Medicinal organometallic chemistry: designing metal arene complexes as anticancer agents AFA Peacock, PJ Sadler Chemistry–An Asian Journal 3 (11), 1890-1899, 2008 | 470 | 2008 |
Hydrolytic catalysis and structural stabilization in a designed metalloprotein ML Zastrow, AFA Peacock, JA Stuckey, VL Pecoraro Nature Chemistry 4 (2), 118-123, 2012 | 390 | 2012 |
Tuning the reactivity of osmium (II) and ruthenium (II) arene complexes under physiological conditions AFA Peacock, A Habtemariam, R Fernández, V Walland, FPA Fabbiani, ... Journal of the American Chemical Society 128 (5), 1739-1748, 2006 | 306 | 2006 |
In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model A Bergamo, A Masi, AFA Peacock, A Habtemariam, PJ Sadler, G Sava Journal of inorganic biochemistry 104 (1), 79-86, 2010 | 233 | 2010 |
Osmium (II) and ruthenium (II) arene maltolato complexes: rapid hydrolysis and nucleobase binding AFA Peacock, M Melchart, RJ Deeth, A Habtemariam, S Parsons, ... Chemistry–A European Journal 13 (9), 2601-2613, 2007 | 200 | 2007 |
Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N, O-chelating ligands to achieve cancer cell cytotoxicity AFA Peacock, S Parsons, PJ Sadler Journal of the American Chemical Society 129 (11), 3348-3357, 2007 | 183 | 2007 |
Chloro half-sandwich osmium (II) complexes: influence of chelated N, N-ligands on hydrolysis, guanine binding, and cytotoxicity AFA Peacock, A Habtemariam, SA Moggach, A Prescimone, S Parsons, ... Inorganic chemistry 46 (10), 4049-4059, 2007 | 141 | 2007 |
Organometallic osmium (II) arene anticancer complexes containing picolinate derivatives SH van Rijt, AFA Peacock, RDL Johnstone, S Parsons, PJ Sadler Inorganic chemistry 48 (4), 1753-1762, 2009 | 135 | 2009 |
DNA interactions of monofunctional organometallic osmium (II) antitumor complexes in cell-free media H Kostrhunova, J Florian, O Novakova, AFA Peacock, PJ Sadler, ... Journal of Medicinal Chemistry 51 (12), 3635-3643, 2008 | 113 | 2008 |
Topical delivery of anti-VEGF drugs to the ocular posterior segment using cell-penetrating peptides F De Cogan, LJ Hill, A Lynch, PJ Morgan-Warren, J Lechner, MR Berwick, ... Investigative ophthalmology & visual science 58 (5), 2578-2590, 2017 | 101 | 2017 |
De novo design of Ln (III) coiled coils for imaging applications MR Berwick, DJ Lewis, AW Jones, RA Parslow, TR Dafforn, HJ Cooper, ... Journal of the American Chemical Society 136 (4), 1166-1169, 2014 | 73 | 2014 |
Catalysis of regioselective reduction of NAD+ by ruthenium(II) arene complexes under biologically relevant conditions YK Yan, M Melchart, A Habtemariam, AFA Peacock, PJ Sadler JBIC Journal of Biological Inorganic Chemistry 11, 483-488, 2006 | 73 | 2006 |
Structural comparisons of apo-and metalated three-stranded coiled coils clarify metal binding determinants in thiolate containing designed peptides S Chakraborty, DS Touw, AFA Peacock, J Stuckey, VL Pecoraro Journal of the American Chemical Society 132 (38), 13240-13250, 2010 | 65 | 2010 |
Using diastereopeptides to control metal ion coordination in proteins AFA Peacock, L Hemmingsen, VL Pecoraro Proceedings of the National Academy of Sciences 105 (43), 16566-16571, 2008 | 65 | 2008 |
Incorporating metals into de novo proteins AFA Peacock Current Opinion in Chemical Biology 17 (6), 934-939, 2013 | 62 | 2013 |
Antimicrobial peptide coatings for hydroxyapatite: electrostatic and covalent attachment of antimicrobial peptides to surfaces L Townsend, RL Williams, O Anuforom, MR Berwick, F Halstead, ... Journal of The Royal Society Interface 14 (126), 20160657, 2017 | 57 | 2017 |
Preparation and antimicrobial evaluation of polyion complex (PIC) nanoparticles loaded with polymyxin B I Insua, S Majok, AFA Peacock, AM Krachler, F Fernandez-Trillo European polymer journal 87, 478-486, 2017 | 53 | 2017 |
Switching the chirality of the metal environment alters the coordination mode in designed peptides AFA Peacock, JA Stuckey, VL Pecoraro Wiley-VCH Verlag, 2009 | 48 | 2009 |
Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides AFA Peacock, O Iranzo, VL Pecoraro Dalton Transactions, 2271-2280, 2009 | 42 | 2009 |
Enzyme-responsive polyion complex (PIC) nanoparticles for the targeted delivery of antimicrobial polymers I Insua, E Liamas, Z Zhang, AFA Peacock, AM Krachler, ... Polymer Chemistry 7 (15), 2684-2690, 2016 | 40 | 2016 |