フォロー
Dr. Lukas Schulig
Dr. Lukas Schulig
Researcher at University of Greifswald, Institute of Pharmacy, MedChem
確認したメール アドレス: uni-greifswald.de
タイトル
引用先
引用先
Interconnection of sulfides and sulfoxides in medicinal chemistry
AS Surur, L Schulig, A Link
Archiv der Pharmazie 352 (1), 1800248, 2019
922019
Extensively drug-resistant Klebsiella pneumoniae counteracts fitness and virulence costs that accompanied ceftazidime-avibactam resistance acquisition
E Eger, M Schwabe, L Schulig, NO Hübner, JA Bohnert, UT Bornscheuer, ...
Microbiology spectrum 10 (3), e00148-22, 2022
272022
Flupirtine and retigabine as templates for ligand-based drug design of KV 7.2/3 activators
AS Surur, C Bock, K Beirow, K Wurm, L Schulig, MK Kindermann, ...
Organic & Biomolecular Chemistry 17 (18), 4512-4522, 2019
272019
Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV7.2/KV7.3 Channel Opening Activity
C Bock, AS Surur, K Beirow, MK Kindermann, L Schulig, A Bodtke, ...
ChemMedChem 14 (9), 952-964, 2019
222019
Subcritical fluid chromatography at sub-ambient temperatures for the chiral resolution of ketamine metabolites with rapid-onset antidepressant effects
RK Hofstetter, F Potlitz, L Schulig, S Kim, M Hasan, A Link
Molecules 24 (10), 1927, 2019
202019
Advances in the discovery of new chemotypes through ultra-large library docking
F Potlitz, A Link, L Schulig
Expert opinion on drug discovery 18 (3), 303-313, 2023
192023
Replica-based protein structure sampling methods II: advanced hybrid solvent TIGER2hs
N Geist, M Kulke, L Schulig, A Link, W Langel
The Journal of Physical Chemistry B 123 (28), 5995-6006, 2019
172019
Tetrahydroindoles as multipurpose screening compounds and novel sirtuin inhibitors
S Vojacek, L Schulig, N Wössner, N Geist, W Langel, M Jung, D Schade, ...
ChemMedChem 14 (8), 853-864, 2019
172019
Modifications of the triaminoaryl metabophore of flupirtine and retigabine aimed at avoiding quinone diimine formation
KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link
ACS omega 7 (9), 7989-8012, 2022
152022
The EyeFlowCell: development of a 3D-printed dissolution test setup for intravitreal dosage forms
T Auel, L Großmann, L Schulig, W Weitschies, A Seidlitz
Pharmaceutics 13 (9), 1394, 2021
132021
Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on KV7.2/KV7.3 Channel Opening Activity
AS Surur, K Beirow, C Bock, L Schulig, MK Kindermann, A Bodtke, ...
ChemistryOpen 8 (1), 41-44, 2019
132019
Pneumococcal extracellular serine proteases: molecular analysis and impact on colonization and disease
MQ Ali, TP Kohler, L Schulig, G Burchhardt, S Hammerschmidt
Frontiers in Cellular and Infection Microbiology 11, 763152, 2021
122021
Synthesis and potassium KV 7 channel opening activity of thioether analogues of the analgesic flupirtine
C Bock, K Beirow, AS Surur, L Schulig, A Bodtke, PJ Bednarski, A Link
Organic & Biomolecular Chemistry 16 (45), 8695-8699, 2018
112018
Carba analogues of flupirtine and retigabine with improved oxidation resistance and reduced risk of quinoid metabolite formation
KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link
ChemMedChem 17 (16), e202200262, 2022
102022
Activation of sirtuin 2 inhibitors employing photoswitchable geometry and aqueous solubility
CW Grathwol, N Wössner, S Behnisch‐Cornwell, L Schulig, L Zhang, ...
ChemMedChem 15 (15), 1480-1489, 2020
102020
A hypothesized mechanism for chronic pancreatitis caused by the N34S mutation of serine protease inhibitor Kazal-type 1 based on conformational studies
M Kulke, F Nagel, L Schulig, N Geist, M Gabor, J Mayerle, M M Lerch, ...
Journal of Inflammation Research, 2111-2119, 2021
72021
Replacing the oxidation‐sensitive triaminoaryl chemotype of problematic KV7 channel openers: Exploration of a nicotinamide scaffold
KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link
Archiv der Pharmazie 356 (2), 2200473, 2023
62023
Nuclear import of BCL11B is mediated by a classical nuclear localization signal and not the Krüppel-like zinc fingers
P Grabarczyk, M Delin, D Rogińska, L Schulig, H Forkel, M Depke, A Link, ...
Journal of Cell Science 134 (23), jcs258655, 2021
52021
Supercritical fluid extraction–supercritical fluid chromatography of saliva: Single‐quadrupole mass spectrometry monitoring of caffeine for gastric emptying studies
RK Hofstetter, L Schulig, J Bethmann, M Grimm, M Sager, P Aude, ...
Journal of Separation Science 44 (19), 3700-3716, 2021
52021
Fundamental redesign of the TIGER2hs kernel to address severe parameter sensitivity
L Schulig, N Geist, M Delcea, A Link, M Kulke
Journal of Chemical Information and Modeling 62 (17), 4200-4209, 2022
42022
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