Interconnection of sulfides and sulfoxides in medicinal chemistry AS Surur, L Schulig, A Link Archiv der Pharmazie 352 (1), 1800248, 2019 | 92 | 2019 |
Extensively drug-resistant Klebsiella pneumoniae counteracts fitness and virulence costs that accompanied ceftazidime-avibactam resistance acquisition E Eger, M Schwabe, L Schulig, NO Hübner, JA Bohnert, UT Bornscheuer, ... Microbiology spectrum 10 (3), e00148-22, 2022 | 27 | 2022 |
Flupirtine and retigabine as templates for ligand-based drug design of KV 7.2/3 activators AS Surur, C Bock, K Beirow, K Wurm, L Schulig, MK Kindermann, ... Organic & Biomolecular Chemistry 17 (18), 4512-4522, 2019 | 27 | 2019 |
Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV7.2/KV7.3 Channel Opening Activity C Bock, AS Surur, K Beirow, MK Kindermann, L Schulig, A Bodtke, ... ChemMedChem 14 (9), 952-964, 2019 | 22 | 2019 |
Subcritical fluid chromatography at sub-ambient temperatures for the chiral resolution of ketamine metabolites with rapid-onset antidepressant effects RK Hofstetter, F Potlitz, L Schulig, S Kim, M Hasan, A Link Molecules 24 (10), 1927, 2019 | 20 | 2019 |
Advances in the discovery of new chemotypes through ultra-large library docking F Potlitz, A Link, L Schulig Expert opinion on drug discovery 18 (3), 303-313, 2023 | 19 | 2023 |
Replica-based protein structure sampling methods II: advanced hybrid solvent TIGER2hs N Geist, M Kulke, L Schulig, A Link, W Langel The Journal of Physical Chemistry B 123 (28), 5995-6006, 2019 | 17 | 2019 |
Tetrahydroindoles as multipurpose screening compounds and novel sirtuin inhibitors S Vojacek, L Schulig, N Wössner, N Geist, W Langel, M Jung, D Schade, ... ChemMedChem 14 (8), 853-864, 2019 | 17 | 2019 |
Modifications of the triaminoaryl metabophore of flupirtine and retigabine aimed at avoiding quinone diimine formation KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link ACS omega 7 (9), 7989-8012, 2022 | 15 | 2022 |
The EyeFlowCell: development of a 3D-printed dissolution test setup for intravitreal dosage forms T Auel, L Großmann, L Schulig, W Weitschies, A Seidlitz Pharmaceutics 13 (9), 1394, 2021 | 13 | 2021 |
Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on KV7.2/KV7.3 Channel Opening Activity AS Surur, K Beirow, C Bock, L Schulig, MK Kindermann, A Bodtke, ... ChemistryOpen 8 (1), 41-44, 2019 | 13 | 2019 |
Pneumococcal extracellular serine proteases: molecular analysis and impact on colonization and disease MQ Ali, TP Kohler, L Schulig, G Burchhardt, S Hammerschmidt Frontiers in Cellular and Infection Microbiology 11, 763152, 2021 | 12 | 2021 |
Synthesis and potassium KV 7 channel opening activity of thioether analogues of the analgesic flupirtine C Bock, K Beirow, AS Surur, L Schulig, A Bodtke, PJ Bednarski, A Link Organic & Biomolecular Chemistry 16 (45), 8695-8699, 2018 | 11 | 2018 |
Carba analogues of flupirtine and retigabine with improved oxidation resistance and reduced risk of quinoid metabolite formation KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link ChemMedChem 17 (16), e202200262, 2022 | 10 | 2022 |
Activation of sirtuin 2 inhibitors employing photoswitchable geometry and aqueous solubility CW Grathwol, N Wössner, S Behnisch‐Cornwell, L Schulig, L Zhang, ... ChemMedChem 15 (15), 1480-1489, 2020 | 10 | 2020 |
A hypothesized mechanism for chronic pancreatitis caused by the N34S mutation of serine protease inhibitor Kazal-type 1 based on conformational studies M Kulke, F Nagel, L Schulig, N Geist, M Gabor, J Mayerle, M M Lerch, ... Journal of Inflammation Research, 2111-2119, 2021 | 7 | 2021 |
Replacing the oxidation‐sensitive triaminoaryl chemotype of problematic KV7 channel openers: Exploration of a nicotinamide scaffold KW Wurm, FM Bartz, L Schulig, A Bodtke, PJ Bednarski, A Link Archiv der Pharmazie 356 (2), 2200473, 2023 | 6 | 2023 |
Nuclear import of BCL11B is mediated by a classical nuclear localization signal and not the Krüppel-like zinc fingers P Grabarczyk, M Delin, D Rogińska, L Schulig, H Forkel, M Depke, A Link, ... Journal of Cell Science 134 (23), jcs258655, 2021 | 5 | 2021 |
Supercritical fluid extraction–supercritical fluid chromatography of saliva: Single‐quadrupole mass spectrometry monitoring of caffeine for gastric emptying studies† RK Hofstetter, L Schulig, J Bethmann, M Grimm, M Sager, P Aude, ... Journal of Separation Science 44 (19), 3700-3716, 2021 | 5 | 2021 |
Fundamental redesign of the TIGER2hs kernel to address severe parameter sensitivity L Schulig, N Geist, M Delcea, A Link, M Kulke Journal of Chemical Information and Modeling 62 (17), 4200-4209, 2022 | 4 | 2022 |