Preferential formation of benzo [a] pyrene adducts at lung cancer mutational hotspots in P53 MF Denissenko, A Pao, M Tang, GP Pfeifer Science 274 (5286), 430-432, 1996 | 2352 | 1996 |
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21. 3 R Dammann, C Li, JH Yoon, PL Chin, S Bates, GP Pfeifer Nature genetics 25 (3), 315-319, 2000 | 1635 | 2000 |
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers GP Pfeifer, MF Denissenko, M Olivier, N Tretyakova, SS Hecht, P Hainaut Oncogene 21 (48), 7435-7451, 2002 | 1425 | 2002 |
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes TP Gu, F Guo, H Yang, HP Wu, GF Xu, W Liu, ZG Xie, L Shi, X He, S Jin, ... Nature 477 (7366), 606-610, 2011 | 1353 | 2011 |
Mutations induced by ultraviolet light GP Pfeifer, YH You, A Besaratinia Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 571 (1 …, 2005 | 1056 | 2005 |
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine K Iqbal, SG Jin, GP Pfeifer, PE Szabó Proceedings of the National Academy of Sciences 108 (9), 3642-3647, 2011 | 817 | 2011 |
UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer GP Pfeifer, A Besaratinia Photochemical & photobiological sciences 11 (1), 90-97, 2012 | 581 | 2012 |
Aging and DNA methylation M Jung, GP Pfeifer BMC biology 13, 1-8, 2015 | 563 | 2015 |
Patterns of p53 G→ T transversions in lung cancers reflect the primary mutagenic signature of DNA-damage by tobacco smoke P Hainaut, GP Pfeifer Carcinogenesis 22 (3), 367-374, 2001 | 534 | 2001 |
Genomic sequencing and methylation analysis by ligation mediated PCR GP Pfeifer, SD Steigerwald, PR Mueller, B Wold, AD Riggs Science 246 (4931), 810-813, 1989 | 534 | 1989 |
Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine SG Jin, S Kadam, GP Pfeifer Nucleic acids research 38 (11), e125-e125, 2010 | 532 | 2010 |
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis MA Hahn, R Qiu, X Wu, AX Li, H Zhang, J Wang, J Jui, SG Jin, Y Jiang, ... Cell reports 3 (2), 291-300, 2013 | 515 | 2013 |
5-Hydroxymethylcytosine Is Strongly Depleted in Human Cancers but Its Levels Do Not Correlate with IDH1 Mutations SG Jin, Y Jiang, R Qiu, TA Rauch, Y Wang, G Schackert, D Krex, Q Lu, ... Cancer research 71 (24), 7360-7365, 2011 | 500 | 2011 |
X-chromosome inactivation and cell memory AD Riggs, GP Pfeifer Trends in Genetics 8 (5), 169-174, 1992 | 457 | 1992 |
Genomic mapping of 5-hydroxymethylcytosine in the human brain SG Jin, X Wu, AX Li, GP Pfeifer Nucleic acids research 39 (12), 5015-5024, 2011 | 452 | 2011 |
Cytosine methylation determines hot spots of DNA damage in the human P53 gene MF Denissenko, JX Chen, M Tang, GP Pfeifer Proceedings of the National Academy of Sciences 94 (8), 3893-3898, 1997 | 436 | 1997 |
Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21. 3 locus, occurs in a large percentage of human … R Dammann, G Yang, GP Pfeifer Cancer research 61 (7), 3105-3109, 2001 | 432 | 2001 |
Formation and processing of UV photoproducts: effects of DNA sequence and chromatin environment GP Pfeifer Photochemistry and photobiology 65 (2), 270-283, 1997 | 412 | 1997 |
Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein … AT Nguyen, TA Rauch, GP Pfeifer, VW Hu The FASEB Journal 24 (8), 3036, 2010 | 409 | 2010 |
A human B cell methylome at 100− base pair resolution TA Rauch, X Wu, X Zhong, AD Riggs, GP Pfeifer Proceedings of the National Academy of Sciences 106 (3), 671-678, 2009 | 406 | 2009 |