Diet‐induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease L Ho, W Qin, PN Pompl, Z Xiang, J Wang, Z Zhao, Y Peng, G Cambareri, ... The FASEB journal 18 (7), 902-904, 2004 | 783 | 2004 |
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction W Qin, T Yang, L Ho, Z Zhao, J Wang, L Chen, W Zhao, M Thiyagarajan, ... Journal of Biological Chemistry 281 (31), 21745-21754, 2006 | 768 | 2006 |
Grape-derived polyphenolics prevent Aβ oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease J Wang, L Ho, W Zhao, K Ono, C Rosensweig, L Chen, N Humala, ... Journal of Neuroscience 28 (25), 6388-6392, 2008 | 485 | 2008 |
Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene … B Gong, Y Pan, P Vempati, W Zhao, L Knable, L Ho, J Wang, M Sastre, ... Neurobiology of aging 34 (6), 1581-1588, 2013 | 433 | 2013 |
Moderate consumption of Cabernet Sauvignon attenuates A neuropathology in a mouse model of Alzheimer's disease J Wang, L Ho, Z Zhao, I Seror, N Humala, DL Dickstein, M Thiyagarajan, ... The FASEB Journal 20 (13), 2313-2320, 2006 | 389 | 2006 |
Valsartan lowers brain β-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease J Wang, L Ho, L Chen, Z Zhao, W Zhao, X Qian, N Humala, I Seror, ... The Journal of clinical investigation 117 (11), 3393-3402, 2007 | 383 | 2007 |
Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. Wang J, Ho L, Qin W, Rocher AB, Seror I, Humala N, Maniar K, Dolios G, Wang ... FASEB J. 19 (6), 659-61., 2005 | 371* | 2005 |
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis Z Zhao, DJ Lange, A Voustianiouk, D MacGrogan, L Ho, J Suh, N Humala, ... BMC neuroscience 7, 1-10, 2006 | 356 | 2006 |
Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment GM Pasinetti, J Wang, L Ho, W Zhao, L Dubner Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (6 …, 2015 | 295 | 2015 |
Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease L Ho, MG Ferruzzi, EM Janle, J Wang, B Gong, TY Chen, J Lobo, ... The FASEB Journal 27 (2), 769, 2013 | 266 | 2013 |
Effects of Grape Seed-derived Polyphenols on Amyloid β-Protein Self-assembly and Cytotoxicity*♦ K Ono, MM Condron, L Ho, J Wang, W Zhao, GM Pasinetti, DB Teplow Journal of Biological Chemistry 283 (47), 32176-32187, 2008 | 264 | 2008 |
Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment J Wang, MG Ferruzzi, L Ho, J Blount, EM Janle, B Gong, Y Pan, ... Journal of Neuroscience 32 (15), 5144-5150, 2012 | 261 | 2012 |
Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice J Wang, GE Hodes, H Zhang, S Zhang, W Zhao, SA Golden, W Bi, ... Nature communications 9 (1), 477, 2018 | 251 | 2018 |
Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes I Santa-Maria, M Varghese, H Ksiȩżak-Reding, A Dzhun, J Wang, ... Journal of Biological Chemistry 287 (24), 20522-20533, 2012 | 166 | 2012 |
Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease W Zhao, M Varghese, P Vempati, A Dzhun, A Cheng, J Wang, D Lange, ... PloS one 7 (11), e49191, 2012 | 155 | 2012 |
Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease J Wang, I Santa-Maria, L Ho, H Ksiezak-Reding, K Ono, DB Teplow, ... Journal of Alzheimer's Disease 22 (2), 653-661, 2010 | 143 | 2010 |
Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration L Ho, LH Chen, J Wang, W Zhao, ST Talcott, K Ono, D Teplow, N Humala, ... Journal of Alzheimer's Disease 16 (1), 59-72, 2009 | 143 | 2009 |
Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications J Wang, W Bi, A Cheng, D Freire, P Vempati, W Zhao, B Gong, EM Janle, ... Frontiers in aging neuroscience 6, 42, 2014 | 140 | 2014 |
Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction‐induced prevention of Alzheimer's disease‐type amyloid neuropathology and spatial memory … W Qin, W Zhao, L Ho, J Wang, K Walsh, S Gandy, GM Pasinetti Annals of the New York Academy of Sciences 1147 (1), 335-347, 2008 | 137 | 2008 |
The role of Sirt1: at the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology J Wang, H Fivecoat, L Ho, Y Pan, E Ling, GM Pasinetti Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (8), 1690-1694, 2010 | 123 | 2010 |