Targeting folate receptor alpha for cancer treatment A Cheung, HJ Bax, DH Josephs, KM Ilieva, G Pellizzari, J Opzoomer, ... Oncotarget 7 (32), 52553, 2016 | 476 | 2016 |
Cytotoxic chemotherapy as an immune stimulus: a molecular perspective on turning up the immunological heat on cancer JW Opzoomer, D Sosnowska, JE Anstee, JF Spicer, JN Arnold Frontiers in immunology 10, 1654, 2019 | 141 | 2019 |
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis T Muliaditan, J Caron, M Okesola, JW Opzoomer, P Kosti, M Georgouli, ... Nature communications 9 (1), 2951, 2018 | 116 | 2018 |
Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors P Kosti, JW Opzoomer, KI Larios-Martinez, R Henley-Smith, ... Cell reports medicine 2 (4), 2021 | 113 | 2021 |
Anti-folate receptor alpha–directed antibody therapies restrict the growth of triple-negative breast cancer A Cheung, J Opzoomer, KM Ilieva, P Gazinska, RM Hoffmann, H Mirza, ... Clinical Cancer Research 24 (20), 5098-5111, 2018 | 88 | 2018 |
B cells and the humoral response in melanoma: the overlooked players of the tumor microenvironment G Chiaruttini, S Mele, J Opzoomer, S Crescioli, KM Ilieva, KE Lacy, ... Oncoimmunology 6 (4), e1294296, 2017 | 76 | 2017 |
Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer T Muliaditan, JW Opzoomer, J Caron, M Okesola, P Kosti, S Lall, ... Clinical Cancer Research, clincanres. 2587.2017, 2018 | 69 | 2018 |
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression JW Opzoomer, JE Anstee, I Dean, EJ Hill, I Bouybayoune, J Caron, ... Science advances 7 (45), eabg9518, 2021 | 50 | 2021 |
Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses MR Zapatero, A Tong, JW Opzoomer, R O’Sullivan, FC Rodriguez, J Sufi, ... Cell 186 (25), 5606-5619. e24, 2023 | 33 | 2023 |
LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer JE Anstee, KT Feehan, JW Opzoomer, I Dean, HP Muller, M Bahri, ... Developmental cell 58 (17), 1548-1561. e10, 2023 | 22 | 2023 |
ImmunoCluster provides a computational framework for the nonspecialist to profile high-dimensional cytometry data JW Opzoomer, JA Timms, K Blighe, TP Mourikis, N Chapuis, R Bekoe, ... Elife 10, e62915, 2021 | 19 | 2021 |
A community effort to track commercial single-cell and spatial’omic technologies and business trends J De Jonghe, JW Opzoomer, A Vilas-Zornoza, P Crane, BS Nilges, ... nature biotechnology 42 (7), 1017-1023, 2024 | 4 | 2024 |
Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer JE Anstee, JW Opzoomer, I Dean, HP Muller, M Bahri, K Liakath-Ali, Z Liu, ... bioRxiv, 2022.02. 03.478952, 2022 | 3 | 2022 |
ImmunoCluster: A computational framework for the non-specialist to immune profile cellular heterogeneity using liquid and imaging mass, and flow cytometry datasets JW Opzoomer, J Timms, K Blighe, TP Mourikis, N Chapuis, R Bekoe, ... bioRxiv, 2020.09. 09.289033, 2020 | 3 | 2020 |
Perivascular tumor-associated macrophages and their role in cancer progression M Bahri, JE Anstee, JW Opzoomer, JN Arnold Essays in Biochemistry 67 (6), 919-928, 2023 | 2 | 2023 |
Predicting progression-free survival after systemic therapy in advanced head and neck cancer: Bayesian regression and model development PR Barber, R Mustapha, F Flores-Borja, G Alfano, K Ng, G Weitsman, ... Elife 11, e73288, 2022 | 2 | 2022 |
Immunocluster: a computational tool to explore the immune profile and cellular heterogeneity of hematological diseases using liquid and imaging mass, and flow cytometry data JA Timms, JW Opzoomer, K Blighe, B Apollonio, T Mourikis, N Chapuis, ... Blood 136, 9-10, 2020 | 2 | 2020 |
scTrends: A living review of commercial single-cell and spatial'omic technologies J De Jonghe, JW Opzoomer, A Vilas-Zornoza, BS Nilges, P Crane, ... Cell Genomics 4 (12), 2024 | 1 | 2024 |
SIGNAL-seq: Multimodal Single-cell Inter-and Intra-cellular Signalling Analysis JW Opzoomer, R O’Sullivan, J Sufi, R Madsen, X Qin, E Basiarz, CJ Tape bioRxiv, 2024.02. 23.581433, 2024 | 1 | 2024 |
No Foundations without Foundations--Why semi-mechanistic models are essential for regulatory biology L Kovačević, T Gaudelet, J Opzoomer, H Triendl, J Whittaker, C Uhler, ... arXiv preprint arXiv:2501.19178, 2025 | | 2025 |