| Skeletal aging and osteoporosis: mechanisms and therapeutics A Chandra, J Rajawat International journal of molecular sciences 22 (7), 3553, 2021 | 192 | 2021 |
| Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression A Chandra, S Lan, J Zhu, VA Siclari, L Qin Journal of Biological Chemistry 288 (28), 20488-20498, 2013 | 158 | 2013 |
| Bone aging, cellular senescence, and osteoporosis RJ Pignolo, SF Law, A Chandra Journal of Bone and Mineral Research Plus 5 (4), e10488, 2021 | 139 | 2021 |
| EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation H Jia, X Ma, W Tong, B Doyran, Z Sun, L Wang, X Zhang, Y Zhou, F Badar, ... Proceedings of the National Academy of Sciences 113 (50), 14360-14365, 2016 | 128 | 2016 |
| Mesenchymal progenitors residing close to the bone surface are functionally distinct from those in the central bone marrow VA Siclari, J Zhu, K Akiyama, F Liu, X Zhang, A Chandra, HD Nah, S Shi, ... Bone 53 (2), 575-586, 2013 | 114 | 2013 |
| Targeted reduction of senescent cell burden alleviates focal radiotherapy‐related bone loss A Chandra, AB Lagnado, JN Farr, DG Monroe, S Park, C Hachfeld, ... Journal of Bone and Mineral Research 35 (6), 1119-1131, 2020 | 111 | 2020 |
| PTH1–34 alleviates radiotherapy-induced local bone loss by improving osteoblast and osteocyte survival A Chandra, T Lin, MB Tribble, J Zhu, AR Altman, WJ Tseng, Y Zhang, ... Bone 67, 33-40, 2014 | 110 | 2014 |
| Suppression of sclerostin alleviates radiation‐induced bone loss by protecting bone‐forming cells and their progenitors through distinct mechanisms A Chandra, T Lin, T Young, W Tong, X Ma, WJ Tseng, I Kramer, ... Journal of Bone and Mineral Research 32 (2), 360-372, 2017 | 109 | 2017 |
| Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model X Zhang, J Zhu, F Liu, Y Li, A Chandra, LS Levin, F Beier, ... Bone research 2 (1), 1-12, 2014 | 81 | 2014 |
| Targeted clearance of p21‐ but not p16‐positive senescent cells prevents radiation‐induced osteoporosis and increased marrow adiposity A Chandra, AB Lagnado, JN Farr, M Doolittle, T Tchkonia, JL Kirkland, ... Aging Cell 21 (5), e13602, 2022 | 77 | 2022 |
| PTH1–34 blocks radiation-induced osteoblast apoptosis by enhancing DNA repair through canonical Wnt pathway A Chandra, T Lin, J Zhu, W Tong, Y Huo, H Jia, Y Zhang, XS Liu, ... Journal of Biological Chemistry 290 (1), 157-167, 2015 | 76 | 2015 |
| Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and-independent pathways X Zhang, J Zhu, Y Li, T Lin, VA Siclari, A Chandra, EM Candela, ... Journal of Biological Chemistry 288 (45), 32229-32240, 2013 | 70 | 2013 |
| Loading‐induced reduction in sclerostin as a mechanism of subchondral bone plate sclerosis in mouse knee joints during late‐stage osteoarthritis H Jia, X Ma, Y Wei, W Tong, RJ Tower, A Chandra, L Wang, Z Sun, ... Arthritis & Rheumatology 70 (2), 230-241, 2018 | 67 | 2018 |
| PTH prevents the adverse effects of focal radiation on bone architecture in young rats A Chandra, S Lan, J Zhu, T Lin, X Zhang, VA Siclari, AR Altman, ... Bone 55 (2), 449-457, 2013 | 61 | 2013 |
| Quantification of skeletal growth, modeling, and remodeling by in vivo micro computed tomography AR Altman, WJ Tseng, CMJ de Bakker, A Chandra, S Lan, BK Huh, S Luo, ... Bone 81, 370-379, 2015 | 55 | 2015 |
| 3D image registration is critical to ensure accurate detection of longitudinal changes in trabecular bone density, microstructure, and stiffness measurements in rat tibiae by … S Lan, S Luo, BK Huh, A Chandra, AR Altman, L Qin, XS Liu Bone 56 (1), 83-90, 2013 | 54 | 2013 |
| Amphiregulin-EGFR signaling mediates the migration of bone marrow mesenchymal progenitors toward PTH-stimulated osteoblasts and osteocytes J Zhu, VA Siclari, F Liu, JM Spatz, A Chandra, P Divieti Pajevic, L Qin PloS one 7 (12), e50099, 2012 | 53 | 2012 |
| Targeting cell senescence for the treatment of age-related bone loss RJ Pignolo, RM Samsonraj, SF Law, H Wang, A Chandra Current osteoporosis reports 17, 70-85, 2019 | 47 | 2019 |
| Potential role of senescence in radiation-induced damage of the aged skeleton A Chandra, SS Park, RJ Pignolo Bone 120, 423-431, 2019 | 46 | 2019 |
| Periosteal mesenchymal progenitor dysfunction and extraskeletally‐derived fibrosis contribute to atrophic fracture nonunion L Wang, RJ Tower, A Chandra, L Yao, W Tong, Z Xiong, K Tang, Y Zhang, ... Journal of Bone and Mineral Research 34 (3), 520-532, 2019 | 42 | 2019 |
Ling QinAssociate Professor of Orthopaedics Surgery, University of Pennsylvania確認したメール アドレス: pennmedicine.upenn.edu
