The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation C Pastori, P Kapranov, C Penas, V Peschansky, CH Volmar, JN Sarkaria, ... Proceedings of the National Academy of Sciences 112 (27), 8326-8331, 2015 | 223 | 2015 |
RETRACTED: Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model KJ Janczura, CH Volmar, GC Sartor, SJ Rao, NR Ricciardi, G Lambert, ... Proceedings of the National Academy of Sciences 115 (47), E11148-E11157, 2018 | 194 | 2018 |
Histone deacetylases (HDACs) and brain function CH Volmar, C Wahlestedt Neuroepigenetics, 2014 | 188 | 2014 |
Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier D Paris, C Bachmeier, N Patel, A Quadros, CH Volmar, V Laporte, ... Molecular Medicine 17, 149-162, 2011 | 168 | 2011 |
BET bromodomain proteins are required for glioblastoma cell proliferation C Pastori, M Daniel, C Penas, CH Volmar, AL Johnstone, SP Brothers, ... Epigenetics 9 (4), 611-620, 2014 | 164 | 2014 |
The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers J Long, B Li, J Rodriguez-Blanco, C Pastori, CH Volmar, C Wahlestedt, ... Journal of Biological Chemistry 289 (51), 35494-35502, 2014 | 125 | 2014 |
Proinflammatory and vasoactive effects of Aβ in the cerebrovasculature KP Townsend, D Obregon, A Quadros, N Patel, CH Volmar, D Paris, ... Annals of the New York Academy of Sciences 977 (1), 65-76, 2002 | 118 | 2002 |
Drug and disease signature integration identifies synergistic combinations in glioblastoma V Stathias, AM Jermakowicz, ME Maloof, M Forlin, W Walters, RK Suter, ... Nature communications 9 (1), 5315, 2018 | 110 | 2018 |
Plasticity of the electric organ discharge waveform of male Brachyhypopomus pinnicaudatus. II. Social effects CR Franchina, VL Salazar, CH Volmar, PK Stoddard Journal of Comparative Physiology A 187, 45-52, 2001 | 81 | 2001 |
The BET-bromodomain inhibitor JQ1 reduces inflammation and tau phosphorylation at Ser396 in the brain of the 3xTg model of Alzheimer’s disease M Magistri, D Velmeshev, M Makhmutova, P Patel, G C. Sartor, ... Current Alzheimer Research 13 (9), 985-995, 2016 | 78 | 2016 |
M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer’s disease genes and improving memory CH Volmar, H Salah-Uddin, KJ Janczura, P Halley, G Lambert, A Wodrich, ... Proceedings of the National Academy of Sciences 114 (43), E9135-E9144, 2017 | 67 | 2017 |
Sexual dimorphism in the 3xTg-AD mouse model and its impact on pre-clinical research JL Dennison, NR Ricciardi, I Lohse, CH Volmar, C Wahlestedt Journal of Alzheimer's disease 80 (1), 41-52, 2021 | 66 | 2021 |
Amplifying gene expression with RNA-targeted therapeutics O Khorkova, J Stahl, A Joji, CH Volmar, C Wahlestedt Nature Reviews Drug Discovery 22 (7), 539-561, 2023 | 64 | 2023 |
A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease JA Timmons, PJ Atherton, O Larsson, S Sood, IO Blokhin, RJ Brogan, ... Nucleic acids research 46 (15), 7772-7792, 2018 | 63 | 2018 |
Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins GC Sartor, AM Malvezzi, A Kumar, NS Andrade, HJ Wiedner, SJ Vilca, ... Journal of Neuroscience 39 (4), 612-626, 2019 | 62 | 2019 |
Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study RT Swords, D Azzam, H Al-Ali, I Lohse, CH Volmar, JM Watts, A Perez, ... Leukemia Research 64, 34-41, 2018 | 61 | 2018 |
Diagnostic utility of APOE, soluble CD40, CD40L, and Aβ1–40 levels in plasma in Alzheimer’s disease G Ait-ghezala, L Abdullah, CH Volmar, D Paris, CA Luis, A Quadros, ... Cytokine 44 (2), 283-287, 2008 | 56 | 2008 |
Vitamin C sensitizes melanoma to BET inhibitors S Mustafi, V Camarena, CH Volmar, TC Huff, DW Sant, SP Brothers, ... Cancer research 78 (2), 572-583, 2018 | 53 | 2018 |
Behavioral effects of CD40–CD40L pathway disruption in aged PSAPP mice JT Roach, CH Volmar, S Dwivedi, T Town, R Crescentini, F Crawford, ... Brain research 1015 (1-2), 161-168, 2004 | 45 | 2004 |
Differential Effects of the Gβ5-RGS7 Complex on Muscarinic M3 Receptor–Induced Ca2+ Influx and Release D Karpinsky-Semper, CH Volmar, SP Brothers, VZ Slepak Molecular pharmacology 85 (5), 758-768, 2014 | 42 | 2014 |