| Two supporting factors greatly improve the efficiency of human iPSC generation Y Zhao, X Yin, H Qin, F Zhu, H Liu, W Yang, Q Zhang, C Xiang, P Hou, ... Cell stem cell 3 (5), 475-479, 2008 | 639 | 2008 |
| A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 562 | 2015 |
| Repression of the antioxidant NRF2 pathway in premature aging N Kubben, W Zhang, L Wang, TC Voss, J Yang, J Qu, GH Liu, T Misteli Cell 165 (6), 1361-1374, 2016 | 504 | 2016 |
| Single-cell transcriptomic atlas of primate ovarian aging S Wang, Y Zheng, J Li, Y Yu, W Zhang, M Song, Z Liu, Z Min, H Hu, Y Jing, ... Cell 180 (3), 585-600. e19, 2020 | 444 | 2020 |
| Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules Y Li, Q Zhang, X Yin, W Yang, Y Du, P Hou, J Ge, C Liu, W Zhang, ... Cell research 21 (1), 196-204, 2011 | 418 | 2011 |
| The ageing epigenome and its rejuvenation W Zhang, J Qu, GH Liu, JCI Belmonte Nature reviews Molecular cell biology 21 (3), 137-150, 2020 | 411 | 2020 |
| Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 GH Liu, J Qu, K Suzuki, E Nivet, M Li, N Montserrat, F Yi, X Xu, S Ruiz, ... Nature 491 (7425), 603-607, 2012 | 411 | 2012 |
| SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2 H Pan, D Guan, X Liu, J Li, L Wang, J Wu, J Zhou, W Zhang, R Ren, ... Cell research 26 (2), 190-205, 2016 | 326 | 2016 |
| Epigenetic regulation of aging: implications for interventions of aging and diseases K Wang, H Liu, Q Hu, L Wang, J Liu, Z Zheng, W Zhang, J Ren, F Zhu, ... Signal transduction and targeted therapy 7 (1), 374, 2022 | 323 | 2022 |
| Caloric restriction reprograms the single-cell transcriptional landscape of Rattus norvegicus aging S Ma, S Sun, L Geng, M Song, W Wang, Y Ye, Q Ji, Z Zou, SI Wang, X He, ... Cell 180 (5), 984-1001. e22, 2020 | 297 | 2020 |
| The landscape of aging Y Cai, W Song, J Li, Y Jing, C Liang, L Zhang, X Zhang, W Zhang, B Liu, ... Science China Life Sciences 65 (12), 2354-2454, 2022 | 278 | 2022 |
| A single-cell transcriptomic atlas of human skin aging Z Zou, X Long, Q Zhao, Y Zheng, M Song, S Ma, Y Jing, SI Wang, Y He, ... Developmental cell 56 (3), 383-397. e8, 2021 | 250 | 2021 |
| Epigenetic modifications in cardiovascular aging and diseases W Zhang, M Song, J Qu, GH Liu Circulation research 123 (7), 773-786, 2018 | 243 | 2018 |
| A human circulating immune cell landscape in aging and COVID-19 Y Zheng, X Liu, W Le, L Xie, H Li, W Wen, S Wang, S Ma, Z Huang, J Ye, ... Protein & cell 11 (10), 740-770, 2020 | 233 | 2020 |
| Resurrection of endogenous retroviruses during aging reinforces senescence X Liu, Z Liu, Z Wu, J Ren, Y Fan, L Sun, G Cao, Y Niu, B Zhang, Q Ji, ... Cell 186 (2), 287-304. e26, 2023 | 202 | 2023 |
| Biomarkers of aging Aging Biomarker Consortium, H Bao, J Cao, M Chen, M Chen, W Chen, ... Science China Life Sciences 66 (5), 893-1066, 2023 | 199 | 2023 |
| SIRT6 deficiency results in developmental retardation in cynomolgus monkeys W Zhang, H Wan, G Feng, J Qu, J Wang, Y Jing, R Ren, Z Liu, L Zhang, ... Nature 560 (7720), 661-665, 2018 | 171 | 2018 |
| PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype S Duan, G Yuan, X Liu, R Ren, J Li, W Zhang, J Wu, X Xu, L Fu, Y Li, ... Nature communications 6 (1), 10068, 2015 | 169 | 2015 |
| Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis L Fu, Y Hu, M Song, Z Liu, W Zhang, FX Yu, J Wu, S Wang, ... PLoS biology 17 (4), e3000201, 2019 | 148 | 2019 |
| A single-cell transcriptomic landscape of the lungs of patients with COVID-19 S Wang, X Yao, S Ma, Y Ping, Y Fan, S Sun, Z He, Y Shi, L Sun, S Xiao, ... Nature cell biology 23 (12), 1314-1328, 2021 | 145 | 2021 |