| ApoE in Alzheimer’s disease: pathophysiology and therapeutic strategies AC Raulin, SV Doss, ZA Trottier, TC Ikezu, G Bu, CC Liu Molecular neurodegeneration 17 (1), 72, 2022 | 350 | 2022 |
| APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia CC Liu, ME Murray, X Li, N Zhao, N Wang, MG Heckman, F Shue, ... Science translational medicine 13 (613), eabc9375, 2021 | 72 | 2021 |
| Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer’s disease CC Liu, N Wang, Y Chen, Y Inoue, F Shue, Y Ren, M Wang, W Qiao, ... Nature immunology 24 (11), 1854-1866, 2023 | 57 | 2023 |
| Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia N Zhao, W Qiao, F Li, Y Ren, J Zheng, YA Martens, X Wang, L Li, CC Liu, ... Journal of Experimental Medicine 219 (12), e20212479, 2022 | 53 | 2022 |
| Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination N Wang, M Wang, S Jeevaratnam, C Rosenberg, TC Ikezu, F Shue, ... Molecular neurodegeneration 17 (1), 75, 2022 | 40 | 2022 |
| APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology Y Jin, F Li, B Sonoustoun, NC Kondru, YA Martens, W Qiao, MG Heckman, ... Acta neuropathologica 143 (6), 641-662, 2022 | 40 | 2022 |
| Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology W Qiao, Y Chen, J Zhong, BJ Madden, CM Charlesworth, YA Martens, ... Molecular neurodegeneration 18 (1), 8, 2023 | 14 | 2023 |
| APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids J Zhao, TC Ikezu, W Lu, JR Macyczko, Y Li, LJ Lewis-Tuffin, YA Martens, ... Stem Cell Research & Therapy 14 (1), 214, 2023 | 12 | 2023 |
| Suppression of Wnt/β-Catenin Signaling Is Associated with Downregulation of Wnt1, PORCN, and Rspo2 in Alzheimer’s Disease JR Macyczko, N Wang, J Zhao, Y Ren, W Lu, TC Ikezu, N Zhao, CC Liu, ... Molecular neurobiology 60 (1), 26-35, 2023 | 9 | 2023 |
| Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs Y Jin, F Li, Z Li, TC Ikezu, J O’Leary, M Selvaraj, Y Zhu, YA Martens, ... Science Advances 10 (37), eadk3700, 2024 | 4 | 2024 |
| APOE2 Exacerbates TDP‐43 Related Toxicity in the Absence of Alzheimer Pathology AD Meneses, S Koga, Z Li, J O'Leary, F Li, K Chen, A Murakami, W Qiao, ... Annals of neurology 93 (4), 830-843, 2023 | 4 | 2023 |
| Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease AC Raulin, SV Doss, MG Heckman, EC Craver, Z Li, TC Ikezu, H Sekiya, ... Acta Neuropathologica Communications 12 (1), 25, 2024 | 2 | 2024 |
| APOE genotype modifies benefits of calorie restriction against aging W Qiao, Y Chen, Y Ren, TC Ikezu, S Johnson, F Li, K Chen, M Pan, ... Alzheimer's & Dementia 20 (Suppl 1), e085702, 2025 | | 2025 |
| Basic Science and Pathogenesis W Qiao, Y Chen, Y Ren, TC Ikezu, S Johnson, F Li, K Chen, M Pan, ... Alzheimer's & dementia: the journal of the Alzheimer's Association 20, e085702, 2024 | | 2024 |
