Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ... Cancer research 71 (9), 3364-3376, 2011 | 792 | 2011 |
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products O Kleifeld, A Doucet, U auf dem Keller, A Prudova, O Schilling, ... Nature biotechnology 28 (3), 281-288, 2010 | 576 | 2010 |
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound S Braun, C Hanselmann, MG Gassmann, U auf dem Keller, ... Molecular and cellular biology 22 (15), 5492-5505, 2002 | 384 | 2002 |
Impaired liver regeneration in Nrf2 knockout mice: role of ROS‐mediated insulin/IGF‐1 resistance TA Beyer, W Xu, D Teupser, U auf dem Keller, P Bugnon, E Hildt, J Thiery, ... The EMBO journal 27 (1), 212-223, 2008 | 330 | 2008 |
Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics A Prudova, U auf dem Keller, GS Butler, CM Overall Molecular & Cellular Proteomics 9 (5), 894-911, 2010 | 324 | 2010 |
Quantitative single-cell proteomics as a tool to characterize cellular hierarchies EM Schoof, B Furtwängler, N Üresin, N Rapin, S Savickas, C Gentil, ... Nature communications 12 (1), 3341, 2021 | 302 | 2021 |
Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates O Kleifeld, A Doucet, A Prudova, M Gioia, JN Kizhakkedathu, CM Overall Nature protocols 6 (10), 1578-1611, 2011 | 302 | 2011 |
Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic … U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ... Matrix biology 49, 37-60, 2016 | 228 | 2016 |
Reactive oxygen species and their detoxification in healing skin wounds U Auf Dem Keller, A Kümin, S Braun, S Werner Journal of Investigative Dermatology Symposium Proceedings 11 (1), 106-111, 2006 | 163 | 2006 |
Proteomic analyses reveal an acidic prime side specificity for the astacin metalloprotease family reflected by physiological substrates C Becker-Pauly, O Barré, O Schilling, U auf dem Keller, A Ohler, C Broder, ... Molecular & Cellular Proteomics 10 (9), 2011 | 145 | 2011 |
Epithelial–mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis Y Lou, O Preobrazhenska, U auf dem Keller, M Sutcliffe, L Barclay, ... Developmental Dynamics 237 (10), 2755-2768, 2008 | 141 | 2008 |
Toward [18F]-Labeled Aryltrifluoroborate Radiotracers: In Vivo Positron Emission Tomography Imaging of Stable Aryltrifluoroborate Clearance in Mice R Ting, C Harwig, U auf dem Keller, S McCormick, P Austin, CM Overall, ... Journal of the American Chemical Society 130 (36), 12045-12055, 2008 | 127 | 2008 |
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10 T Jefferson, U Auf dem Keller, C Bellac, VV Metz, C Broder, J Hedrich, ... Cellular and Molecular Life Sciences 70, 309-333, 2013 | 125 | 2013 |
Metalloprotease meprin β generates nontoxic N-terminal amyloid precursor protein fragments in vivo T Jefferson, M Čaušević, U auf dem Keller, O Schilling, S Isbert, R Geyer, ... Journal of Biological Chemistry 286 (31), 27741-27750, 2011 | 124 | 2011 |
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing U auf dem Keller, M Huber, TA Beyer, A Kümin, C Siemes, S Braun, ... Molecular and cellular biology 26 (10), 3773-3784, 2006 | 122 | 2006 |
Fibroblast growth factors in epithelial repair and cytoprotection S Braun, U auf dem Keller, H Steiling, S Werner Philosophical Transactions of the Royal Society of London. Series B …, 2004 | 112 | 2004 |
Systems-level analysis of proteolytic events in increased vascular permeability and complement activation in skin inflammation U auf dem Keller, A Prudova, U Eckhard, B Fingleton, CM Overall Science signaling 6 (258), rs2, 2013 | 111 | 2013 |
Macrophage matrix metalloproteinase-12 dampens inflammation and neutrophil influx in arthritis CL Bellac, A Dufour, MJ Krisinger, A Loonchanta, AE Starr, ... Cell Reports 9 (2), 618-632, 2014 | 110 | 2014 |
Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis M Schafer, S Dutsch, U Auf dem Keller, F Navid, A Schwarz, DA Johnson, ... Genes Dev 24 (10), 1045-1058, 2010 | 108 | 2010 |
Caspase-1 activity is required for UVB-induced apoptosis of human keratinocytes G Sollberger, GE Strittmatter, S Grossi, M Garstkiewicz, U Auf dem Keller, ... Journal of Investigative Dermatology 135 (5), 1395-1404, 2015 | 103 | 2015 |