yang, L Shi, ... Mechanisms of ageing and development 185, 111194, 2020 | 44 | 2020 |
| Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases S Lautrup, D Caponio, HH Cheung, C Piccoli, T Stevnsner, WY Chan, ... Biogerontology 20, 255-269, 2019 | 35 | 2019 |
| Roles of NAD+ in Health and Aging S Lautrup, Y Hou, EF Fang, VA Bohr Cold Spring Harbor Perspectives in Medicine 14 (1), a041193, 2024 | 16 | 2024 |
| A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging FW Pun, GHD Leung, HW Leung, J Rice, T Schmauck‐Medina, S Lautrup, ... Aging Cell 22 (12), e14017, 2023 | 16 | 2023 |
| WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome Y Tian, W Wang, S Lautrup, H Zhao, X Li, PWN Law, ND Dinh, EF Fang, ... Nature communications 13 (1), 5456, 2022 | 13 | 2022 |
| Two Cockayne Syndrome patients with a novel splice site mutation–clinical and metabolic analyses I Sanchez-Roman, S Lautrup, MD Aamann, EG Neilan, JR Østergaard, ... Mechanisms of Ageing and Development 175, 7-16, 2018 | 12 | 2018 |
| Crosstalk among DNA damage, mitochondrial dysfunction, impaired mitophagy, stem cell attrition, and senescence in the accelerated ageing disorder Werner syndrome R Gudmundsrud, TH Skjånes, BC Gilmour, D Caponio, S Lautrup, ... Cytogenetic and Genome Research 161 (6-7), 297-304, 2021 | 9 | 2021 |