Gut Microbiota-Dependent Trimethylamine N-Oxide (TMAO) Pathway Contributes to Both Development of Renal Insufficiency and Mortality Risk in Chronic Kidney … WHW Tang, Z Wang, DJ Kennedy, Y Wu, JA Buffa, B Agatisa-Boyle, XS Li, ... Circulation research 116 (3), 448-455, 2015 | 1186 | 2015 |
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors XS Li, S Obeid, R Klingenberg, B Gencer, F Mach, L Räber, S Windecker, ... European heart journal 38 (11), 814-824, 2017 | 497 | 2017 |
Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women Z Wang, N Bergeron, BS Levison, XS Li, S Chiu, X Jia, RA Koeth, L Li, ... European heart journal 40 (7), 583–594, 2019 | 442 | 2019 |
The lipid whisker model of the structure of oxidized cell membranes ME Greenberg, XM Li, BG Gugiu, X Gu, J Qin, RG Salomon, SL Hazen Journal of biological chemistry 283 (4), 2385-2396, 2008 | 381 | 2008 |
Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks XM Li, WHW Tang, MK Mosior, Y Huang, Y Wu, W Matter, V Gao, ... Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1696-1705, 2013 | 343 | 2013 |
Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry Z Wang, BS Levison, JE Hazen, L Donahue, XM Li, SL Hazen Analytical biochemistry 455, 35-40, 2014 | 342 | 2014 |
Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex Y Huang, Z Wu, M Riwanto, S Gao, BS Levison, X Gu, X Fu, MA Wagner, ... The Journal of clinical investigation 123 (9), 3815-3828, 2013 | 332 | 2013 |
l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans RA Koeth, BR Lam-Galvez, J Kirsop, Z Wang, BS Levison, X Gu, ... The Journal of clinical investigation 129 (1), 373-387, 2019 | 316 | 2019 |
Gut Microbiota–Dependent Trimethylamine N-Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes A Haghikia, XS Li, TG Liman, N Bledau, D Schmidt, F Zimmermann, ... Arteriosclerosis, thrombosis, and vascular biology 38 (9), 2225-2235, 2018 | 298 | 2018 |
The TMAO-producing enzyme flavin-containing monooxygenase 3 regulates obesity and the beiging of white adipose tissue RC Schugar, DM Shih, M Warrier, RN Helsley, A Burrows, D Ferguson, ... Cell reports 19 (12), 2451-2461, 2017 | 293 | 2017 |
Intestinal Microbiota‐Generated Metabolite Trimethylamine‐N‐Oxide and 5‐Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of … V Senthong, Z Wang, XS Li, Y Fan, Y Wu, WH Wilson Tang, SL Hazen Journal of the American Heart Association 5 (6), e002816, 2016 | 290 | 2016 |
Plasma Trimethylamine N-Oxide, a Gut Microbe–Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden V Senthong, XS Li, T Hudec, J Coughlin, Y Wu, B Levison, Z Wang, ... Journal of the American College of Cardiology 67 (22), 2620-2628, 2016 | 258 | 2016 |
Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus WHW Tang, Z Wang, XS Li, Y Fan, DS Li, Y Wu, SL Hazen Clinical chemistry 63 (1), 297-306, 2017 | 234 | 2017 |
Cholesterol decreases the interfacial elasticity and detergent solubility of sphingomyelins XM Li, MM Momsen, JM Smaby, HL Brockman, RE Brown Biochemistry 40 (20), 5954-5963, 2001 | 178 | 2001 |
The artificial sweetener erythritol and cardiovascular event risk M Witkowski, I Nemet, H Alamri, J Wilcox, N Gupta, N Nimer, A Haghikia, ... Nature medicine 29 (3), 710-718, 2023 | 158 | 2023 |
Sphingomyelin interfacial behavior: the impact of changing acyl chain composition XM Li, JM Smaby, MM Momsen, HL Brockman, RE Brown Biophysical journal 78 (4), 1921-1931, 2000 | 158 | 2000 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk XS Li, Z Wang, T Cajka, JA Buffa, I Nemet, AG Hurd, X Gu, SM Skye, ... JCI insight 3 (6), :e99096. https://doi.org/10.1172/jci.ins, 2018 | 154 | 2018 |
Genetic architecture of atherosclerosis in mice: a systems genetics analysis of common inbred strains BJ Bennett, RC Davis, M Civelek, L Orozco, J Wu, H Qi, C Pan, ... PLoS genetics 11 (12), e1005711, 2015 | 146 | 2015 |
Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk N Bergeron, PT Williams, R Lamendella, N Faghihnia, A Grube, X Li, ... British Journal of Nutrition 116 (12), 2020-2029, 2016 | 143 | 2016 |
Gut microbes impact stroke severity via the trimethylamine N-oxide pathway W Zhu, KA Romano, L Li, JA Buffa, N Sangwan, P Prakash, AN Tittle, ... Cell host & microbe 29 (7), 1199-1208. e5, 2021 | 118 | 2021 |